Recherche

Afficher tous les résultats pour

Accueil

Personne

Alessandra Griffa

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (82)

Default mode network and the timed up and go in MCI: A structural covariance analysis

Alessandra Griffa

Background: The timed up and go (TUG) is a test used to assess mobility in older adults and patients with neurological conditions. This study aims to compare brain gray matter (GM) correlates and structural covariance networks associated with the TUG time ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Dynamic spatiotemporal patterns of brain connectivity reorganize across development

Patric Hagmann, Marie Schaer, Alessandra Griffa, Emeline Mullier

Late human development is characterized by the maturation of high-level functional processes, which rely on reshaping of white matter connections, as well as synaptic density. However, the relationship between the whole-brain dynamics and the underlying wh ...

MIT PRESS2020

N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study

Patric Hagmann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Emeline Mullier, Kim Do

Background: There is increasing evidence that redox dysregulation, which can lead to oxidative stress and eventually to impairment of oligodendrocytes and parvalbumin interneurons, may underlie brain connectivity alterations in schizophrenia. Accordingly, ...

Oxford University Press (OUP)2019

The Bodily Self In Psychosis: Sensorimotor Induction Of Auditory Misattribution In Psychosis Is Linked To Neural Disconnectivity

Patric Hagmann, Olaf Blanke, Alessandra Griffa, Pierre Progin, Giulio Rognini, Silvia Marchesotti, Roy Salomon, Andrea Serino, Kim Do

OXFORD UNIV PRESS2019

Frontal cortical thickness correlates positively with impulsivity in early psychosis male patients

Alessandra Griffa, Kim Do

Aim Impulsive behaviours, which are frequent in young people suffering from psychosis have been linked to risky and violent behaviours and participate to the burden of psychotic illness. Given that morphological brain correlates of impulsivity in schizophr ...

WILEY2019

Sensorimotor Induction of Auditory Misattribution in Psychosis is Linked to Neural Disconnectivity

Patric Hagmann, Olaf Blanke, Alessandra Griffa, Pierre Progin, Giulio Rognini, Silvia Marchesotti, Roy Salomon, Andrea Serino, Kim Do

Background: Schneiderian first rank symptoms (FRS) are characterized by a diminished demarcation of self-other boundaries, causing misattribution of self-generated thoughts and actions to external sources. We have shown that introducing sensorimotor predic ...

2018

N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial

Patric Hagmann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Kim Do

Mechanism-based treatments for schizophrenia are needed, and increasing evidence suggests that oxidative stress may be a target. Previous research has shown that N-acetylcysteine (NAC), an antioxidant and glutathione (GSH) precursor almost devoid of side e ...

2018

Mapping higher-order relations between brain structure and function with embedded vector representations of connectomes

Patric Hagmann, Alessandra Griffa, Frantisek Vasa, Olaf Sporns

Nature Research2018

Network-Based Asymmetry of the Human Auditory System

Patric Hagmann, Alessandra Griffa, Olaf Sporns

Oxford University Press2018

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis

Patric Hagmann, Alessandra Griffa, Kim Do

Exposure to childhood trauma (CT) increases the risk for psychosis and affects the development of brain structures, possibly through oxidative stress. As oxidative stress is also linked to psychosis, it may interact with CT, leading to a more severe clinic ...

National Academy of Sciences2018

Redox Dysregulation, Oligodendrocytes And White Matter Alterations In Schizophrenia

Patric Hagmann, Lijing Xin, Alessandra Griffa, Kim Do

Oxford University Press2018

Childhood Trauma Engages Oxidative Stress, Hippocampus Alterations, And Poorer Clinical Outcome In Early Psychosis Patients

Patric Hagmann, Alessandra Griffa, Kim Do

Oxford University Press2018

Decreased integration and information capacity in stroke measured by whole brain models of resting state activity

Patric Hagmann, Alessandra Griffa

While several studies have shown that focal lesions affect the communication between structurally normal regions of the brain, and that these changes may correlate with behavioural deficits, their impact on brain's information processing capacity is curren ...

Oxford Univ Press2017

Exploring the role of white matter connectivity in cortex maturation

Patric Hagmann, Alessandra Griffa, Petra Susan Hüppi

The maturation of the cortical gray matter (GM) and white matter (WM) are described as sequential processes following multiple, but distinct rules. However, neither the mechanisms driving brain maturation processes, nor the relationship between GM and WM m ...

2017

Transient networks of spatio-temporal connectivity map communication pathways in brain functional systems

Jean-Philippe Thiran, Pierre Vandergheynst, Xavier Bresson, Patric Hagmann, Alessandra Griffa, Alessandro Daducci, Kirell Maël Benzi, Benjamin Ricaud

The study of brain dynamics enables us to characterize the time-varying functional connectivity among distinct neural groups. However, current methods suffer from the absence of structural connectivity information. We propose to integrate infra-slow neural ...

Elsevier2017

Brain network characterization of high-risk preterm-born school-age children

Jean-Philippe Thiran, François Lazeyras, Alessandra Griffa, Elda Fischi Gomez

Higher risk for long-term cognitive and behavioral impairments is one of the hallmarks of extreme prematurity (EP) and pregnancy-associated fetal adverse conditions such as intrauterine growth restriction (IUGR). While neurodevelopmental delay and abnormal ...

Elsevier Sci Ltd2016

An affected core drives network integration deficits of the structural connectome in 22q11.2 deletion syndrome

Patric Hagmann, Marie Schaer, Alessandra Griffa, Frantisek Vasa

Chromosome 22q11.2 deletion syndrome (22q11DS) is a genetic disease known to lead to cerebral structural alterations, which we study using the framework of the macroscopic white-matter connectome. We create weighted connectomes of 44 patients with 22q11DS ...

Elsevier Sci Ltd2016

Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients

Jean-Philippe Thiran, Patric Hagmann, Philipp Baumann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Aline Monin, Kim Do

Schizophrenia pathophysiology implies both abnormal redox control and dysconnectivity of the prefrontal cortex, partly related to oligodendrocyte and myelin impairments. As oligodendrocytes are highly vulnerable to altered redox state, we investigated the ...

Nature Publishing Group2015

Evidence From Imaging Studies For Oxidative Stress Mechanisms In First Episode Schizophrenia

Jean-Philippe Thiran, Patric Hagmann, Rolf Gruetter, Lijing Xin, João Miguel das Neves Duarte, Alessandra Griffa, Yohan Van de Looij, Alexander Monin, Alberto Corcoba, Kim Do

Oxford Univ Press2015

The topology of structural brain connectivity in diseases and spatio-temporal connectomics

Alessandra Griffa

The brain is a complex system, composed of multiple neural units interconnected at different spatial and temporal scales. Diffusion MRI allows probing in vivo the anatomical connectivity between different cortical areas through white matter tracts. In para ...

EPFL2015

Page 3 sur 5