Publications related to Surface enhanced nuclear magnetic resonance spectroscopy at solid-liquid interfaces using Overhauser dynamic nuclear polarization

Related publications (21)

Diffusion of brain metabolites highlights altered brain microstructure in type C hepatic encephalopathy: a 9.4 T preliminary study

Cristina Ramona Cudalbu Moldovan, Dunja Simicic, Katarzyna Pierzchala, Jessie Julie Mosso, Guillaume Miro André Briand

Introduction Type C hepatic encephalopathy (HE) is a decompensating event of chronic liver disease leading to severe motor and cognitive impairment. The progression of type C HE is associated with changes in brain metabolite concentrations measured by 1H m ...

Frontiers Media Sa2024

Bridging Native and Intrinsic Structures of Microhydrated Biomolecules by Cold Ion Spectroscopy

Andrei Zviagin

Solving native structures of such large molecules, like biomolecules, is often challenging, particularly due to the potentially infinite number of non-covalent interactions with water. In this thesis, we report the use of cold ion gas-phase action spectros ...

EPFL2023

Solid-state NMR spectroscopy

David Lyndon Emsley

Solid-state nuclear magnetic resonance (NMR) spectroscopy is an atomic-level method to determine the chemical structure, 3D structure and dynamics of solids and semi-solids. This Primer summarizes the basic principles of NMR spectroscopy as applied to the ...

SPRINGERNATURE2021

Methods to Enhance Nuclear Magnetic Resonance Sensitivity at High Magnetic Field

Claudia Christina Zanella

MR is a well-established technique routinely used in preclinical and clinical studies. This thesis focussed on the improvement of sensitivity of different methods in MR. Hyperpolarized 129Xe gas is used for studying pulmonary disease or cerebral perfusion ...

EPFL2021

Methylammonium Triiodide for Defect Engineering of High-Efficiency Perovskite Solar Cells

Viktor Skorjanc, Michael Graetzel, Shaik Mohammed Zakeeruddin, Ursula Röthlisberger, Ulf Anders Hagfeldt, Jacques-Edouard Moser, Mounir Driss Mensi, Pascal Alexander Schouwink, Felix Thomas Eickemeyer, Bowen Yang, Lukas Pfeifer, Linfeng Pan, Paramvir Ahlawat, Essa Awadh R Alharbi, Claudia Esther Avalos, Mathias Dankl, George Cameron Fish, Thomas Paul Baumeler, Anurag Krishna, Olivier Ouellette

The defects present in metal halide perovskite are deleterious to both the performance and stability of photovoltaic devices. Consequently, there is an intense focus on developing defect mitigation strategies. Herein we report a facile strategy that employ ...

2021

Sensitivity Enhancements in Lithium Titanates by Incipient Wetness Impregnation DNP NMR

David Lyndon Emsley, Pierrick Berruyer, Pinelopi Moutzouri, Michael Allan Hope, Snaedis Björgvinsdóttir

Solid-state NMR spectroscopy is a widely used method for investigating structural and electronic properties of inorganic materials, but its use is often limited by low sensitivity. Here, we show how solvent-generated dynamic nuclear polarization can be use ...

2020

Dynamic Nuclear Polarization Enhancement of 200 at 21.15 T Enabled by 65 kHz Magic Angle Spinning

David Lyndon Emsley, Gabriele Stevanato, Pierrick Berruyer, Yu Rao, Snaedis Björgvinsdóttir, Andrea Bertarello

Solid-state nuclear magnetic resonance under magic angle spinning (MAS) enhanced with dynamic nuclear polarization (DNP) is a powerful approach to characterize many important classes of materials, allowing access to previously inaccessible structural and d ...

2020

New Approaches to NMR Crystallography

Federico Maria Paruzzo

The first full protocol for nuclear magnetic resonance (NMR) crystallography (NMRX) using chemical shifts was developed a decade ago, and it combines experimental isotropic chemical shifts with crystal structure prediction (CSP) and with the calculation of ...

EPFL2019

Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies

David Lyndon Emsley, Marc Anthony Caporini

We report dynamic nuclear polarization (DNP)-enhanced magic-angle spinning (MAS) NMR spectroscopy in viral capsids from HIV-1 and bacteriophage AP205. Viruses regulate their life cycles and infectivity through modulation of their structures and dynamics. W ...

