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Alessandra Griffa

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Publications associées (82)

Functional connectivity underlying cognitive and psychiatric symptoms in post-COVID-19 syndrome: is anosognosia a key determinant?

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Lack of awareness of cognitive impairment (i.e. anosognosia) could be a key factor for distinguishing between neuropsychological postCOVID-19 condition phenotypes. In this context, the 2-fold aim of the present study was to (i) establish the prevalence of ...

2022

CSF tap test in idiopathic normal pressure hydrocephalus: still a necessary prognostic test?

Dimitri Nestor Alice Van De Ville, Alessandra Griffa, Maria Giulia Preti

Objective To assess whether gait, neuropsychological, and multimodal MRI parameters predict short-term symptom reversal after cerebrospinal fluid (CSF) tap test in idiopathic normal pressure hydrocephalus (iNPH). Methods Thirty patients (79.3 +/- 5.9 years ...

SPRINGER HEIDELBERG2022

Connectome Mapper 3: A Flexible and Open-Source Pipeline Software for Multiscale Multimodal Human Connectome Mapping

Meritxell Bach Cuadra, Patric Hagmann, Sébastien Tourbier, Alessandra Griffa, Emeline Mullier, Joan Rue Queralt, Mustafa Anil Tuncel, Mikkel Schöttner

2022

A multi-scale probabilistic atlas of the human connectome

Meritxell Bach Cuadra, Patric Hagmann, Elena Najdenovska, Alessandra Griffa, Maxime Descoteaux

The human brain is a complex system that can be efficiently represented as a network of structural connectivity. Many imaging studies would benefit from such network information, which is not always available. In this work, we present a whole-brain multi-s ...

NATURE PORTFOLIO2022

Brain structure-function coupling is unique to individuals across multiple frequency bands: a graph signal processing study

Alessandra Griffa, Maria Giulia Preti

The relation between brain functional activity and the underlying structure is complex and varies depending on the specific brain region. Recently, we used graph signal processing to introduce the structural-decoupling index (SDI), a novel metric quantifyi ...

IEEE2022

Cortical and subcortical changes in resting-state neuronal activity and connectivity in early symptomatic ALS and advanced frontotemporal dementia

Alessandra Griffa

The objective of this study was to examine if patterns of resting-state brain activity and functional connectivity in cortical and subcortical regions in patients with early symptomatic amyotrophic lateral sclerosis (ALS) resemble those of behavioural vari ...

ELSEVIER SCI LTD2022

Brain structure-function coupling provides signatures for task decoding and individual fingerprinting

Dimitri Nestor Alice Van De Ville, Alessandra Griffa, Enrico Amico, Maria Giulia Preti, Raphaël Pierre Liégeois

Brain signatures of functional activity have shown promising results in both decoding brain states, meaning distinguishing between different tasks, and fingerprinting, that is identifying individuals within a large group. Importantly, these brain signature ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

The Biological Substrate of the Motoric Cognitive Risk Syndrome: A Pilot Study Using Amyloid-/Tau-PET and MR Imaging

Alessandra Griffa

We conducted a cross-sectional pilot study to explore the biological substrate of the Motoric Cognitive Risk (MCR) syndrome in a Memory Clinic cohort, using a multimodal imaging approach. Twenty participants were recruited and classified as MCR+/-. Amyloid ...

IOS PRESS2022

Alzheimer's Disease Biomarkers in Idiopathic Normal Pressure Hydrocephalus: Linking Functional Connectivity and Clinical Outcome

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Background: Alzheimer's disease (AD) pathology impacts the response to treatment in patients with idiopathic normal pressure hydrocephalus (iNPH), possibly through changes in resting-state functional connectivity (rs-FC). ...

IOS PRESS2021

Redox Dysregulation, Myelination Deficit and Dysconnectivity in Schizophrenia: A Translational Study in First Episode Patients and Experimental Models

Patric Hagmann, Rolf Gruetter, Lijing Xin, Alessandra Griffa

ELSEVIER SCIENCE INC2021

Magnetoencephalography Brain Signatures Relate to Cognition and Cognitive Reserve in the Oldest-Old: The EMIF-AD 90+Study

Alessandra Griffa

The oldest-old subjects represent the fastest growing segment of society and are at high risk for dementia with a prevalence of up to 40%. Lifestyle factors, such as lifelong participation in cognitive and leisure activities, may contribute to individual c ...

