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Claudio Bruschini

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Publications associées (185)

Ghost imaging using two SPAD array detectors: a parameter study towards the realization of a 3D quantum microscope

Claudio Bruschini, Edoardo Charbon, Paul Mos, Yang Lin

Quantum ghost imaging can be an important tool in making optical measurements. One of the most useful aspects of ghost imaging is the unique ability to correlate two sets of independently collected information. We aim to use the principles of ghost imaging ...

Spie-Int Soc Optical Engineering2024

Efficient signal extraction for diffuse correlation spectroscopy with SPAD arrays at low photon regimes

Claudio Bruschini, Edoardo Charbon, Michael Alan Wayne

SPAD arrays have shown potential for improving SNR for diffuse correlation spectroscopy in low photon regimes. Here, we will explore different methods of integrating parallelized DCS signals in such regimes for deep blood flow extraction. ...

Optical Society of America2024

3D fluorescence molecular tomography utilizing a novel SPAD camera

Claudio Bruschini, Edoardo Charbon, Vikash Kumar Pandey, Arin Can Ülkü

3D Fluorescence Molecular Tomography (FMT) is an important pre-clinical tool for quantifying and characterizing molecular markers for different diseases. Herein, we demonstrate, for the first time, 3D K-Space FMT reconstructions using a large time-gated SP ...

SPIE2024

Quantum ghost imaging microscopy depth-of-field study

Claudio Bruschini, Edoardo Charbon, Paul Mos, Yang Lin, Michael Alan Wayne

Quantum ghost imaging approaches have been proposed to enhance biological microscopy, for example, using 2D visible detectors to provide IR images or providing additional dimensions of spatial or spectral information. Toward the goal of making such imaging ...

2024

Double multiplication region configuration for near-infrared sensitivity enhancement in silicon cmos single-photon avalanche diodes

Claudio Bruschini, Edoardo Charbon, Ekin Kizilkan, Utku Karaca

A near-infrared sensitivity enhanced substrate non-isolated silicon single-photon avalanche diode is disclosed, comprising a p-well layer (101), a high-voltage n-well (102), the p-well layer and the high- voltage n-well layer positioned against each other ...

2024

Coupling a recurrent neural network to SPAD TCSPC systems for real-time fluorescence lifetime imaging

Claudio Bruschini, Edoardo Charbon, Andrei Ardelean, Paul Mos, Yang Lin

Fluorescence lifetime imaging (FLI) has been receiving increased attention in recent years as a powerful diagnostic technique in biological and medical research. However, existing FLI systems often suffer from a tradeoff between processing speed, accuracy, ...

Nature Portfolio2024

Challenges and prospects for multi-chip microlens imprints on front-side illuminated SPAD imagers

Claudio Bruschini, Edoardo Charbon, Scott Anthony Lindner, Ivan Michel Antolovic, Vladimir Pesic, Tommaso Milanese

The overall sensitivity of frontside-illuminated, silicon single-photon avalanche diode (SPAD) arrays has often suffered from fill factor limitations. The fill factor loss can however be recovered by employing microlenses, whereby the challenges specific t ...

Optica Publishing Group2023

Superconducting quantum detectors and single photon charge control for mass spectrometry

Claudio Bruschini, Edoardo Charbon

Since the early 20th century, molecular beam research has led to many advances in physics and chemistry, from precision molecule metrology, over tests of fundamental symmetries, and molecular quantum optics to applied mass spectrometry. All such experiment ...

SPIE2023

Heralded Spectroscopy: a new single-particle probe for nanocrystal photophysics

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Ivan Michel Antolovic, Arin Can Ülkü

Semiconductor nanocrystals feature multiply-excited states that display intriguing physics and significantly impact nanocrystal-based technologies. Fluorescence supplies a natural probe to investigate these states. Still, direct observation of multiexciton ...

SPIE2023

Correlated-photon imaging at 10 volumetric images per second

Claudio Bruschini, Edoardo Charbon, Arin Can Ülkü, Paul Mos

The correlation properties of light provide an outstanding tool to overcome the limitations of traditional imaging techniques. A relevant case is represented by correlation plenoptic imaging (CPI), a quantum-inspired volumetric imaging protocol employing s ...