2019

Structure of Lipid Nanoparticles Containing siRNA or mRNA by Dynamic Nuclear Polarization-Enhanced NMR Spectroscopy

David Lyndon Emsley, Aaron James Rossini, Arthur César Pinon, Jasmine Viger-Gravel

Here, we show how dynamic nuclear polarization (DNP) NMR spectroscopy experiments permit the atomic level structural characterization of loaded and empty lipid nanoparticles (LNPs). The LNPs used here were synthesized by the microfluidic mixing technique a ...

2018

Transportable hyperpolarized metabolites

Geoffrey Bodenhausen, David Lyndon Emsley, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud, Aaron James Rossini, Xiao Ji

Nuclear spin hyperpolarization of C-13-labelled metabolites by dissolution dynamic nuclear polarization can enhance the NMR signals of metabolites by several orders of magnitude, which has enabled in vivo metabolic imaging by MRI. However, because of the s ...

Nature Publishing Group2017

Quantum critical scaling for a Heisenberg spin-1/2 chain around saturation

Mingee Chung, Henrik Moodysson Rønnow

We demonstrate quantum critical scaling for an S = 1/2 Heisenberg antiferromagnetic chain compound Cu(C4H4N2)(NO3)(2) in a magnetic field around saturation, by analyzing previously reported magnetization [Y. Kono et al., Phys. Rev. Lett. 114, 037202 (2015) ...

American Physical Society2015

Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides

Christian Heinis, Florence Pojer, Rudolf Hovius, Shiyu Chen, Ranganath Gopalakrishnan

The disulfide bonds that form between two cysteine residues are important in defining and rigidifying the structures of proteins and peptides. In polypeptides containing multiple cysteine residues, disulfide isomerization can lead to multiple products with ...

Nature Publishing Group2014

Fourier tickling for homonuclear decoupling in nmr

Geoffrey Bodenhausen, Diego Carnevale

PROBLEM TO BE SOLVED: To provide an effective and speedy method for decoupling of homonuclear couplings.SOLUTION: This invention concerns a method for high resolution NMR (nuclear magnetic resonance) measurements comprising the application of excitation pu ...

2013

Biphasic water splitting by osmocene

Hubert Girault, Xile Hu, Anne-Clémence Corminboeuf, Heron Vrubel, Manuel Alejandro Méndez Agudelo, Astrid Johana Olaya Avendano, Peiyu Ge, Imren Hatay, Tanya Kumanova Yordanova

The photochemical reactivity of osmocene in a biphasic water-organic solvent system has been investigated to probe its water splitting properties. The photoreduction of aqueous protons to hydrogen under anaerobic conditions induced by osmocene dissolved in ...

National Academy of Sciences2012

Long lived states in high field NMR spectroscopy for the study of very slow dynamic processes in solution state

Riddhiman Sarkar

In solution-state NMR spectroscopy, dynamic processes can be probed provided the nuclear relaxation rate constant does not exceed the rate constant of the process. Phenomena occurring on a time scale longer than the spin-lattice relaxation time constant, T ...

EPFL2009

Measurement of Slow Diffusion Coefficients of Molecules with Arbitrary Scalar Couplings via Long-Lived Spin States

Geoffrey Bodenhausen, Riddhiman Sarkar, Paul Romeo Vasos, Puneet Ahuja

New experiments are described for the determination of very slow diffusion constants by nuclear magnetic resonance (NMR) using long-lived (singlet) states. These experiments are suitable for molecules or conformations featuring a wide range of J-couplings. ...

2008

Exchange Rate Constants of Invisible Protons in Proteins Determined by NMR Spectroscopy

Geoffrey Bodenhausen

Although labile protons that are exchanging rapidly with those of the solvent cannot be observed directly, their exchange rate constants can be determined by indirect detection of scalar-coupled neighboring nuclei. We have used heteronuclear NMR spectrosco ...

2008

Electron spin resonance of single-walled carbon nanotubes and related structures

László Forró, Bálint Náfrádi

We report new results on the electron spin resonance of single walled carbon nanotubes, peapods and double walled carbon nanotubes. A small ESR line is present in well purified samples and its temperature dependence reveals a striking 'super-Curie' paramag ...

2006

Temperature-dependent protein backbone dynamics from auto- and cross-correlated NMR relaxation rates

Geoffrey Bodenhausen

The temp. dependence of NMR relaxation rates was investigated for the backbone of 15N/13C labeled human ubiquitin in the temp. range of 20-50 DegC. The 15N autorelaxation rates give evidence that the potential energy functions for 15N-HN bonds are not quad ...

Springer, Springer-Verlag2005