FRONTIERS MEDIA SA2021

Exploring MEG brain fingerprints: Evaluation, pitfalls, and interpretations

Dimitri Nestor Alice Van De Ville, Alessandra Griffa, Enrico Amico, Sélima Zahar, Ekansh Sareen

Individual characterization of subjects based on their functional connectome (FC), termed “FC fingerprinting”, has become a highly sought-after goal in contemporary neuroscience research. Recent functional magnetic resonance imaging (fMRI) studies have dem ...

2021

Fronto-Temporal Disconnection Within the Presence Hallucination Network in Psychotic Patients With Passivity Experiences

Patric Hagmann, Olaf Blanke, Alessandra Griffa, Pierre Progin, Giulio Rognini, Eva Blondiaux, Roy Salomon, Nathan Quentin Faivre, Jevita Potheegadoo, Giedre Stripeikyte, Kim Do

Psychosis, characterized by hallucinations and delusions, is a common feature of psychiatric disease, especially schizophrenia. One prominent theory posits that psychosis is driven by abnormal sensorimotor predictions leading to the misattribution of self- ...

2021

Additive and interaction effects of working memory and motor sequence training on brain functional connectivity

Patric Hagmann, Alessandra Griffa

Although shared behavioral and neural mechanisms between working memory (WM) and motor sequence learning (MSL) have been suggested, the additive and interactive effects of training have not been studied. This study aimed at investigating changes in brain f ...

Nature Portfolio2021

C-reactive protein and white matter microstructural changes in COVID-19 patients with encephalopathy

Alessandra Griffa

Encephalopathy is a neurological complication of COVID-19. The objective of this exploratory study is to investigate the link between systemic inflammation and brain microstructural changes (measured by diffusion-weighted imaging) in patients with COVID-19 ...

SPRINGER WIEN2021

Sensorimotor Induction of Auditory Misattribution in Early Psychosis

Patric Hagmann, Olaf Blanke, Alessandra Griffa, Pierre Progin, Giulio Rognini, Silvia Marchesotti, Roy Salomon, Andrea Serino, Fosco Bernasconi, Kim Do

Dysfunction of sensorimotor predictive processing is thought to underlie abnormalities in self-monitoring producing passivity symptoms in psychosis. Experimentally induced sensorimotor conflict can produce a failure in bodily self-monitoring (presence hall ...

2020

Editorial: Dynamic Functioning of Resting State Networks in Physiological and Pathological Conditions

Alessandra Griffa

FRONTIERS MEDIA SA2020

Dynamic functional networks in idiopathic normal pressure hydrocephalus: Alterations and reversibility by CSF tap test

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Idiopathic Normal Pressure Hydrocephalus (iNPH)-the leading cause of reversible dementia in aging-is characterized by ventriculomegaly and gait, cognitive and urinary impairments. Despite its high prevalence estimated at 6% among the elderlies, iNPH remain ...

Wiley2020

Redox Dysregulation, Myelination Deficit and Dysconnectivity in Schizophrenia: A Translational Study in First Episode Patients and Experimental Models

Patric Hagmann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Aline Monin, Emeline Mullier, Kim Do

ELSEVIER SCIENCE INC2020

Neural circuits of idiopathic Normal Pressure Hydrocephalus: A perspective review of brain connectivity and symptoms meta-analysis

Dimitri Nestor Alice Van De Ville, Alessandra Griffa

Idiopathic normal pressure hydrocephalus (iNPH) is a prevalent reversible neurological disorder characterized by impaired locomotion, cognition and urinary control with ventriculomegaly. Symptoms can be relieved with cerebrospinal fluid drainage, which mak ...

PERGAMON-ELSEVIER SCIENCE LTD2020

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