Publications by Matthias Lütolf

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The invention provides a method for obtaining a three-dimensional (3D) cellular model of tissue fibrosis, such as liver fibrosis, comprising culturing epithelial cells in a 3D hydrogel in conditions suitable for a three-dimensional cellular cluster formati ...

The invention relates to methods for developing and maintaining organoids and the organoids produced thereby. ...

The present disclosure relates to a microfluidic device comprising: a substrate; a culture chamber (130); a loading channel (170) in fluid communication with the culture chamber; at least one auxiliar channel (170-1, 5 170-2) extending from and in fluid co ...

The invention relates to a scaffold material comprising a carrier and embedded microbeads for use in tissue engineering applications such as soft tissues therapeutic treatment. The scaffold provides a short-term bulking effect coupled with a long-term func ...

A composition comprising a first material and a second material, wherein said first material is cross-linkable by a first cross- linking reaction and said second material is cross-linkable by a second cross-linking reaction, wherein said first cross-linkin ...

In this Tools of the Trade article, Francisco Lorenzo-Mart & iacute;n and Matthias Lutolf present mini-colons as a new ex vivo cancer model that incorporates microfabrication, tissue engineering and optogenetics. ...

The present invention relates to dual fluorophore ratiometric mitochondrial pH probes, their uses and their manufacture. ...

Polarised three-dimensional cellular aggregates (or gastruloids) generated in vitro from one or more pluripotent stem cells are provided. Methods for obtaining polarised three-dimensional cellular aggregates and cells (e.g. progenitor cells and derivatives ...

Matthias Lütolf

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Matthias Lutolf, interviewed by Peter Loskill (Vice-Chair of EUROoC, the European-Organ-on-Chip-Society)

Three dimensional models of tissue fibrosis

High-Throughput Screening Of Stem Cell Microenvironments

Device for manipulating mammalian cells with high collection capability

The NAD plus Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division

Breaking the Barriers in Engineering Organoids and Tissues with Advanced Materials

Organoid tissue engineering

Microfluidic devices

Natural polymer-derived scaffold material and methods for production thereof

A method for building a structure containing living cells

Mini-colons unlock tumour development outside the body

Keynote: Deconstructing and reconstructing stem cell niches

Instructing stem cell fate by engineered niches

Artificial extracellular matrices for bone tissue engineering

Stem cell-materials interactions

Mitochondrial ph probe

Mitochondrial Activity Determines Hematopoietic Stem Cell Fate Decisions

Polarised three-dimensional cellular aggregates

3D growth factor patterned cell substrates to locally control cellular behavior

In Vivo Modulation of Mitochondrial Activity Determines HSC Engraftment and Post-Transplant Survival in Mice