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Philippe Renaud

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Related publications (301)

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Instrumented Knee Prosthesis for Force and Kinematics Measurements

Steve Tanner, Kamiar Aminian, Philippe Renaud, Catherine Dehollain, Arnaud Bertsch, Peter Ryser, Eric Meurville, Pierre-André Farine, Oguz Atasoy, Brigitte Jolles-Haeberli, Arash Arami, Willyan Hasenkamp Carreira, Shafqat Ali, Matteo Simoncini

In this work, we present the general concept of an instrumented smart knee prosthesis for in-vivo measurement of forces and kinematics. This system can be used for early monitoring of the patient after implantation and prevent possible damage to the prosth ...

Ieee-Inst Electrical Electronics Engineers Inc2013

Simulation of epiretinal prostheses - Evaluation of geometrical factors affecting stimulation thresholds

Philippe Renaud, Grégoire Cosendai, Arnaud Bertsch, Sri Harsha Kasi Raj, Willyan Hasenkamp Carreira

Background An accurate understanding of the electrical interaction between retinal prostheses and retinal tissue is important to design effective devices. Previous studies have used modelling approaches to simulate electric fields generated by epiretinal p ...

BioMed Central2011

Facile fabrication of nanofluidic diode membranes using anodic aluminium oxide

Philippe Renaud, Arnaud Bertsch, Jürgen Brugger, Fabien Patrick Wildhaber, Oscar Vazquez Mena, Songmei Wu

Active control of ion transport plays important roles in chemical and biological analytical processes. Nanofluidic systems hold the promise for such control through electrostatic interaction between ions and channel surfaces. Most existing experiments rely ...

Royal Soc Chemistry2012

Link between Alginate Reaction Front Propagation and General Reaction Diffusion Theory

Philippe Renaud, Jürgen Brugger, Thomas Michael Braschler, Kristopher Pataky, Ana Valero, Ludovica Colella

We provide a common theoretical framework reuniting specific models for the Ca2+-alginate system and general reaction diffusion theory along with experimental validation on a microfluidic chip. As a starting point, we use a set of nonlinear, partial differ ...

2011

First steps towards interlocking modular microfluidic cooling substrates (i-MμCS) for future silicon tracking detectors in High Energy Physics (HEP)

Philippe Renaud, Massimo Angeletti

In future High Energy Physics detectors, the coverage of large surfaces with silicon pixel chip sensors poses a challenge for the sensors positioning, for their cooling, assembly, and interconnection. The use of a cooling substrate on which the sensors are ...

2022

Bi-directional AC electrothermal micropump for on-chip biological applications

Philippe Renaud, Harald Van Lintel, Jürgen Brugger

The ability to control and pump high ionic strength fluids inside microchannels forms a major advantage for clinical diagnostics and drug screening processes, where high conductive biological and physiological buffers are used. Despite the known potential ...

Wiley-Blackwell2016

Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS

Patrick Aebischer, Philippe Renaud, Sylvain Eric Lengacher, Pierre Magistretti, Anja Kunze, Elisabeth Anne Dirren

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. ALS is believed to be a non-cell autonomous condition, as other cell types, including astrocytes, have been implicated in disease pathogenesis. Hence, to facilitate the developmen ...

Royal Soc Chemistry2013

On-chip extrusion of lipid vesicles and tubes through microsized apertures

Philippe Renaud

In this work we present the formation of micrometre-sized lipid vesicles and tubes with perfectly homogeneous diameter and extraordinary length. The method is a novel approach for unconventional fabrication of soft-matter microstructured devices based on t ...

2006

Effect of the surface charge on ion transport through nanoslits

Philippe Renaud, Harald Van Lintel, Reto Bruno Schoch

A description of ion transport through geometrically defined nanoslits is presented. It is characterized by the effective surface charge density and was obtained by impedance spectroscopy measurements of electrolytes with different physico-chemical propert ...

2005

Al2O3/W hetero-structured nanopore membranes: From native to tunable nanofluidic diodes

Philippe Renaud, Arnaud Bertsch, Jürgen Brugger, Fabien Patrick Wildhaber, Songmei Wu

We present here Al2O3/W hetero-structured nanopore membranes which function as native and electrical field tunable nanofluidic diodes. A typical membrane is 100×100 μm2 in size with pore density of ∼ 20/μm2. The nanopores are 26 nm in diameter and 400 nm i ...

