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Philippe Renaud

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Related publications (301)

Dielectrophoretic formation of cell aggregates mimicking tumors for in vitro study of electrochemotherapy

Philippe Renaud, Jonathan Bastien Cottet

2016

Bi-directional AC electrothermal micropump for on-chip biological applications

Philippe Renaud, Harald Van Lintel, Jürgen Brugger, Reza Hadjiaghaie Vafaie

The ability to control and pump high ionic strength fluids inside microchannels forms a major advantage for clinical diagnostics and drug screening processes, where high conductive biological and physiological buffers are used. Despite the known potential ...

Wiley-Blackwell2016

On-Chip Flow Cytometry

Philippe Renaud, Ana Valero

Springer Netherlands2016

An automated microreactor for semi-continuous biosensor measurements

Philippe Renaud, Harald Van Lintel, Jan Roelof van der Meer, Nina Buffi

Living bacteria or yeast cells are frequently used as bioreporters for the detection of specific chemical analytes or conditions of sample toxicity. In particular, bacteria or yeast equipped with synthetic gene circuitry that allows the production of a rel ...

Royal Society of Chemistry2016

Creation of cell aggregates by dielectrophoresis for the in vitro study of electrochemotherapy

Philippe Renaud, Jonathan Bastien Cottet

2016

Multimodal stimulus coding by a gustatory sensory neuron in Drosophila larvae

Philippe Renaud

Accurate perception of taste information is crucial for animal survival. In adult Drosophila, gustatory receptor neurons (GRNs) perceive chemical stimuli of one specific gustatory modality associated with a stereotyped behavioural response, such as aversio ...

Nature Publishing Group2016

Cell-Imprinted Substrates Modulate Differentiation, Redifferentiation, and Transdifferentiation

Philippe Renaud, Arnaud Bertsch, Morteza Mahmoudi, Shahin Bonakdar, Leila Montazeri, Mojtaba Taghipoor, Omid Mashinchian

Differentiation of stem cells into mature cells through the use of physical approaches is of great interest. Here, we prepared smart nanoenvironments by cell-imprinted substrates based on chondrocytes, tenocytes, and semifibroblasts as templates and demons ...

Amer Chemical Soc2016

Neural probe combining microelectrodes and a droplet-based microdialysis collection system for high temporal resolution sampling

Philippe Renaud, Arnaud Bertsch, Guillaume Cédric Yves Petitpierre

We propose a novel neural probe which combines microfluidic channels with recording and stimulation electrodes. The developed microfabrication approach enables the concentration of every active element such as electrodes and the sampling inlet in close pro ...

Royal Society of Chemistry2016

Modification of PDMS to fabricate PLGA microparticles by a double emulsion method in a single microfluidic device

Philippe Renaud, Shahin Bonakdar, Leila Montazeri

We present an easy, durable method to generate a partially hydrophilic/hydrophobic poly(dimethylsiloxane) (PDMS) microfluidic device. The functionality of this device was assessed in a double flow focusing design to fabricate core–shell structured poly(lac ...

Royal Society of Chemistry2016

Fabrication of nanoporous membranes through silicon templates : two different approaches

Philippe Renaud, Arnaud Bertsch, Stefano Silvio Giovanni Varricchio, Niccolo Piacentini

We present here a novel approach to fabricate nanoporous membranes based on the use of sacrificial template structures to individually define pore parameters such as geometry, shape, and placement. Based on this rationale two different nano-fabrication met ...

2016

Device and method for testing a material response to a compound

Philippe Renaud, Robert Meissner

Device for testing a material response, such as a tissue response, to a compound; said device comprising material impedance measuring means which are adapted to measure the material impedance at the compound action site. ...

2015

Thermal gate, a new tool for ionic transport control inside nanochannels

Philippe Renaud, Arnaud Bertsch, Mojtaba Taghipoor

Transport of ionic species solvated in electrolytes depends on temperature. This dependence is much stronger in nanofluidics than large scale since the surface charge also varies with temperature. In this work, we introduce a new tool for the modulation of ...

IEEE2015

A Simple and Reliable PDMS and SU-8 Irreversible Bonding Method and Its Application on a Microfluidic-MEA Device for Neuroscience Research

Marc Olivier Heuschkel, Philippe Renaud, Arnaud Bertsch, Patrick Fraering, Yufei Ren, Sébastien Mosser, Shun-Ho Huang, Jingjing Chen

Polydimethylsiloxane (PDMS) and SU-8 are currently two very commonly used polymeric materials in the microfluidics field for biological applications. However; there is a pressing need to find a simple, reliable, irreversible bonding method between these tw ...

MDPI2015

Mimicking Alzheimer's disease spreading via an integrated microfluidics-MEA device in vitro

Marc Olivier Heuschkel, Philippe Renaud, Patrick Fraering, Yufei Ren, Sébastien Mosser, Jingjing Chen

2015

Smart Knee Prosthesis for Orthopedic Surgery: the implantable and wearable Measurement System

Kamiar Aminian, Philippe Renaud, David Forchelet, Arash Arami

Recent advances in remote powering and telemetry permitted the use of sensors inside body. A few studies have been already done on smart knee prostheses, but all focused on monitoring the in-vivo contact forces and moments. A smart design, compatible with ...

2015

Molecular Dynamics and Monte Carlo simulations resolve apparent diffusion rate differences for proteins confined in nanochannels

Philippe Renaud, Nazar Ileri

We use Molecular Dynamics and Monte Carlo simulations to examine molecular transport phenomena in nanochannels, explaining four orders of magnitude difference in wheat germ agglutinin (WGA) protein diffusion rates observed by fluorescence correlation spect ...

Elsevier2015

Integration of 2D and 3D Thin Film Glassy Carbon Electrode Arrays for Electrochemical Dopamine Sensing in Flexible Neuroelectronic Implants

Philippe Renaud, André Mercanzini, Jules John Vandersarl

Here we present the development and characterization of a flexible implantable neural probe with glassy carbon electrode arrays. The use of carbon electrodes allows for these devices to be used as chemical sensors, in addition to their typical use as elect ...

Wiley-Blackwell2015

Detection of Alzheimer’s disease amyloid-beta plaque deposition by deep brain impedance profiling

Philippe Renaud, Patrick Fraering, Pierre Joris, Sébastien Mosser, Amélie Barbara Hildegarde Béduer

OBJECTIVE: Alzheimer disease (AD) is the most common form of neurodegenerative disease in elderly people. Toxic brain amyloid-beta (ASS) aggregates and ensuing cell death are believed to play a central role in the pathogenesis of the disease. In this study ...

Iop Publishing Ltd2015

On-chip synthesis of fine-tuned bone-seeking hybrid nanoparticles

Philippe Renaud, Arnaud Bertsch, Morteza Mahmoudi, Mohammad Mahdi Hasani-Sadrabadi

Aims: Here we report a one-step approach for reproducible synthesis of finely tuned targeting multifunctional hybrid nanoparticles (HNPs). Materials & methods: A microfluidic-assisted method was employed for controlled nanoprecipitation of bisphosphonate-c ...

Future Medicine Ltd2015

Special Issue: 15 Years of SU8 as MEMS Material

Philippe Renaud, Arnaud Bertsch

MDPI2015

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