Sandra Eloise Kjeldsen

About
Privacy
Disclaimer

Graph Chatbot

Related publications (29)

A KRAB/KAP1-miRNA Cascade Regulates Erythropoiesis Through Stage-Specific Control of Mitophagy

Didier Trono, Isabelle Barde, Sonia Verp, Andrea Corsinotti, Jiri Vanicek, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Ray Marcel Marin Florez, Benjamin Rauwel

During hematopoiesis, lineage- and stage-specific transcription factors work in concert with chromatin modifiers to direct the differentiation of all blood cells. Here, we explored the role of KRAB-containing zinc finger proteins (KRAB-ZFPs) and their cofa ...

American Association for the Advancement of Science2013

Efficient sperm cryopreservation and recovery of mouse lines from various backgrounds

Isabelle Barde, Sonia Verp, Sandra Eloise Kjeldsen, Xavier Warot, Michelle Blom

Springer2013

The KRAB-ZFP/KAP1 System Contributes to the Early Embryonic Establishment of Site-Specific DNA Methylation Patterns Maintained during Development

Didier Trono, Priscilla Turelli, Karolina Bojkowska, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Charlène Mireille Raymonde Raclot

De novo DNA methylation is an essential aspect of the epigenetic reprogramming that takes place during early development, yet factors responsible for its instatement at particular genomic loci are poorly defined. Here, we demonstrate that the KRAB-ZFP-medi ...

Elsevier2012

Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma

Kai Johnsson, Didier Trono, Karolina Bojkowska, Francesca Santoni de Sio, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Nadine Fournier, Cristina Cartoni, Marco Cassano, Fabio Aloisio

Wiley-Blackwell2012

Measuring In Vivo Protein Half-Life

Kai Johnsson, Christian Heinis, Didier Trono, Isabelle Barde, Sonia Verp, Karolina Bojkowska, Francesca Santoni de Sio, Sandra Eloise Kjeldsen

Protein turnover critically influences many biological functions, yet methods have been lacking to assess this parameter in vivo. Here, we demonstrate how chemical labeling of SNAP-tag fusion proteins can be exploited to measure the half-life of resident i ...

Elsevier2011

IFN alpha activates dormant haematopoietic stem cells in vivo

Sandra Eloise Kjeldsen

Maintenance of the blood system is dependent on dormant haematopoietic stem cells (HSCs) with long-term self-renewal capacity. After injury these cells are induced to proliferate to quickly reestablish homeostasis(1). The signalling molecules promoting the ...

2009

c-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia

Armin Ehninger, Christelle Dubey, Sandra Eloise Kjeldsen

In the adult liver, 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene (TCPOBOP), an agonist of the constitutive androstane receptor (CAR, NR1I3), produces rapid hepatomegaly in the absence of injury. In this study, we identify c-Myc as a gene induced by CAR and ...

2008

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

Cyrille Dunant, Maike Jaworski, Sandra Eloise Kjeldsen, Anne Wilson

Bone marrow hematopoietic stem cells (HSCs) are crucial to maintain lifelong production of all blood cells. Although HSCs divide infrequently, it is thought that the entire HSC pool turns over every few weeks, suggesting that HSCs regularly enter and exit ...

2008

IFN-alpha PROMOTES PROLIFERATION OF DORMANT HSCS IN VIVO, MAKING THEM SUSCEPTIBLE TO ELIMINATION BY CHEMOTHERAPY

Sandra Eloise Kjeldsen

2008

Page 2 of 2