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Publications associées (296)

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Empowering Low-Cost CMOS Cameras by Image Processing to Reach Comparable Results with Costly CCDs

Giovanni De Micheli, Yusuf Leblebici, Sandro Carrara, Julien Michel Ghaye, Gözen Köklü

Despite the huge research effort to improve the performance of the complementary metal oxide semiconductor (CMOS) image sensors, charge-coupled devices (CCDs) still dominate the cell biology-related conventional fluorescence microscopic imaging market wher ...

2013

Design of an integrated low-noise read-out system for DNA capacitive sensors

Sandro Carrara

This paper presents an electronic system for a fast DNA label-less detection. The sensitivity of the capacitive sensor in use is improved by depositing an insulating self-assembled monolayer (SAM) over the golden electrodes. The capacitance shift due to th ...

Elsevier2009

Thermal and humidity monitoring in "Cold" silicon-based high energy physics detectors

Sandro Carrara, Amar Kapic

As high readout channel density and compact design become the norm for HEP detectors so is the detector cooling at temperatures below the experimental site dewpoint. This increases the importance of humidity and temperature monitoring systems that are also ...

IOP Publishing Ltd2023

Comparative study of three lactate oxidases from Aerococcus viridans for biosensing applications

Giovanni De Micheli, Sandro Carrara, Irene Taurino

A comparison between engineered and commercially available L-lactate oxidases from Aerococcus viridans was conducted for biosensing applications. Enzymes were adsorbed onto the surfaces of graphite electrodes modified with multi-walled carbon nanotubes. Th ...

Elsevier2013

Preliminary Study of a Flexible Printed Multi-Sensing Platform for Electromyography and Lactate Measuring during Rehabilitation

Sandro Carrara

Real-time measure of muscular fatigue during physical exercise is highly demanded in fields as rehabilitation and physiotherapy, both hospital and home-based. In addition to the well-accepted features extracted from EMG measurements, an increasing interest ...

IEEE2021

Electrodes for Paracetamol Sensing Modified with Bismuth Oxide and Oxynitrate Heterostructures: An Experimental and Computational Study

Sandro Carrara

In this work, novel platforms for paracetamol sensing were developed by the deposition of Bi2O3, Bi5O7NO3 and their heterostructures onto screen-printed carbon-paste electrodes. An easy and scalable solid state synthesis route was employed, and by setting ...

MDPI2021

Laser-Induced Graphene on Chitosan: An Enabling Technology for Sustainable Resistive Humidity Sensors

Sandro Carrara, Johanna Zikulnig

The development and characterization of resistive humidity sensors based on Chitosan on a glass substrate is reported. The sensor electrodes are made of laser-induced graphene derived from Chitosan, which represents a sustainability advancement by eliminat ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2023

Graphene nanowalls for high-performance chemotherapeutic drug sensing and anti-fouling properties

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki, Nima Aliakbarinodehi

Improved sensitivity and continuous monitoring of therapeutic compounds are two of the most highlighted concerns for the treatment of malignant diseases, such as cancer. We demonstrated ultrasensitive screening of etoposide, a therapeutic compound widely-u ...

Elsevier2018

An IoT Solution for Online Monitoring of Anesthetics in Human Serum Based on an Integrated Fluidic Bioelectronic System

Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Francesca Stradolini, Tugba Kilic, Sofia Lydia Ntella, Abuduwaili Tuoheti

In this paper, we present the design, the implementation and the validation of a novel Internet of Things (IoT) drug monitoring system for the online continuous and simultaneous detection of two main anesthetics, e.g., propofol and paracetamol, in undilute ...

2018

Circuits Design and Nano-Structured Electrodes for Drugs Monitoring in Personalized Therapy

Giovanni De Micheli, Sandro Carrara, Luca Benini, Andrea Cavallini, Jacopo Olivo

Drug development and personalized therapy require accurate and frequent monitoring of the metabolic response by living tissues to treatments. In case of high risk side effects, e.g. therapies with interfering anti-cancer molecule cocktails, direct monitori ...

