Optical plasmonic trapping towards biological applications in microfluidics

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We introduce a droplet-digital microfluidic recovery system to collect single cells from pooled culture and transfer these droplets into a well-plate. The platform is shown for the recovery of single beads and rare antibody secreting cells. ...

In the age of smart systems, artificial intelligence, and personalized devices, the need for effective methods to facilitate multifunctionality integration has become a necessity. One of the fields that boosts the efforts of multifunctionality integration ...

Droplet breakup is an important phenomenon in the field of microfluidics to generate daughter droplets. In this work, a novel breakup regime in the widely studied T-junction geometry is reported, where the pinch-off occurs laterally in the two outlet chann ...

the last years, increasing interest has been addressed on wearable devices for the continuous monitoring of biochemical profiles of patients and athletes. Among various markers, lactate represents one of the most interesting to deepen the knowledge on fati ...

Bubbles generated with lasers in liquids under confinement have been investigated for their potential use as the driving mechanism for liquid micro-jets in various microfluidic devices, such as needle-free jet injectors. Here, we report on the study of bub ...

Flexible electronics and particularly soft fibers and textiles are becoming key components in rapidly developing fields such as robotics, health and personal care, sensing, or implantable and wearable devices. Thus far however, the ability to impart soft a ...

Extracellular vesicles (EVs) are emerging as promising diagnostic and therapeutic tools for a variety of diseases. The characterization of EVs requires a series of orthogonal techniques that are overall time- and material-consuming. Here, a microfluidic de ...

Double emulsions, such as water-in-oil-in-water droplets, are important material platforms for conducting fundamental research and for technological applications. To date, well-defined double-emulsion droplets consisting of a single water core and a thin o ...

Hydrodynamic-based microfluidic platforms enable single-cell arraying and analysis over time. Despite the advantages of established microfluidic systems, long-term analysis and proliferation of cells selected in such devices require off-chip recovery of ce ...

Metal nanoparticles are frequently employed for the colorimetric detection of specific target molecules using an aggregation-induced shift of the localized surface plasmon resonance. However, metal nanoparticles dispersed in bulk solutions are prone to be ...

The invention relates to a microfluidic device for performing digital analysis of a whole blood sample. ...

Functional analysis of primary tissue-specific stem cells is hampered by their rarity. Here I developed greatly miniaturized microfluidic devices for the multiplexed, quantitative analysis of the chemotactic properties of primary, bone marrow-derived mesen ...

Functional analysis of primary tissue-specific stem cells is hampered by their rarity. Here we describe a greatly miniaturized microfluidic device for the multiplexed, quantitative analysis of the chemotactic properties of primary, bone marrow-derived mese ...

Integrated microfluidic power generation and power delivery promises to be a disruptive packaging technology with the potential to combat dark silicon. It essentially consists of integrated microchannel-based electrochemical “flow cells” in a 2D/3D multipr ...

Pressure lies at the basis of operation of most microfluidic systems, and is a determinant factor in the extent of miniaturization and in limiting the throughput and time constant of the microfluidic assays. Despite the apparent importance given to fluidic ...

We present a monolithic silicon chip comprising a matrix of 84 single photon avalanche diodes (SPADs) to detect and discriminate fluorescent beads or fluorescently labeled single cells in a polydimethyl(-siloxane) (PDMS) cartridge that is positioned on top ...

On-site drug testing using easily accessible body fluids, such as saliva, has gained a lot of importance both for road safety and forensic applications. However, saliva is a complex, inhomogeneous amalgam with many different compounds, whose concentrations ...

Here we present an electrical lysis throughput of 600 microliters per minute at high cell density (108 yeast cells per ml) with 90% efficiency, thus improving the current common throughput of one microliter per minute. We also demonstrate the extraction of ...

We present a portable microsystem to quantitatively detect cocaine in human saliva. The chip combines a simple microfluidic method for multiphase liquid-liquid extraction to transfer cocaine from IR-light absorbing saliva to an IRtransparent solvent with t ...

Optical plasmonic trapping towards biological applications in microfluidics

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Recovery of phenotypically sorted cells using droplet-digital microfluidics

Additive Fabrication of Functional Microfluidic Devices

Breaking one into three: Surface-tension-driven droplet breakup in T-junctions

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Tailored Double Emulsions Made Simple

Selective Retrieval of Individual Cells from Microfluidic Arrays Combining Dielectrophoretic Force and Directed Hydrodynamic Flow

Microfluidic Fabrication of Capsule Sensor Platform with Double-Shell Structure

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Development of microfluidic devices for chemotaxis of primary stem cells

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Micro Particle Shadow Velocimetry (µPSV) of Single- and Two-phase Flows through Microchannels

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Opportunities for high-pressure microfluidics in biomedical applications

Fluorescent magnetic bead and cell differentiation/counting using a CMOS SPAD matrix

Integrated Microfluidic Liquid-Liquid Extraction for Cocaine Detection in Human Saliva

Very High Throughput Electrical Cell Lysis and Extraction of Intracellular Compounds Using 3D Carbon Electrodes in Lab-on-a-Chip Devices

Droplet-based Liquid-Liquid Extraction and On-Chip IR-Waveguide-Spectroscopy Detection of Cocaine in Human Saliva