Publication

Droplet-based Liquid-Liquid Extraction and On-Chip IR-Waveguide-Spectroscopy Detection of Cocaine in Human Saliva

Nico de Rooij, Hans Peter Herzig, Peter Van der Wal, Alexandra Anne Labiba Kämpfer-Homsy, Lubos Hvozdara, Yu-Chi Chang, Philip Wägli
2012
Conference Papers

Abstract

We present a portable microsystem to quantitatively detect cocaine in human saliva. The chip combines a simple microfluidic method for multiphase liquid-liquid extraction to transfer cocaine from IR-light absorbing saliva to an IRtransparent solvent with the on-chip cocaine detection by IR-waveguide-spectroscopy (QC-laser, waveguide, detector). With our droplet-based extraction method we achieve an additional analyte pre-concentration of at least two orders of magnitude.

Official source

https://infoscience.epfl.ch/entities/publication/425a4e23-805f-423d-b024-1a5c92a52a2a

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Droplet-based Liquid-Liquid Extraction and On-Chip IR-Waveguide-Spectroscopy Detection of Cocaine in Human Saliva

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