Nature Portfolio2023

NIR fluorescence lifetime macroscopic imaging with a novel time-gated SPAD camera

Claudio Bruschini, Edoardo Charbon

SwissSPAD3 is the latest of a family of widefield time-gated SPAD imagers developed for fluorescence lifetime imaging (FLI) applications. Its distinctive features are (i) the ability to define shorter gates than its predecessors (width W < 1 ns), (ii) supp ...

SPIE2023

Parallelized compressive spontaneous Raman imaging via SPAD arrays (Conference Presentation)

Claudio Bruschini, Edoardo Charbon, Samuel Burri

Compressive Raman imaging has emerged as a promising technique to speed up chemical imaging by compressing the data during acquisition. Yet, current scanning imaging speed is fundamentally limited by the sensors pixel dwell times of at best 1 µs. Here, we ...

SPIE2023

Method and device for performing spectrally and temporally resolved spectroscopy of single photon emission in a quantum device

Claudio Bruschini, Edoardo Charbon, Arin Can Ülkü

A light spectrometer including a laser configured to provide for a laser pulse (12), a quantum dot (30), an objective (21) configured to focus the laser pulse (12) onto the quantum dot (30) such that a fluorescent light beam is emitted from the quantum dot ...

2023

LinoSPAD2: a 512x1 linear SPAD camera with system-level 135-ps SPTR and a reconfigurable computational engine for time-resolved single-photon imaging

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Arin Can Ülkü, Tommaso Milanese

The LinoSPAD2 camera combines a 512×1 linear single-photon avalanche diode (SPAD) array with an FPGA-based photon-counting and time-stamping platform, to create a reconfigurable sensing system capable of detecting single photons. The read-out is fully para ...

SPIE2023

Neutron radiation hardness of single-photon avalanche diodes for future RICH detectors

Claudio Bruschini, Edoardo Charbon

The next generation of experiments in high energy particle physics will require a large increase in interaction density, which presents a challenge for particle detectors. Ring imaging Cherenkov detectors (RICH), planned for future upgrades of the LHCb, Be ...

IEEE2023

Single-photon avalanche diode fabricated in standard 55 nm bipolar-CMOS-DMOS technology with sub-20 V breakdown voltage

Claudio Bruschini, Edoardo Charbon, Myung Jae Lee, Won Yong Ha

This paper presents a single-photon avalanche diode (SPAD) in 55 nm bipolar-CMOSDMOS (BCD) technology. In order to realize a SPAD having sub-20 V breakdown voltage for mobile applications while preventing high tunneling noise, a high-voltage N-well availab ...

Optica Publishing Group2023

Extended Temperature Modeling of InGaAs/InP SPADs

Claudio Bruschini, Edoardo Charbon, Myung Jae Lee, Ekin Kizilkan, Utku Karaca, Vladimir Pesic

We present a simulation method to estimate the dark count rate (DCR), photon detection probability (PDP), and dark current of InGaAs/InP single-photon avalanche diodes (SPADs) from 225K to 300K. All simulations are performed completely in TCAD and match we ...

IEEE2023

Towards precise optical measurements of steady state of and small changes in resting membrane potentials

Claudio Bruschini, Edoardo Charbon, Michael Alan Wayne

CELL PRESS2023

Highly sensitive single-molecule detection of macromolecule ion beams

Claudio Bruschini, Edoardo Charbon

The analysis of proteins in the gas phase benefits from detectors that exhibit high efficiency and precise spatial resolution. Although modern secondary electron multipliers already address numerous analytical requirements, additional methods are desired f ...

AMER ASSOC ADVANCEMENT SCIENCE2023

Seeing Photons in Color

Claudio Bruschini, Edoardo Charbon, Paul Mos, Mohit Gupta

Megapixel single-photon avalanche diode (SPAD) arrays have been developed recently, opening up the possibility of deploying SPADs as general-purpose passive cameras for photography and computer vision. However, most previous work on SPADs has been limited ...

ASSOC COMPUTING MACHINERY2023

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