Publications de Tobias Kober | EPFL Graph Search

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Objectives: To evaluate the diagnostic usefulness of synthetic T2-weighted images of the lumbar spine derived from ten-fold undersampled k-space data using GRAPPATINI, a combination of a model-based approach for rapid T2 and M0 quantification (MARTINI) ext ...

Background Early infratentorial and focal spinal cord lesions on magnetic resonance imaging (MRI) are associated with a higher risk of long-term disability in patients with multiple sclerosis (MS). The role of diffuse spinal cord lesions remains less under ...

Purpose To suppress the noise, by sacrificing some of the signal homogeneity for numerical stability, in uniform T1 weighted (T1w) images obtained with the magnetization prepared 2 rapid gradient echoes sequence (MP2RAGE) and to compare the clinical utilit ...

Background: Basal ganglia lesions are typical findings on magnetic resonance imaging (MRI) of the brain in survivors of acute methanol poisoning. However, no data are available on the association between the magnitude of damaged brain regions, serum concen ...

Objective To investigate the utility of an automatic deep learning (DL) method for segmentation of T2 maps in patients with idiopathic inflammatory myopathy (IIM) against healthy controls, and also the association of quantitative T2 values in patients with ...

Objectives: The aim of this study was to study focal cerebellar pathology in early stages of multiple sclerosis (MS) using ultra-high-field magnetization-prepared 2 inversion-contrast rapid gradient-echo (7T MP2RAGE). Materials and Methods: Twenty early-st ...

Purpose: To develop a self-navigated motion compensation strategy for 3D radial MRI that can compensate for continuous head motion by measuring rigid body motion parameters with high temporal resolution from the central k-space acquisition point (self-enco ...

Objectives: Lesion detection and characterization in multiple sclerosis (MS) are an essential part of its clinical diagnosis and an important research field. In this pilot study, we applied the recently introduced two inversion-contrast magnetization-prepa ...

Background Long acquisition times and motion sensitivity limit T-2 mapping in the abdomen. Accelerated mapping at 3 T may allow for quantitative assessment of diffuse pancreatic disease in patients during free-breathing. Purpose To test the feasibility of ...

Objectives T(2)mapping of the intervertebral disc (IVD) can depict quantitative changes reflecting biochemical change due to loss of glycosaminoglycan content. Conventional T(2)mapping is usually performed using a 2-dimensional multi-echo-spin echo sequenc ...

Objectives Fluid and white matter suppression (FLAWS) is a recently proposed magnetic resonance sequence derived from magnetization-prepared 2 rapid acquisition gradient-echo providing 2 coregistered datasets with white matter- and cerebrospinal fluid-supp ...

BACKGROUND AND PURPOSE: MS lesions exhibit varying degrees of axonal and myelin damage. A comprehensive description of lesion phenotypes could contribute to an improved radiologic evaluation of smoldering inflammation and remyelination processes. This stud ...

Functional magnetic resonance imaging (fMRI) measures activation-induced signal changes by means of the blood-oxygenation-level-depended (BOLD) contrast. Since signal changes are typically only 1-3%, the method is intrinsically sensitive to all signal inst ...

Objectives This study introduced a tailored MP2RAGE-based brain acquisition for a comprehensive assessment of the normal maturing brain. Methods Seventy normal patients (35 girls and 35 boys) from 1 to 16 years of age were recruited within a prospective mo ...

Purpose: Delineation of subtle lesions in magnetic resonance imaging (MRI)-negative patients is of great importance in preoperative epilepsy evaluation. The aim of our study was to explore the diagnostic value of the novel fluid and white matter suppressio ...

BACKGROUND AND PURPOSE Changes in the brain composition of anorexics could potentially be expected, opening the door to new imaging approaches where quantitative and qualitative MRI have a role. Our purpose was to investigate anorexia-related brain dehydra ...

Three-dimensional segmented echo planar imaging (3D-EPI) is a promising approach for high-resolution functional magnetic resonance imaging, as it provides an increased signal-to-noise ratio (SNR) at similar temporal resolution to traditional multislice 2D- ...

Objectives This study evaluates GRAPPATINI, an accelerated T-2 mapping sequence combining undersampling and model-based reconstruction to facilitate the clinical implementation of T-2 mapping of the lumbar intervertebral disc. Methods Fifty-eight individua ...

We proposed a method for segmentation of brain tissues-gray matter, white matter, and cerebrospinal fluid-using multi-contrast images, including a T1 map and a uniform T1-weighted image, from a magnetization-prepared 2 rapid acquisition gradient echoes (MP ...

Objectives: Nonenhanced T1-w sequences such as magnetization-prepared 2 rapid acquisition gradient echo (MP2RAGE) and derived fluid and white matter suppression (FLAWS) have demonstrated high performance for detecting brain parenchymal and cervical spine d ...

Tobias Kober

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Synthetic T-2-weighted images of the lumbar spine derived from an accelerated T-2 mapping sequence: Comparison to conventional T(2)w turbo spin echo

Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis

Robust T1-Weighted Structural Brain Imaging and Morphometry at 7T Using MP2RAGE

MRI-based brain volumetry and retinal optical coherence tomography as the biomarkers of outcome in acute methanol poisoning

Assessment of idiopathic inflammatory myopathy using a deep learning method for muscle T2 mapping segmentation

An Ultra-High Field Study of Cerebellar Pathology in Early Relapsing-Remitting Multiple Sclerosis Using MP2RAGE

Rapid motion estimation and correction using self-encoded FID navigators in 3D radial MRI

MP2RAGE multiple sclerosis magnetic resonance imaging at 3 T

Patient respiratory-triggered quantitative T-2 mapping in the pancreas

Accelerated T(2)Mapping of the Lumbar Intervertebral Disc Highly Undersampled K-Space Data for Robust T(2)Relaxation Time Measurement in Clinically Feasible Acquisition Times

3-Dimensional Fluid and White Matter Suppression Magnetic Resonance Imaging Sequence Accelerated With Compressed Sensing Improves Multiple Sclerosis Cervical Spinal Cord Lesion Detection Compared With Standard 2-Dimensional Imaging

Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes

Adaptive FID-navigators for respiration monitoring in multi-slice fMRI applications

Normal volumetric and T1 relaxation time values at 1.5 T in segmented pediatric brain MRI using a MP2RAGE acquisition

Fluid and White Matter Suppression Imaging and Voxel-Based Morphometric Analysis in Conventional Magnetic Resonance Imaging-Negative Epilepsy

Cerebral Gray and White Matter Involvement in Anorexia Nervosa Evaluated by T1, T2, and T2*Mapping

Temporal SNR characteristics in segmented 3D-EPI at 7T

Clinical implementation of accelerated T-2 mapping: Quantitative magnetic resonance imaging as a biomarker for annular tear and lumbar disc herniation

Brain tissue segmentation based on MP2RAGE multi-contrast images in 7 T MRI

Improved MR Detection of Optic Nerve Demyelination With MP2RAGE-FLAWS Compared With T2-Weighted Fat-Saturated Sequences