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Philippe Renaud

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Publications associées (301)

Rapid, Sensitive and Real-Time Multiplexing Platform for the Analysis of Protein and Nucleic-Acid Biomarkers

Philippe Renaud, Nicolas Demierre, Raphaël Tornay, David Bernasconi, Lucienne Lagopoulos

We describe a multiplexing technology, named Evalution, based on novel digitally encoded microparticles in microfluidic channels. Quantitative multiplexing is becoming increasingly important for research and routine clinical diagnostics, but fast, easy-to- ...

Amer Chemical Soc2015

Thermal control of ionic transport and fluid flow in nanofluidic channels

Philippe Renaud, Arnaud Bertsch, Mojtaba Taghipoor

In this work, we report a nanofluidic gating mechanism that uses the thermal effect for modulating the ionic transport inside nanofluidic channels. The control of the ionic transport inside a nanochannel is demonstrated using electrical conductivity. A the ...

2015

A Compressible Scaffold for Minimally Invasive Delivery of Large Intact Neuronal Networks

Philippe Renaud, Thomas Michael Braschler, Patrick Fraering, Oliver Peric, Georg Fantner, Sébastien Mosser, Amélie Barbara Hildegarde Béduer, Sidi Ahmed Bencherif

Millimeter to centimeter-sized injectable neural scaffolds based on macroporous cryogels are presented. The polymer-scaffolds are made from alginate and carboxymethyl-cellulose by a novel simple one-pot cryosynthesis. They allow surgical sterility by means ...

Wiley-VCH Verlag2015

An improved model for predicting electrical conductance in nanochannels

Philippe Renaud, Arnaud Bertsch, Mojtaba Taghipoor

Nanochannel conductance measurements are commonly performed to characterize nanofluidic devices Theoretical analysis and experimental investigations imply that the nanochannel conductance does not follow the macro-scale models. It is generally accepted tha ...

2015

Temperature Sensitivity of Nanochannel Electrical Conductance

Philippe Renaud, Arnaud Bertsch, Mojtaba Taghipoor

Electrical measurement is a widely used technique for the characterization of nanofluidic devices. The electrical conductivity of electrolytes is known to be dependent on temperature. However, the similarity of the temperature sensitivity of the electrical ...

Amer Chemical Soc2015

On-Chip Fabrication of Paclitaxel-Loaded Chitosan Nanoparticles for Cancer Therapeutics

Philippe Renaud, Arnaud Bertsch, Fatemeh Sadat Majedi, Mohammad Mahdi Hasani-Sadrabadi, Shahin Bonakdar, Jules John Vandersarl

The use of solvent-free microfluidics to fine-tune the physical and chemical properties of chitosan nanoparticles for drug delivery is demonstrated. Nanoparticle self-assembly is driven by pH changes in a water environment, which increases biocompatibility ...

Wiley-Blackwell2014

Scintillation detectors based on silicon microfluidic channels

Philippe Renaud, Alessandro Mapelli, Pietro Maoddi

Microfluidic channels obtained by SU-8 photolithography and filled with liquid scintillators were recently demonstrated to be an interesting technology for the implementation of novel particle detectors. The main advantages of this approach are the intrins ...

Institute of Physics2014

Smart instrumentation for determination of ligament stiffness and ligament balance in total knee arthroplasty

Kamiar Aminian, Philippe Renaud, Arnaud Bertsch, Brigitte Jolles-Haeberli, Arash Arami, Willyan Hasenkamp Carreira

Ligament balance is an important and subjective task performed during total knee arthroplasty (TKA) procedure. For this reason, it is desirable to develop instruments to quantitatively assess the soft-tissue balance since excessive imbalance can accelerate ...

Elsevier Sci Ltd2014

Enclosed Electronic System for Force Measurements in Knee Implants

Kamiar Aminian, Philippe Renaud, Arnaud Bertsch, Peter Ryser, Eric Meurville, David Forchelet, Arash Arami, Matteo Simoncini

Total knee arthroplasty is a widely performed surgical technique. Soft tissue force balancing during the operation relies strongly on the experience of the surgeon in equilibrating tension in the collateral ligaments. Little information on the forces in th ...

