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Sandro Carrara

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Publications associées (297)

New Measurement Method in Drug Sensing by Direct Total-Charge Detection in Voltammetry

Sandro Carrara, Danilo Demarchi, José David González Martínez, Simone Aiassa

Electrochemical biosensors are promoting point-of-care and wearable instrumentation due to their high versatility in measuring human metabolites. There is a considerable number of biological compounds that can be detected and measured through voltammetry b ...

IEEE2020

Pencil Graphite Needle-Shaped Biosensor for Anaesthetic Monitoring in Human Serum

Sandro Carrara, Danilo Demarchi, Simone Aiassa

Direct and online continuous monitoring of anaesthetic intake by the patient's blood stream improves practices in the critical procedure of anaesthesia. Several systems have been proposed to address this challenge. Electrochemical techniques are highly app ...

IEEE2020

A 3D printed wearable device for sweat analysis

Sandro Carrara, Mahshid Alsadat Padash

This work presents a wearable microfluidic device for sweat analysis. The purpose of this device is to collect sweat from the skin and convey it to the sensor. The device is printed by a 3D printer with Multi-Jet Modelling (MJM) technology using flexible m ...

IEEE2020

Biosensors for Bimolecular Computing: a Review and Future Perspectives

Sandro Carrara, Danilo Demarchi, Simone Aiassa

Biomolecular computing is the field of engineering where computation, storage, communication, and coding are obtained by exploiting interactions between biomolecules, especially DNA, RNA, and enzymes. They are a promising solution in a long-term vision, br ...

SPRINGER2020

Electrochemical determination of nicotine in smokers' sweat

Sandro Carrara, Tugba Kilic

In this work, we report the demonstration of the capability of electrochemical sensors to provide measurements directly on the sweat of volunteers to successfully discriminate heavy smokers by light ones. Since its importance as pharmaceutical treatment-ag ...

ELSEVIER2020

Continuous monitoring of propofol in human serum with fouling compensation by support vector classifier

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Francesco Grassi, Francesca Criscuolo, Simone Aiassa, Tiberiu Totu, Gabriele Sandri

We present a new method for electrochemical sensing, which compensates the fouling effect of propofol through machine learning (ML) model. Direct and continuous monitoring of propofol is crucial in the development of automatic systems for control of drug i ...

Elsevier2020

Memristive Biosensors based on Full-size Antibodies and Antibody Fragments

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki, Sébastien Naus

For the first time memristive biosensors developed by the incorporation of scAbs (single-chain antibody fragments) enabling label-free detection of free Prostate Specific Antigen (fPSA) for early-stage detection of prostate cancer (PC) are reported. In add ...

2019

Multi-panel, on-single-chip Memristive Biosensing

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki, Abuduwaili Tuoheti, Danilo Demarchi

Memristive biosensors have demonstrated excellent capabilities for ultrasensitive bio-detection. In the present work, memristive biosensing chips are designed, fabricated and implemented in a for the first time presented multi-panel on-chip detection for d ...

2019

Supplementary Material for "Optimized Sampling Rate for Voltammetry-Based Electrochemical Sensing in Wearable and IoT Applications"

Sandro Carrara, Danilo Demarchi, Simone Aiassa

The Voltammetry-Based Sensing (VBS) methods are extremely interesting due to high specificity in several biochemical applications. Several considerations can be applied to use this method to measure different analytes, and implement efficient and optimized ...

2019

Optimized Sampling Rate for Voltammetry-Based Electrochemical Sensing in Wearable and IoT Applications

Sandro Carrara, Danilo Demarchi, Simone Aiassa

The recent advancements in electrochemical measurements are guiding the development of new platforms for in situ point-of-care monitoring of human-metabolite, markers, and drugs. Despite this, the application of voltammetry-based sensing (VBS) techniques i ...

2019

Direct and catalyst-free growth of vertically-stacked graphene-based structures for enhanced drug sensing

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi

In this work, a complete study is carried out for the optimised, direct and catalyst-free growth of vertically-stacked graphene-based structures targeting at improved performance drug monitoring. The nanostructures, ultimately forming a honeycomb network o ...

IEEE2019

Integration Methods of Cyclodextrins on Gold and Carbon Electrodes for Electrochemical Sensors

Sandro Carrara, Irene Taurino, Maria Antonietta Casulli

Cyclodextrins (CDs) are oligosaccharides composed of six (α), seven (β) or eight (γ) glucose units. Their inner hydrophobic cavity and hydrophilic external surface enable the formation of the “host-guest inclusion complex” with different organic or inorgan ...

2019

Fast Procedures for the Electrodeposition of Platinum Nanostructures on Miniaturized Electrodes for Improved Ion Sensing

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Nanostructured materials have attracted considerable interest over the last few decades to enhance sensing capabilities thanks to their unique properties and large surface area. In particular, noble metal nanostructures offer several advantages including h ...

2019

Nanowire Sensors in Cancer

Sandro Carrara

In 2006, the group of Dr C.M. Lieber pioneered the field of nanowire sensors by fabricating devices for the ultra-sensitive label-free detection of biological macromolecules. Since then, nanowire sensors have demonstrated their ability to detect cancer-ass ...

2019

All-solid-state Reference Electrodes for analytical applications

Giovanni De Micheli, Sandro Carrara, Francesca Criscuolo

2019

Multi-Target Electrolyte Sensing Front-End for Wearable Physical Monitoring

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Francesca Criscuolo

Wearable physiology is an expanding field, especially for sports applications that steadily require an accurate monitoring of the physical status of athletes. This work presents the co-design and the realization of an hardware front-end that enables multi- ...

IEEE2019

Flexible sweat sensors for non-invasive optimization of lithium dose in psychiatric disorders

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium is the main mood stabilizer in bipolar disorders and other psychiatric conditions. However, lithium levels in blood must be monitored frequently during therapies because of its narrow therapeutic range. For this reason the patients, whose quality o ...

IEEE2019

Live Demonstration: Quasi-Digital Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Danilo Demarchi, Francesco Grassi, Simone Aiassa

The live demonstration presents the innovative concept of a portable pen-device able to sense anaesthetic compounds over time for improved anaesthesiology practice. A custom Printed Circuit Board (PCB) manage in the event-based quasi-digital domain the sam ...

IEEE2019

Electrochemical detection of different p53 conformations by using nanostructured surfaces

Sandro Carrara, Francesca Stradolini, Sarah Tonello

Protein electrochemistry represents a powerful technique for investigating the function and structure of proteins. Currently available biochemical assays provide limited information related to the conformational state of proteins and high costs. This work ...

Springer Nature2019

Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Francesca Stradolini, Abuduwaili Tuoheti, Danilo Demarchi, Simone Aiassa

Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commercial tools able to ...

IEEE2019

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