Publication

Three dimensional models of tissue fibrosis

Matthias Lütolf, Saba Rezakhani, Giovanni Sorrentino, Ece Yildiz
2020
Patents

Abstract

The invention provides a method for obtaining a three-dimensional (3D) cellular model of tissue fibrosis, such as liver fibrosis, comprising culturing epithelial cells in a 3D hydrogel in conditions suitable for a three-dimensional cellular cluster formation, wherein the hydrogel comprises a crosslinked hydrophilic polymer having a shear modulus of at least 4 kPa, such as between about 4 and about 10 kPa.

Official source

https://infoscience.epfl.ch/entities/publication/edd819ea-de99-4917-b86b-de142ce8fa7a

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Three dimensional models of tissue fibrosis

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