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Horst Vogel

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Related publications (116)

Measurement of exclusive ρ+ρ- production in mid-virtuality two-photon interactions and study of the γγ* → ρρ process at LEP

Eduardo Sanchez, Horst Vogel, Aurelio Bay, Jian Zhao, Liang Sun, Qian Wang, Zhirui Xu, Matthias Weber, Ji Hyun Kim, Werner Lustermann, Xiao Wang, Zheng Wang

Exclusive ρ+ρ- production in two-photon collisions between a quasi-real photon, γ, and a mid-virtuality photon, γ*, is studied with data collected at LEP at centre-of-mass energies 183 GeV≤√s≤209 GeV with a total integrated luminosity of 684.8 pb-1. The cr ...

2005

Measurement of the photon structure function F2 γ with the L3 detector at LEP

Eduardo Sanchez, Horst Vogel, Aurelio Bay, Jian Zhao, Liang Sun, Qian Wang, Zhirui Xu, Matthias Weber, Ji Hyun Kim, Werner Lustermann, Xiao Wang, Zheng Wang

The e+e-→e+e-hadrons reaction, where one of the two electrons is detected in a low polar-angle calorimeter, is analysed in order to measure the hadronic photon structure function F2 γ. The full high-energy and high-luminosity data set, collected with the L ...

2005

Impedance spectroscopy of ion channels in tethered lipid bilayers

Horst Vogel, Samuel Terrettaz

A review. The efficient anal. of the function of ion channels is an important task in many different fields ranging from (bio)analytics and drug-screening to nanoelectronics. Here, the modulation of the channel activity of a synthetic ligand gated ion chan ...

2005

Pumping of mammalian cells with a nozzle-diffuser micropump

Christophe Yamahata, Horst Vogel, Martinus Gijs, Caroline Vandevyver, Paulina Izewska, Frédéric Lacharme

We discuss the successful transport of jurkat cells and 5D10 hybridoma cells using a reciprocating micropump with nozzle-diffuser elements. The effect of the pumping action on cell viability and proliferation, as well as on the damaging of cellular membran ...

Royal Society of Chemistry2005

CD8+ Cytotoxic T Lymphocyte Activation by Soluble Major Histocompatibility Complex-Peptide Dimers

Horst Vogel, Jean-Manuel Segura, Bruno Meyer, Olivier Michielin

CD8+ cytotoxic T lymphocyte (CTL) can recognize and kill target cells that express only a few cognate major histocompatibility complex class I-peptide (pMHC) complexes. To better understand the mol. basis of this sensitive recognition process, the authors ...

2005

Cellulose model surface

Horst Vogel, Thierry Stora, Mahtab Varnous

The invention relates to an isotropic cellulose film deposited on an inorg. support layer. The invention also relates to a process for manufg. such cellulose films as well as an anal. cell comprising such deposited films. The cellulose film is particularly ...

(Firmenich S. A., Switz.).2005

Investigating cellular signaling reactions in single attoliter vesicles

Rudolf Hovius, Horst Vogel, Horst Pick, Erwin Ilegems

Understanding cellular signaling mediated by cell surface receptors is key to modern biomedical research and drug development. The discovery of a growing no. of potential mol. targets and therapeutic compds. requires downscaling and accelerated functional ...

2005

Diffusion-Time Distribution Analysis Reveals Characteristic Ligand-Dependent Interaction Patterns of Nuclear Receptors in Living Cells

Horst Vogel, Horst Pick, Hanna Jankevics, Paulina Izewska

Nuclear receptors initiate transcription, interact with regulatory proteins, and are influenced by hormones, drugs, and pollutants. Herein, we discover ligand-specific mobility patterns of human estrogen receptor-a (ER) in living cells using diffusion-time ...

2005

Synthesis of nanoscopic optical fibers using lipid membranes as templates

Rudolf Hovius, Pierre Stadelmann, Horst Vogel, Dimitrios Stamou, Marinela Gjoni Boillat, Jean-Manuel Segura, Gopakumar Gopalakrishnan, Kurt Schenk, Cédric Gaillard

High-aspect-ratio, monocryst. Cd chloride nanowires doped with fluorescent CdS nanoparticles were synthesized using planar lipid membranes as templates. Cd2+ ions bound to the lipid bilayers (a) are released at low pH to the nanometer-sized, interlamellar ...

Wiley-VCH Verlag GmbH2005

CD8 kinetically promotes ligand binding to the T-cell antigen receptor

Horst Vogel

The mechanism of CD8 cooperation with the TCR in antigen recognition was studied on live T cells. Fluorescence correlation measurements yielded evidence of the presence of two TCR and CD8 subpopulations with different lateral diffusion rate consts. Indepen ...

2005

Investigating the function of ion channels in tethered lipid membranes by impedance spectroscopy

Horst Vogel, Samuel Terrettaz

A review. The function of biol. important ion channels can be measured in supported lipid membranes by impedance spectroscopy. This approach offers substantial advantages over traditional electrophysiol. measurements. In this article, we present an overvie ...

2005

Ligand binding transmits conformational changes across the membrane-spanning region to the intracellular side of the 5-HT3 serotonin receptor

Horst Vogel, Horst Pick, Erwin Ilegems, Cédric Deluz

Conformational changes of channel activation: Five enhanced green fluorescent protein (EGFP) mols. (green cylinders) were integrated into the intracellular part of the homopentameric ionotropic 5-HT3 receptor. This allowed the detection of extracellular bi ...

2005

Lipid-coated nanocrystals as multifunctionalized luminescent scaffolds for supramolecular biological assemblies

Rudolf Hovius, Ravindranathan Thampi, Horst Vogel

Nanometer light source: Interaction between high-affinity binding sites on lipid-coated nanocrystals (NCs) and different proteins enables the controlled formation of supramol. nanostructures on micropatterned surfaces. The NCs serve as local light sources ...

Wiley-VCH Verlag GmbH2005

Investigating cellular signalling at the nanometer and attoliter scale

Horst Vogel

Spatial compartmentalisation is a prerequisite for the creation of living matter. Without the existence of clearly defined borders, differentiation and diversity at the cellular level would not be possible. Most scientific disciplines that deal with dissol ...

2005

Kinetics of the initial steps of G protein-coupled receptor-mediated cellular signaling revealed by single-molecule imaging

Horst Vogel, Bruno Meyer

We report on an in vivo single-mol. study of the signaling kinetics of G protein-coupled receptors (GPCR) performed using the neurokinin 1 receptor (NK1R) as a representative member. The NK1R signaling cascade is triggered by the specific binding of a fluo ...

2005

Reversible sequential-binding probe receptor-ligand interactions in single cells

Rudolf Hovius, Horst Vogel, Marinela Gjoni Boillat, Jean-Manuel Segura, Christoph Schreiter

With the reversible sequential (ReSeq) binding assay, we present a novel approach for the ultrasensitive profiling of receptor function in single living cells. This assay is based on the repetitive application of fluorescent ligands that have fast assocn.- ...

2005

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