Sandra Eloise Kjeldsen

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Publications associées (27)

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DUX is a non-essential synchronizer of zygotic genome activation

Didier Trono, Sandra Eloise Kjeldsen, Delphine Yvette L Grun, Sonia Verp, Alberto De Iaco

Some of the earliest transcripts produced in fertilized human and mouse oocytes code for DUX, a double homeodomain protein that promotes embryonic genome activation (EGA). Deleting Dux by genome editing at the 1- to 2-cell stage in the mouse impairs EGA an ...

2019

Pou5f1b inhibitors

Didier Trono, Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Sandra Eloise Kjeldsen, Laia Simo Riudalbas

The invention provides an agent modulating the expression and/or activity of i) the POU5F1B protein, a fragment or variant thereof, ii) an mRNA encoding POU5F1B, a fragment or variant thereof and/or iii) the POU5F1B gene. Preferably, the agent is for use i ...

2024

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

Didier Trono, Laurence Gouzi Abrami, Julien Léonard Duc, Sandra Eloise Kjeldsen, Evaristo Jose Planet Letschert, Alexandre Coudray, Laia Simo Riudalbas, Sagane Dind

AMER ASSOC CANCER RESEARCH2021

A KRAB/KAP1-miRNA Cascade Regulates Erythropoiesis Through Stage-Specific Control of Mitophagy

Didier Trono, Jiri Vanicek, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Isabelle Barde, Andrea Corsinotti, Ray Marcel Marin Florez, Benjamin Rauwel, Sonia Verp

During hematopoiesis, lineage- and stage-specific transcription factors work in concert with chromatin modifiers to direct the differentiation of all blood cells. Here, we explored the role of KRAB-containing zinc finger proteins (KRAB-ZFPs) and their cofa ...

American Association for the Advancement of Science2013

Control of mitophagie by microRNAs - A key step of erythropoiesis

Didier Trono, Jiri Vanicek, Sandra Eloise Kjeldsen, Sonia Verp, Adamantia Kapopoulou, Isabelle Barde, Ray Marcel Marin Florez, Benjamin Rauwel, Andrea Corsinotti

Edp Sciences S A2014

Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma

Didier Trono, Kai Johnsson, Sandra Eloise Kjeldsen, Nadine Fournier, Adamantia Kapopoulou, Marco Cassano, Karolina Bojkowska

Wiley-Blackwell2012

Potential Of Induced Pluripotent Stem Cells For The Treatment Of Crigler-Najjar Liver Disease

Didier Trono, Sandra Eloise Kjeldsen, Marc Samuel Friedli

Elsevier Science Bv2015