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Tobias Kober

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Publications associées (151)

Older patients with multiple sclerosis have greater enlargement of the brain ventricles following COVID-19

Bénédicte Marie Maréchal, Tobias Kober

SAGE PUBLICATIONS LTD2022

Variability and reproducibility of multi-echo T2 relaxometry: Insights from multi-site, multi-session and multi-subject MRI acquisitions

Jean-Philippe Thiran, Tobias Kober, Elda Fischi Gomez, Alessandro Daducci, Tom Hilbert, Elena Beanato, Gabriel Girard, Julia Brügger, Gian Franco Piredda, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Erick Jorge Canales Rodriguez, Marco Pizzolato, Andéol Geoffroy Cadic-Melchior, Thomas Yu, Chang-Hyun Park

Quantitative magnetic resonance imaging (qMRI) can increase the specificity and sensitivity of conventional weighted MRI to underlying pathology by comparing meaningful physical or chemical parameters, measured in physical units, with normative values acqu ...

2022

Real-time shimming with FID navigators

Tobias Kober

Purpose: To implement a method for real-time field control using rapid FID navigator (FIDnav) measurements and evaluate the efficacy of the proposed approach for mitigating dynamic field perturbations and improving T-2*-weighted image quality. ...

WILEY2022

Neuroimaging Harmonization Using cGANs: Image Similarity Metrics Poorly Predict Cross-Protocol Volumetric Consistency

Jean-Philippe Thiran, Bénédicte Marie Maréchal, Tobias Kober, Veronica Lily Ravano

Computer-aided clinical decision support tools for radiology often suffer from poor generalizability in multi-centric frameworks due to data heterogeneity. In particular, magnetic resonance images depend on a large number of acquisition protocol parameters ...

Springer International Publishing Ag2022

Prospective motion correction in kidney MRI using FID navigators

Tobias Kober

Purpose Abdominal MRI scans may require breath-holding to prevent image quality degradation, which can be challenging for patients, especially children. In this study, we evaluate whether FID navigators can be used to measure and correct for motion prospec ...

WILEY2022

Submillimeter T-1 atlas for subject-specific abnormality detection at 7T

Jean-Philippe Thiran, Bénédicte Marie Maréchal, Tobias Kober, Tom Hilbert, Ricardo Alberto Corredor Jerez, Gian Franco Piredda

Purpose: Studies at 3T have shown that T-1 relaxometry enables characterization of brain tissues at the single-subject level by comparing individual physical properties to a normative atlas. In this work, an atlas of normative T-1 values at 7T is introduce ...

WILEY2022

Compressed sensing (CS) MP2RAGE versus standard MPRAGE: A of derived brain volume measurements

Tobias Kober, Tom Hilbert, Gian Franco Piredda

Purpose: T1 Magnetization Prepared Two Rapid Acquisition Gradient Echo (MP2RAGE) with compress sensing (CS) has been proposed as an improvement of the standard MPRAGE sequence with multiple advantages including reduced acquisition time needed to provide a ...

ELSEVIER SCI LTD2022

Comparison of non-parametric T2 relaxometry methods for myelin water quantification

Jean-Philippe Thiran, Nicolas Kunz, Tobias Kober, Alessandro Daducci, Tom Hilbert, Gian Franco Piredda, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Multi-component T2 relaxometry allows probing tissue microstructure by assessing compartment-specific T2 relaxation times and water fractions, including the myelin water fraction. Non-negative least squares (NNLS) with zero-order Tikhonov regularization is ...

2021

Toward fully automated assessment of the central vein sign using deep learning

Tobias Kober, Mario Joao Fartaria de Oliveira

SAGE PUBLICATIONS LTD2021

T-1-Based Synthetic Magnetic Resonance Contrasts Improve Multiple Sclerosis and Focal Epilepsy Imaging at 7 T

Tobias Kober

Objectives ...