IEEE2008

Wireless Monitoring of Endogenous and Exogenous Biomolecules on an Android Interface

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Camilla Baj-Rossi, Francesca Stradolini, Cristina Boero, Grégoire Casimir Joseph Surrel, Stefano Riario

Monitoring patients in intensive care units is generally expensive and time consuming. A prompter medical intervention for those critical patients is a key factor for their safety. Therefore, a system that offers immediate visualization of the monitored da ...

Institute of Electrical and Electronics Engineers2016

microRNA biosensors: Opportunities and challenges among conventional and commercially available techniques

Sandro Carrara, Tugba Kilic

As being the most extensively studied, non-coding, evolutionary conserved, post-transcriptional gene regulators of genome, microRNAs (miRNAs) have taken great attention among various disciplines due to their important roles in biological processes and link ...

2018

The Birth of a New Field: Memristive Sensors. A Review

Sandro Carrara

Over the last 11 years, the field of Memristive Sensors abruptly emerged in literature. The present review paper has the aim to acknowledge such an exciting new field of research as well as to critically review its most significant outcomes. As usual in sc ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Nutrichip: an integrated microfluidic system for in vitro investigation of the immunemodulatory function of dairy products

Martinus Adela Maria Gijs, Sandro Carrara, Paolo Silacci, Flurina Schwander, Hamideh Jafarpoorchekab

We introduce the concept of the NutriChip, a miniaturized artificial human gastrointestinal tract (GIT) for investigating the potential of immuno-modulatory function of dairy food. More specifically, we are investigating the effect of digested milk on immu ...

2011

Surface trap mediated electronic transport in biofunctionalized silicon nanowires

Giovanni De Micheli, Sandro Carrara, Francesca Puppo

Silicon nanowires (SiNWs), fabricated via a top-down approach and then functionalized with biological probes, are used for electrically-based sensing of breast tumor markers. The SiNWs, featuring memristive-like behavior in bare conditions, show, in the pr ...

2016

Unraveling the Effect of the Chemical and Structural Composition of ZnxNi1-xFe2O4 on the Electron Transfer at the Electrochemical Interface

Mallikarjun Madagalam, Sandro Carrara

In order to deepen the understanding of the role of transition metal oxides in electron transfer at the electrochemical interface, the performance of ZnxNi1-xFe2O4 (x = 0, 0.2, 0.4, 0.6, 0.8, 1) nanomaterials in electrochemical sensing is studied. Nanomate ...

WILEY2023

A Linear Approach to Multi-Panel Sensing in Personalized Therapy for Cancer Treatment

Giovanni De Micheli, Sandro Carrara, Camilla Baj-Rossi

In this paper, a new approach for evaluating the performance of a multi-panel biosensor using linear algebra is presented. With a system-level mathematical analysis based on graphs and linear algebra, we formulate a new approach for contributions decouplin ...

Institute of Electrical and Electronics Engineers2013

Simultaneous and Selective Detection of Etoposide and Methotrexate With Single Electrochemical Sensors for Therapeutic Drug Monitoring

Sandro Carrara, Francesca Rodino

Etoposide (ETO) and methotrexate (MTX) are widely used chemotherapy drugs in cancer treatment, targeting specific cellular processes crucial for DNA replication and cell division. Despite their efficacy, both drugs have significant adverse toxic effects du ...

2023

Carbon Nanotubes-Based Electrochemical Sensing for Cell Culture Monitoring

Giovanni De Micheli, Sandro Carrara, Cristina Boero

Monitoring of metabolic compounds, such as glucose and lactate, is extensively reported in literature, especially for clinical purposes. Instead, the application of such technologies for monitoring metabolites in cell cultures has not been explored. From o ...

2010

Implantable devices: the future of blood monitoring? (Editorial)

Giovanni De Micheli, Sandro Carrara, Cristina Boero

Implantable devices can be developed for the simultaneous monitoring of a specific group of key metabolites, identified by more complex techniques, such as mass spectroscopy- or nuclear magnetic -based analysis.. Since there is a strong correlation between ...

2013