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Claudio Bruschini

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Publications associées (180)

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EndoTOFPET-US a High Resolution Endoscopic PET-US Scanner Used for Pancreatic and Prostatic Clinical Exams

Claudio Bruschini

2014

Optical-stack optimization for improved SPAD photon detection efficiency

Edoardo Charbon, Claudio Bruschini, Rolando Ferrini, Arin Can Ülkü, Ivan Michel Antolovic, Scott Anthony Lindner, Ekin Kizilkan, Frédéric Zanella

Single-photon avalanche diodes (SPADs) are direct photon-to-digital detectors that enable scalable arrays with Poisson-limited signal-to-noise ratio and picosecond timing resolution. However, SPAD detectors require a guard-ring structure to prevent lateral ...

2019

CMOS 3D-Stacked FSI Multi-Channel Digital SiPM for Time-of-Flight Vision Applications

Edoardo Charbon, Claudio Bruschini, Francesco Gramuglia, Scott Anthony Lindner, Myung Jae Lee, Andrei Ardelean, Andrada Alexandra Muntean, Esteban Venialgo Araujo

International Image Sensors Society2021

Technology Transfer Bottlenecks and Lessons Learned in Humanitarian Demining EU-funded Research: Analysis & Results from the EC DELVE Project

Claudio Bruschini

2008

EndoTOFPET-US – A Miniaturised Calorimeter for Endoscopic Time-of-Flight Positron Emission Tomography

Claudio Bruschini

IOP2015

EndoTOFPET-US: Multi-modal endoscope for Ultrasound and Time of Flight PET

Claudio Bruschini

IEEE2014

Light- field tomographic fluorescence lifetime imaging microscopy

Edoardo Charbon, Claudio Bruschini, Samuel Burri

Fluorescence lifetime imaging microscopy (FLIM) is a powerful imaging technique that enables the visualization of biological samples at the molecular level by measuring the fluorescence decay rate of fluorescent probes. This provides critical information a ...

National Academy of Sciences2024

Cryogenic Characterization of 28 nm Bulk CMOS Technology for Quantum Computing

Christian Enz, Claudio Bruschini, Arnout Lodewijk M Beckers, Farzan Jazaeri, Andrea Ruffino

This paper presents the first experimental investigation and physical discussion of the cryogenic behavior of a commercial 28 nm bulk CMOS technology. Here we extract the fundamental physical parameters of this technology at 300,77 and 4.2 K based on DC me ...

2017

Massively parallel, real-time multispeckle diffuse correlation spectroscopy using a 500 × 500 SPAD camera

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü, Andrei Ardelean, Paul Mos, Michael Alan Wayne

Diffuse correlation spectroscopy (DCS) is a promising noninvasive technique for monitoring cerebral blood flow and measuring cortex functional activation tasks. Taking multiple parallel measurements has been shown to increase sensitivity, but is not easily ...

2023

Fluorescence lifetime imaging with a megapixel SPAD camera and neural network lifetime estimation

Edoardo Charbon, Claudio Bruschini, Ming-Lo Wu, Kazuhiro Morimoto

Fluorescence lifetime imaging microscopy (FLIM) is a key technology that provides direct insight into cell metabolism, cell dynamics and protein activity. However, determining the lifetimes of different fluorescent proteins requires the detection of a rela ...

NATURE RESEARCH2020

Sub-10 ps Minimum Ionizing Particle Detection With Geiger-Mode APDs

Edoardo Charbon, Claudio Bruschini, Francesco Gramuglia, Emanuele Ripiccini, Ming-Lo Wu

Major advances in silicon pixel detectors, with outstanding timing performance, have recently attracted significant attention in the community. In this work we present and discuss the use of state-of-the-art Geiger-mode APDs, also known as single-photon av ...

FRONTIERS MEDIA SA2022

Photon-Counting Arrays for Time-Resolved Imaging

Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic, Samuel Burri

The paper presents a camera comprising 512 x 128 pixels capable of single-photon detection and gating with a maximum frame rate of 156 kfps. The photon capture is performed through a gated single-photon avalanche diode that generates a digital pulse upon p ...

MDPI2016

Sensor Network Architecture for a Fully Digital and Scalable SPAD based PET System

Edoardo Charbon, Claudio Bruschini

Digital SiPMs in the recent past have emerged as a viable low cost alternative to PMTs providing higher granularity and MRI compatibility. The rich dataset generated by digital SiPM sensors have posed a challenge, especially at the system level when a mult ...

2012

Fluorescence lifetime imaging with a single-photon SPAD array using long overlapping gates: an experimental and theoretical study

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü, Andrei Ardelean

Developing large arrays of single-photon avalanche diodes (SPADs) with on-chip time-correlated single-photon counting (TCSPC) capabilities continues to be a difficult task due to stringent silicon real estate constraints, high data rates and system complex ...

2019

Single-photon avalanche diode imaging sensor for subsurface fluorescence LiDAR

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü

We realized subsurface fluorescence LiDAR with a large format single-photon avalanche diode array capable of localizing and quantifying concentration of fluorescent molecules in heavily scattering media, such as tissue, with submillimeter depth accuracy. ( ...

OPTICAL SOC AMER2021

Light Extraction Enhancement Techniques for Inorganic Scintillators

Edoardo Charbon, Claudio Bruschini, Francesco Gramuglia, Emanuele Ripiccini, Esteban Venialgo Araujo, Simone Frasca

Scintillators play a key role in the detection chain of several applications which rely on the use of ionizing radiation, and it is often mandatory to extract and detect the generated scintillation light as efficiently as possible. Typical inorganic scinti ...

2021

Engineering Breakdown Probability Profile for PDP and DCR Optimization in a SPAD Fabricated in a Standard 55nm BCD Process

Edoardo Charbon, Claudio Bruschini, Francesco Gramuglia, Myung Jae Lee, Ekin Kizilkan, Pouyan Keshavarzian

CMOS Single-Photon Avalanche Diodes (SPADs) have broken into the mainstream by enabling the adoption of imaging, timing, and security technologies in a variety of applications within the consumer, medical and industrial domains. The continued scaling of te ...

2021

Towards video-rate compressive spontaneous Raman imaging using single-photon avalanche diode arrays

Edoardo Charbon, Claudio Bruschini, Samuel Burri

Compressive Raman imaging has emerged as a promising technique to speed up chemical imaging by compressing the data during acquisition. Yet, current scanning imaging speed is fundamentally limited by the sensors pixel dwell times of at best 1µs. Here, we i ...

SPIE2024

CMOS-Based Single-Photon Detectors: Technology and Applications

Edoardo Charbon, Claudio Bruschini, Myung Jae Lee

The goal of this paper is to introduce CMOS-based single-photon detectors in terms of technology and applications. We cover background and recent progress on the detectors and describe emerging applications based on the technology. ...

IEEE2018

Fast Two-Photon Interferometer Capable of Spectral Binning for Quantum Telescopy

Edoardo Charbon, Claudio Bruschini, Samuel Burri, Ermanno Bernasconi

We describe a novel type of two-photon interferometer, capable of spectral binning, for quantum-assisted astrometry. We also demonstrated a single-photon spectrometer with spectral and timing resolutions of 0.1 nm and 50 ps, which can be used for this purp ...

Optical Society of America2023