LIPPINCOTT WILLIAMS & WILKINS2021

Leman-PV as a clinical decision-support tool to assess MS activity: a multicentric longitudinal study at 1.5T and 3T MRI

Bénédicte Marie Maréchal, Tobias Kober, Ricardo Alberto Corredor Jerez

SAGE PUBLICATIONS LTD2021

Clinical correlates of white matter lesions in Parkinson's disease using automated multi-modal segmentation measures

Bénédicte Marie Maréchal, Tobias Kober

Background: Age-related white matter lesions (WML) are common, impact neuronal connectivity, and affect motor function and cognition. In addition to pathological nigrostriatal losses, WML are also common co morbidities in Parkinson's disease (PD) that affe ...

ELSEVIER2021

Comparison of 2D simultaneous multi-slice and 3D GRASE readout schemes for pseudo-continuous arterial spin labeling of cerebral perfusion at 3 T

Bénédicte Marie Maréchal, Tobias Kober, Tom Hilbert

Objective In this perfusion magnetic resonance imaging study, the performances of different pseudo-continuous arterial spin labeling (PCASL) sequences were compared: two-dimensional (2D) single-shot readout with simultaneous multislice (SMS), 2D single-sho ...

SPRINGER2021

Revisiting the T-2 spectrum imaging inverse problem: Bayesian regularized non-negative least squares

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Multi-echo T-2 magnetic resonance images contain information about the distribution of T-2 relaxation times of compartmentalized water, from which we can estimate relevant brain tissue properties such as the myelin water fraction (MWF). Regularized non-neg ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2021

Data-driven myelin water imaging based on T-1 and T-2 relaxometry

Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato

Long acquisition times preclude the application of multiecho spin echo (MESE) sequences for myelin water fraction (MWF) mapping in daily clinical practice. In search of alternative methods, previous studies of interest explored the biophysical modeling of ...

WILEY2021

Improving diagnosis accuracy of brain volume abnormalities during childhood with an automated MP2RAGE-based MRI brain segmentation

Bénédicte Marie Maréchal, Tobias Kober

Background and purpose. - It can be challenging to depict brain volume abnormalities in the pediatric population on magnetic resonance imaging (MRI). The aim of the study was to evaluate the inter-radiologist reliability in brain MRI interpretation, includ ...

MASSON EDITEUR2021

Simulated Half-Fourier Acquisitions Single-shot Turbo Spin Echo (HASTE) of the Fetal Brain: Application to Super-Resolution Reconstruction

Meritxell Bach Cuadra, Patric Hagmann, Reto Meuli, Sébastien Tourbier, Tobias Kober, Hamza Kebiri, Tom Hilbert, Thomas Yu

Accurate characterization of in utero human brain maturation is critical as it involves complex interconnected structural and functional processes that may influence health later in life. Magnetic resonance imaging is a powerful tool complementary to the u ...

SPRINGER INTERNATIONAL PUBLISHING AG2021

Normal volumetric and T1 relaxation time values at 1.5 T in segmented pediatric brain MRI using a MP2RAGE acquisition

Jean-Philippe Thiran, Bénédicte Marie Maréchal, Tobias Kober, Tom Hilbert, Gian Franco Piredda

Objectives This study introduced a tailored MP2RAGE-based brain acquisition for a comprehensive assessment of the normal maturing brain. Methods Seventy normal patients (35 girls and 35 boys) from 1 to 16 years of age were recruited within a prospective mo ...

SPRINGER2021

Clinical implementation of accelerated T-2 mapping: Quantitative magnetic resonance imaging as a biomarker for annular tear and lumbar disc herniation

Tobias Kober, Tom Hilbert, Michael Weber

Objectives This study evaluates GRAPPATINI, an accelerated T-2 mapping sequence combining undersampling and model-based reconstruction to facilitate the clinical implementation of T-2 mapping of the lumbar intervertebral disc. Methods Fifty-eight individua ...

SPRINGER2021

Validating atlas-based lesion disconnectomics in multiple sclerosis: A retrospective multi-centric study

Jonas Richiardi, Reto Meuli, Bénédicte Marie Maréchal, Tobias Kober, Mario Joao Fartaria de Oliveira

The translational potential of MR-based connectivity modelling is limited by the need for advanced diffusion imaging, which is not part of clinical protocols for many diseases. In addition, where diffusion data is available, brain connectivity analyses rel ...

2021

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