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Sandro Carrara

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Publications associées (297)

Gold and silver bio/nano-hybrids-based electrochemical immunosensor for ultrasensitive detection of carcinoembryonic antigen

Sandro Carrara, Sattar Akbari Nakhjavani, Hadi Afsharan

Carcinoembryonic antigen (CEA) is an important oncomarker for the detection of breast cancer. For ultra-sensitive sensing of CEA with great specificity and accuracy, an innovative and reliable electrochemical immunosensor was developed using various nano-h ...

2019

Highly-stable Li + ion-selective electrodes based on noble metal nanostructured layers as solid-contacts

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Stradolini, Francesca Criscuolo

Nowadays the development of stable and highly efficient Solid-Contact Ion-Selective Electrodes (SC-ISEs) attracts much attention in the research community because of the great expansion of portable analytical devices. In this work, we present highly stable ...

2018

Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Nima Aliakbarinodehi, Ioulia Tzouvadaki, Francesca Stradolini, Sattar Akbari Nakhjavani

Nano-materials are highly exploited to enhance sensing performance of electrochemical electrodes by increasing the Electro-Active Surface Area (EASA). In this work, an analytical calculation of the deposited EASA is presented and experimentally validated b ...

2018

Mining the Potential of Label-Free Biosensors for In Vitro Antipsychotic Drug Screening

Sandro Carrara, Hatice Altug, Maria Soler Aznar, Tugba Kilic

The pharmaceutical industry is facing enormous challenges due to high drug attribution rates. For the past decades, novel methods have been developed for safety and efficacy testing, as well as for improving early development stages. In vitro screening met ...

2018

Graphene nanowalls for high-performance chemotherapeutic drug sensing and anti-fouling properties

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi, Ioulia Tzouvadaki

Improved sensitivity and continuous monitoring of therapeutic compounds are two of the most highlighted concerns for the treatment of malignant diseases, such as cancer. We demonstrated ultrasensitive screening of etoposide, a therapeutic compound widely-u ...

2018

Label-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells

Philippe Renaud, Sandro Carrara, Tugba Kilic, Ana Teresa De Sousa Valinhas

Nanoscale extracellular vesicles (EVs) including exosomes (50–150 nm membrane particles) have emerged as promising cancer biomarkers due to the carried genetic information about the parental cells. However the sensitive detection of these vesicles remains ...

Nature Research2018

Organs-on-chip monitoring: sensors and other strategies

Philippe Renaud, Sandro Carrara, Fatemeh Navaee, Francesca Stradolini, Tugba Kilic

As a paradigm shifting player of tissue engineering, organs-on-chips (OOCs) are considered to hold great potential for future “clinical trials on chip” as well as a step forward to design personalized medicine. Despite all ethical concerns raised by commun ...

2018

Portable Memristive Biosensing System as Effective Point-of-Care Device for Cancer Diagnostics

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki, Abuduwaili Tuoheti, Danilo Demarchi

Memristive biosensors have been proved as excellent candidates for ultrasensitive biosensing. In this work, a novel portable bio-detection system based on memristive biosensors is designed, developed and tested for providing a significantly fast, automatic ...

IEEE2018

Enhanced Sensing of Interleukin 8 by Stripping Voltammetry: Carbon Nanotubes versus Fullerene

Sandro Carrara, Tugba Kilic, Sarah Tonello

The ability to detect protein biomarkers at a subnanomolar level represents a pervasive challenge in order to bring a significant improvement in early diagnosis or progression of pato-physiological processes. To this aim, Screen Printed Electrochemical Sen ...

SPRINGER-VERLAG SINGAPORE PTE LTD2018

A novel electrochemical sensor for non-invasive monitoring of lithium levels in mood disorders

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium is the main drug for the treatment of mood disorders. Due to its narrow therapeutic window, Therapeutic Drug Monitoring (TDM) is a norm during therapy in order to avoid adverse effects. Consequently, patients are obliged to frequent check-ups in ho ...

2018

Highly sensitive enzymatic MWCNTs-based biosensors for detection of abiraterone in human serum

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi

A highly-sensitive enzymatic biosensor is successfully experimented for detection of abiraterone in human serum with significance in personalized medicine and point-of-care chemotherapy of patients with metastatic prostate cancer. The dynamic range and lim ...

2018

Long-term Monitoring of Propofol and Fouling Effect on Pencil Graphite Electrodes

Giovanni De Micheli, Sandro Carrara, Francesca Stradolini

2018

An IoT Solution for Online Monitoring of Anesthetics in Human Serum Based on an Integrated Fluidic Bioelectronic System

Giovanni De Micheli, Sandro Carrara, Francesca Stradolini, Abuduwaili Tuoheti, Danilo Demarchi, Tugba Kilic, Sofia Lydia Ntella, Nadia Tamburrano, Zijian Huang

In this paper, we present the design, the implementation and the validation of a novel Internet of Things (IoT) drug monitoring system for the online continuous and simultaneous detection of two main anesthetics, e.g., propofol and paracetamol, in undilute ...

2018

IoT for Telemedicine Practices enabled by an Android (TM) Application with Cloud System Integration

Sandro Carrara, Thiébaud Modoux, Francesca Stradolini, Abuduwaili Tuoheti, Danilo Demarchi, Nadia Tamburrano

Connected medical devices are already paving the way towards the realization of Smart Hospitals where patient care is improved thanks to Internet of Things (IoT) solutions. Following this trend, in this paper we propose an IoT cloud-based network for anest ...

IEEE2018

A Flexible Front-End for Wearable Electrochemical Sensing

Giovanni De Micheli, Sandro Carrara, Francesca Stradolini, Abuduwaili Tuoheti, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Tugba Kilic, Francesca Criscuolo, Lucia Lobello

This work presents the design and the realization of a flexible front-end circuitry for electrochemical sensing with wearable devices. The hardware combines readout circuitry for amperometric and Open Circuit Potential (OCP) measurements. The sensing platf ...

IEEE2018

Fouling-resistant pencil graphite electrode

Sandro Carrara, Francesca Stradolini, Tugba Kilic

A Pencil Graphite Electrode (PGE) is herein disclosed. The electrode is characterized by a reduced content in graphite and an increased content in clay of the composite material composing it compared to the prior art PGEs. In particular, the PGE according ...

2018

Special Issue on Selected Papers From IEEE BioCAS 2017

Sandro Carrara

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2018

A novel psychoanalytical approach: An electrochemical ligand-binding assay to screen antipsychotics

Sandro Carrara, Tugba Kilic

Schizophrenia treatment may see a paradigm shift due to development of new atypical antipsychotic drugs (APDs), with better tolerability due to more selective dopamine (DA) receptor blockade. Monitoring of these APD candidates in biological fluids is of gr ...

2018

Raspberry-Pi based system for propofol monitoring

Sandro Carrara, Francesca Stradolini, Abuduwaili Tuoheti, Danilo Demarchi, Tugba Kilic

Induction of anesthesia with propofol is a largely adopted technique in hospital environments. The correct dosage of this compound is essential to avoid under- or over-anesthesia that may result in serious side-effects. Therefore, in clinical settings, lon ...

ELSEVIER SCIENCE BV2018

microRNA biosensors: Opportunities and challenges among conventional and commercially available techniques

Sandro Carrara, Tugba Kilic

As being the most extensively studied, non-coding, evolutionary conserved, post-transcriptional gene regulators of genome, microRNAs (miRNAs) have taken great attention among various disciplines due to their important roles in biological processes and link ...

2018

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