Mdpi Ag2014

SU-8 as a Material for Microfabricated Particle Physics Detectors

Philippe Renaud, Alessandro Mapelli, Sébastien Jiguet, Pietro Maoddi

Several recent detector technologies developed for particle physics applications are based on microfabricated structures. Detectors built with this approach generally exhibit the overall best performance in terms of spatial and time resolution. Many proper ...

MDPI2014

Fabrication of thermo-responsive nano-valve by grafting-to in melt of poly(N-isopropylacrylamide) onto nanoporous silicon nitride membranes

Philippe Renaud, Raphaël Pugin, Franck Montagne, Alexandre Zenon Ivan Bojko

This article reports the grafting-to in melt of amino and carboxy-terminated poly(N-isopropylacrylamide) (PNIPAM) onto ultrathin nanoporous silicon nitride membranes (NSiNMs) with a mean pore size of 85 +/- 15 nm functionalized respectively with a self-ass ...

Elsevier2014

Accurate resistivity mouse brain mapping using microelectrode arrays

Philippe Renaud, Vincent Delattre, Patrick Fraering, Pierre Joris, Sébastien Mosser, Amélie Barbara Hildegarde Béduer

Electrical impedance spectroscopy measurements were performed in post-mortem mice brains using a flexible probe with an embedded micrometric electrode array. Combined with a peak resistance frequency method this allowed obtaining intrinsic resistivity valu ...

Elsevier2014

Implantable and wearable measurement system for smart knee prosthesis

Kamiar Aminian, Philippe Renaud, David Forchelet, Arash Arami

In this work we present the implantable and wearable measurement system developed for smart knee prostheses monitoring. The kinematic measurement system contains three anisotropic magnetoresistive sensors embedded into the polyethylene part of the prosthes ...

IEEE2014

Compact portable biosensor for arsenic detection in aqueous samples with Escherichia coli bioreporter cells

Philippe Renaud, Harald Van Lintel, Nina Buffi

We present a compact portable biosensor to measure arsenic As(III) concentrations in water using Escherichia coli bioreporter cells. Escherichia coli expresses green fluorescent protein in a linearly dependent manner as a function of the arsenic concentrat ...

Amer Inst Physics2014

Electrical stimulation of the cochlear nucleus with a thin polymer microelectrode array: Designing the next generation auditory brainstem implant

Philippe Renaud, Amélie Anne Guex, Stéphanie Lacour

2014

On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids

Philippe Renaud, Sébastien Jiguet, Pietro Maoddi, Hendrik Georges Deschout

Cell-derived membrane vesicles that are released in biofluids, like blood or saliva, are emerging as potential non-invasive biomarkers for diseases, such as cancer. Techniques capable of measuring the size and concentration of membrane vesicles directly in ...

Royal Soc Chemistry2014

Modeling, Simulation, and Performance Evaluation of a Novel Microfluidic Impedance Cytometer for Morphology-Based Cell Discrimination

Philippe Renaud, Ludovica Colella, Marjan Shaker

The performance of a novel microfluidic impedance cytometer [1] for single-cell analysis is investigated in-silico by means of a finite element model. The main feature of the device is the ability to probe impedance of flowing cells along two orthogonal di ...

Institute of Electrical and Electronics Engineers2014

Biomimetic Pieris rapae’s Nanostructure and Its Use as a Simple Sucrose Sensor

Philippe Renaud, David Vincent Bonzon, Rodrigo Martinez Duarte

iomimetics often provides efficient ways to create a product incorporating novel properties. Here we present the replication of the Pieris rapae butterfly optical structure. This butterfly has white wings with black spots. The white coloration is produced ...

MDPI2014

Dielectrophoresis-based purification of antibiotic-treated bacterial subpopulations

Philippe Renaud, John McKinney, Neeraj Dhar, Meltem Elitas, Rodrigo Martinez Duarte

Persistence of bacteria during antibiotic therapy is a widespread phenomenon, of particular importance in refractory mycobacterial infections such as leprosy and tuberculosis. Persistence is characterized by the phenotypic tolerance of a subpopulation of b ...

Royal Soc Chemistry2014

An impedance-based flow microcytometer for single cell morphology discrimination

Philippe Renaud, Ludovica Colella, Marjan Shaker

Cell shape is a fundamental biological feature, providing specific information about physiological or pathological cellular conditions. Most of the state-of-the-art microfluidic cytometers, however, only allow simple cell analysis, including viability stud ...

Royal Soc Chemistry2014

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