IEEE2013

Gentle cell trapping and release on a microfluidic chip by in situ alginate hydrogel formation

Philippe Renaud, Lynda Metref, Thomas Michael Braschler

Microfluidic devices are increasingly used to perform biological experiments on a single-cell basis. However, long-term stability of cell positions is still an issue. A novel biocompatible method for cell entrapment and release on a microchip is presented. ...

2005

Devices, systems and methods for dispensing and analysing particles

Philippe Renaud, Yann Barrandon, David Vincent Bonzon, Jean-Baptiste Bureau

The present invention relates to a pipette tip comprising a thin holed membrane at its distal end, which is designed to be adapted with a system comprising at least an impedance analyser and a fluidic actuator to perform the dispensing and analysis of part ...

2016

MyDEP: A New Computational Tool For Dielectric Modeling Of Particles And Cells

Philippe Renaud, Jonathan Bastien Cottet

Before performing experiments in the lab with dielectrophoresis (DEP), it is useful to predict the particle and cell responses to the electric field. This requires knowledge of particles or cells properties, which can be obtained from the literature, and i ...

2018

Modelling and microfabrication of a polyimide-based 3D tissue coupled electrodes for electrical stimulation in the chick retina

Philippe Renaud, Sri Harsha Kasi Raj

We present a new flexible microfabricated polyimide-based platinum array of 3D “tissue coupled electrodes” (TCEs) applied for local stimulation of the chick retinal photoreceptor layer and simultaneous patch clamp recording from a single retinal ganglion c ...

2008

A Three-Dimensional Engineered Cardiac In Vitro Model: Controlled Alignment of Cardiomyocytes in 3D Microphysiological Systems

Philippe Renaud, Fatemeh Navaee

Cardiomyocyte alignment in myocardium tissue plays a significant role in the physiological, electrical, and mechanical functions of the myocardium. It remains, however, difficult to align cardiac cells in a 3D in vitro heart model. This paper proposes a si ...

MDPI2023

Fabrication of thermo-responsive nano-valve by grafting-to in melt of poly(N-isopropylacrylamide) onto nanoporous silicon nitride membranes

Philippe Renaud, Alexandre Zenon Ivan Bojko

This article reports the grafting-to in melt of amino and carboxy-terminated poly(N-isopropylacrylamide) (PNIPAM) onto ultrathin nanoporous silicon nitride membranes (NSiNMs) with a mean pore size of 85 +/- 15 nm functionalized respectively with a self-ass ...

Elsevier2014

Separation of platelets from other blood cells in continuous-flow by dielectrophoresis field-flow-fractionation

Philippe Renaud, Niccolo Piacentini

We present a microfluidic device capable of separating platelets from other blood cells in continuous flow using dielectrophoresis field-flow-fractionation. The use of hydrodynamic focusing in combination with the application of a dielectrophoretic force a ...

American Institute of Physics2011

High precision, high throughput generation of droplets containing single cells

Philippe Renaud, Arnaud Bertsch, Jiande Zhou

The Poisson limit is a major problem for the isolation of single cells in different single-cell technologies and applications. In droplet-based single-cell assays, a scheme that is increasingly popular, the intrinsic randomness during single-cell encapsula ...

ROYAL SOC CHEMISTRY2022

A Compressible Scaffold for Minimally Invasive Delivery of Large Intact Neuronal Networks

Philippe Renaud, Thomas Michael Braschler, Patrick Fraering, Oliver Peric, Georg Fantner, Sébastien Mosser, Amélie Barbara Hildegarde Béduer

Millimeter to centimeter-sized injectable neural scaffolds based on macroporous cryogels are presented. The polymer-scaffolds are made from alginate and carboxymethyl-cellulose by a novel simple one-pot cryosynthesis. They allow surgical sterility by means ...

Wiley-VCH Verlag2015

Temperature Sensitivity of Nanochannel Electrical Conductance

Philippe Renaud, Arnaud Bertsch, Mojtaba Taghipoor

Electrical measurement is a widely used technique for the characterization of nanofluidic devices. The electrical conductivity of electrolytes is known to be dependent on temperature. However, the similarity of the temperature sensitivity of the electrical ...

Amer Chemical Soc2015