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Philippe Renaud

Cette personne a quitté l’EPFL

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Publications associées (301)

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Microfluidic patterning of alginate hydrogels

Philippe Renaud

In this article the authors present techniques which allow the microfluidic design of alginate microgels with layer composition on a chip. The hydrogel is created by combining two laminar flows of the gel precursor solutions-a calcium solution and an algin ...

American Vacuum Society2007

Dielectrophoresis-based purification of antibiotic-treated bacterial subpopulations

Philippe Renaud, John McKinney, Neeraj Dhar, Rodrigo Martinez Duarte, Meltem Elitas

Persistence of bacteria during antibiotic therapy is a widespread phenomenon, of particular importance in refractory mycobacterial infections such as leprosy and tuberculosis. Persistence is characterized by the phenotypic tolerance of a subpopulation of b ...

Royal Soc Chemistry2014

Dielectrophoresis as a single cell characterization method for bacteria

Philippe Renaud, John McKinney, Neeraj Dhar, Thomas Michael Braschler, Ana Valero

Real-time, quantitative characterization of cells at single-cell resolution, particularly while maintain- ing their intrinsic properties and without affecting cellular processes, is of primary importance in modern biological assays. Dielectrophoresis is a ...

Iop Publishing Ltd2017

Label-free detection of Babesia bovis infected red blood cells using impedance spectroscopy on microfabricated flow cytometer

Philippe Renaud, Thomas Michael Braschler, Nicolas Demierre

Impedance spectroscopy is a powerful tool for label-free analysis and characterisation of living cells. In this work, we achieved the detection of Babesia bovis infected red blood cells using impedance spectroscopy on a microfabricated flow cytometer. The ...

2007

Co-pathological states of tau proteins in a 3D micropatterned neural cell culture

Serena Brando, Philippe Renaud, Anja Kunze, Robert Meissner

In vitro studies of Alzheimer’s disease are based on homogenously seeded neural cells. These studies reveal molecular pathway mechanism related to neurite degeneration, but they cannot analyze interactions between diseased and healthy cells. Furthermore, t ...

2011

On-Chip Fabrication of Paclitaxel-Loaded Chitosan Nanoparticles for Cancer Therapeutics

Philippe Renaud, Arnaud Bertsch, Mohammad Mahdi Hasani-Sadrabadi, Jules John Vandersarl

The use of solvent-free microfluidics to fine-tune the physical and chemical properties of chitosan nanoparticles for drug delivery is demonstrated. Nanoparticle self-assembly is driven by pH changes in a water environment, which increases biocompatibility ...

Wiley-Blackwell2014

Tunable optical filter of porous silicon as key component for a MEMS spectrometer

Philippe Renaud, Gerhard Lammel, Sandra Schweizer

We present a microspectrometer based on a tunable interference filter for infrared or visible light that scans the desired part of the spectrum within milliseconds. A single pixel detector measures serially the intensity at selected wavelengths. This conce ...

Institute of Electrical and Electronics Engineers2002

Two-dimensional thermally actuated optical microprojection

Philippe Renaud, Gerhard Lammel, Sandra Schweizer

A dual-axis, raster-scanning laser display based on a monolithic micromachined scanner is presented. The scanner consists of a mirror located at the end of a thermally actuated bimorph beam. The novelty of the device is that the two orthogonal angular moti ...

Elsevier2000

Ionic transport phenomena in nanofluidics: Experimental and theoretical study of the exclusion-enrichment effect on a chip

Philippe Renaud, Reto Bruno Schoch

In nanometer-sized apertures with charged surfaces, the extension of the electrical double layer results in the electrostatic exclusion of co-ions and enrichment in counterions, which affects the permselectivity of such structures. A modeling of this pheno ...

American Chemical Society (ACS)2005

Method for fabricating micromirror for barcode reader, involves forming holes having diameter less than width of arms on both side of micromirror and wafer and on edges of region separating wafer and micromirror by etching arms

Philippe Renaud, Nicolas Abelé

A method for fabricating a micromirror in a wafer, including the steps of: depositing and etching layers forming two arms; etching the wafer such that in the back face only a thin portion of the wafer remains in the region of formation of the micromirror a ...

2010

Development and studies of a novel microfabricated radiation hard scintillation particle detector with high spatial resolution

Philippe Renaud, Alessandro Mapelli, Sébastien Jiguet

A novel scintillation detector is being developed with standard microfabrication techniques. It consists of a dense array of scintillating waveguides obtained by filling microfluidic channels with an organic liquid scintillator. Such a microfluidic device ...

2009

Neurite guidance through 3D hydrogel layers in a microfluidic environment

Philippe Renaud, Anja Kunze, Robert Meissner

Neuronal cell culture models in vitro are often restricted to 2D surfaces. Engineering the complexity of the neuronal microenvironment in microfluidic systems can help to generate more tissue like cultures. We have developed a new neuronal cell culturing s ...

2010

Direct Measurement of Effective Diffusion Coefficients in Nanochannels Using Steady-State Dispersion Effects

Philippe Renaud, Arnaud Bertsch, Nicolas Durand

We present a method to measure effective diffusion coefficients of fluorescently labeled molecules inside a nanofluidic system. Molecules with small diffusion coefficients show a larger lateral dispersion than highly diffusive species, which is counterintu ...

American Institute of Physics2007

Focusing and continuous separation of cells in a microfluidic device using lateral dielectrophoresis

Philippe Renaud, Thomas Michael Braschler, Nicolas Demierre, Randoald Müller

We have fabricated a microfluidic device based on a novel geometrical arrangement of lateral metal electrodes and a patterned insulator. Our device combines the concept of insulator-based “electrodeless” dielectrophoresis with multiple frequencies to achie ...

Elsevier2008

Microelectrical impedance tomography for biophysical characterization of thin film biomaterials

Philippe Renaud, Olof Pontus Linderholm, Reto Bruno Schoch

We present a new method for measuring the electrical resistivities of a stratified sample of thin biomaterials or tissue layers. The presented technique makes use of impedance measurements between It pairs of electrodes separated by varying distances. The ...

2003

Combining multiple optical trapping with microflow manipulation for the rapid bioanalytics on microparticles in a chip

Philippe Renaud, René Salathé, Guy Delacrétaz, Fabrice Merenda, Johann Rohner

An array of four independent laser traps is combined with a polydimethylsiloxane microfluidic chip to form a very compact system allowing parallel processing of biological objects. Strong three dimensional trapping allows holding objects such as functional ...

American Institute of Physics2007

SU-8 as a Material for Microfabricated Particle Physics Detectors

Philippe Renaud, Sébastien Jiguet, Alessandro Mapelli, Pietro Maoddi

Several recent detector technologies developed for particle physics applications are based on microfabricated structures. Detectors built with this approach generally exhibit the overall best performance in terms of spatial and time resolution. Many proper ...

MDPI2014

Device for dispensing microfluidic droplets, particularly for cytometry

Philippe Renaud

The invention relates to a device for dispensing droplets comprising a first channel (8, 10), known as the main channel, for circulating a first liquid flow, a second channel (12, 13) for circulating fluid, forming an intersection area (27) with the first ...

2005

On-Chip Flow Cytometry

Philippe Renaud, Ana Valero

Springer Netherlands2016

Assessment on Enucleated Pig Eyes of a Minimally Invasive Contact Lens Sensor for IOP Monitoring

Philippe Renaud, Arnaud Bertsch, André Mermoud, Matteo Leonardi

2007