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Philippe Renaud

Cette personne a quitté l’EPFL

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Publications associées (301)

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Increasing PCR sensitivity by removal of polymerase inhibitors in environmental samples by using dielectrophoresis

Philippe Renaud, Rodrigo Martinez Duarte

Dielectrophoresis (DEP) is a powerful tool to manipulate cells and molecules in microfluidic chips. However, few practical applications using DEP exist. An immediate practical application of a carbon- electrode DEP system, in removing PCR inhibitors from a ...

Elsevier2013

Modeling, Simulation, and Performance Evaluation of a Novel Microfluidic Impedance Cytometer for Morphology-Based Cell Discrimination

Philippe Renaud, Ludovica Colella, Marjan Shaker

The performance of a novel microfluidic impedance cytometer [1] for single-cell analysis is investigated in-silico by means of a finite element model. The main feature of the device is the ability to probe impedance of flowing cells along two orthogonal di ...

Institute of Electrical and Electronics Engineers2014

Neural probe combining microelectrodes and a droplet-based microdialysis collection system for high temporal resolution sampling

Philippe Renaud, Arnaud Bertsch, Guillaume Cédric Yves Petitpierre

We propose a novel neural probe which combines microfluidic channels with recording and stimulation electrodes. The developed microfabrication approach enables the concentration of every active element such as electrodes and the sampling inlet in close pro ...

Royal Society of Chemistry2016

Ultrathin Alumina Membranes as Scaffold for Epithelial Cell Culture from the Intestine of Rainbow Trout

Philippe Renaud, Songmei Wu, Kristin Schirmer, Carolin Drieschner

Permeable membranes are indispensable for in vitro epithelial barrier models. However, currently available polymer-based membranes are low in porosity and relatively thick, resulting in a limited permeability and unrealistic culture conditions. In this stu ...

Amer Chemical Soc2017

Advances in the design of macroporous polymer scaffolds for potential applications in dentistry

Philippe Renaud, Thomas Michael Braschler

A paradigm shift is taking place in medicine and dentistry from using synthetic implants and tissue grafts to a tissue engineering approach that uses degradable porous three-dimensional (3D) material hydrogels integrated with cells and bioactive factors to ...

2013

Fast 10-µs Microelectromechanical Optical Switch inside Planar Hollow Waveguide (PHW)

Philippe Renaud, Roland Guerre

A new concept for a 1 × 2 micromechanical optical switch with 10 μs of switching speed, 29 dB of ON/OFF ratio, and insertion loss of −7.22 dB for λ = 1550 nm and −4.96 dB for λ = 635 nm is presented. The idea is to insert a micromechanical switching mechan ...

IEEE Institute of Electrical and Electronics Engineers2006

A miniaturized continuous dielectrophoretic cell sorter and its applications

Philippe Renaud, Thomas Michael Braschler, Nicolas Demierre, Ana Valero

There is great interest in highly sensitive separation methods capable of quickly isolating a particular cell type within a single manipulation step prior to their analysis. We present a cell sorting device based on the opposition of dielectrophoretic forc ...

American Institute of Physics2010

Temperature measurements in microfluidic systems: Heat dissipation of negative dielectrophoresis barriers

Marilia Panayiotou, Philippe Renaud, Martin Jordan, Urban Seger

The manipulation of living biological cells in microfluidic channels by a combination of negative dielectrophoretic barriers and pressure-driven flows is widely employed in lab-on-a-chip systems. However, electric fields in conducting media induce Joule he ...

2005

First steps toward noninvasive intraocular pressure monitoring with a sensing contact lens

Philippe Renaud, Arnaud Bertsch, Matteo Leonardi

PURPOSE. To present a novel and minimally invasive approach to intraocular pressure (IOP) monitoring based on a sensing contact lens. METHODS. The key element of this measurement method is a soft contact lens with an embedded microfabricated strain gauge a ...

2004

Passive flow control valve for protein delivery

Philippe Renaud, Harald Van Lintel

Passive ow control valves are usually intended to deliver or drain a uid at a constant rate independently of pressure variations. Micro uidic devices made of a stack of two plates are considered here: the rst plate comprises a exible silicon membrane havin ...

2017

Fabrication and test of implantable thin-film electrodes for stimulation and recording of biological signals

Philippe Renaud, Stefan Metz, Raphael Holzer

The fabrication, characterization and application of polyimide-based flexible microelectrodes for recording from and stimulation of biological tissue are described. The planar electrodes consist of a polyimide-platinum-polyimide sandwich structure with a t ...

2000

A microfluidic approach to synthesizing high-performance microfibers with tunable anhydrous proton conductivity

Philippe Renaud, Arnaud Bertsch, Mohammad Mahdi Hasani-Sadrabadi, Jules John Vandersarl

Here, we demonstrate a new approach for the synthesis of ion exchange microfibers with finely tuned anhydrous conductivity. This work presents microfluidics as a system to control the size and phosphoric acid (PA) doping level of the polybenzimidazole (PBI ...

Royal Society of Chemistry2013

Intracellular Recording of Cardiomyocyte Action Potentials with Nanopatterned Volcano-Shaped Microelectrode Arrays

Philippe Renaud, Arnaud Bertsch, Benoît Xavier Emmanuel Desbiolles

Micronanotechnology-based multielectrode ar- rays have led to remarkable progress in the field of transmembrane voltage recording of excitable cells. However, providing long-term optoporation- or electroporation-free intracellular access remains a consider ...

American Chemical Society (ACS)2019

Partial release and detachment of microfabricated metal and polymer structures by anodic metal dissolution

Philippe Renaud, Arnaud Bertsch, Stefan Metz

The large majority of microelectromechanical systems (MEMS) are fabricated on silicon, glass or Pyrex substrates by manufacturing techniques, which originated from the semiconductors industry. However, their final application often requires removal of the ...

Institute of Electrical and Electronics Engineers2005

Single cell isolation process with laser induced forward transfer

Philippe Renaud, Yu Deng

Background A viable single cell is crucial for studies of single cell biology. In this paper, laser-induced forward transfer (LIFT) was used to isolate individual cell with a closed chamber designed to avoid contamination and maintain humidity. Hela cells ...

Biomed Central Ltd2017

Very High Throughput Electrical Cell Lysis and Extraction of Intracellular Compounds Using 3D Carbon Electrodes in Lab-on-a-Chip Devices

Rodrigo Martinez Duarte, Philippe Renaud, Freddy Radtke, Rajwinder Lehal

Here we present an electrical lysis throughput of 600 microliters per minute at high cell density (108 yeast cells per ml) with 90% efficiency, thus improving the current common throughput of one microliter per minute. We also demonstrate the extraction of ...

2012

Optimization of microfluidic single cell trapping for long-term on-chip culture

Philippe Renaud, Matthias Lütolf, Ana Valero, Stefan Kobel

The poor efficiency of microfluidic single cell trapping is currently restricting the full potential of state-of-the-art single cell analyses. Using fluid dynamics simulations in combination with particle image velocimetry to systematically optimize trap a ...

Royal Society of Chemistry2010

Experimental study of electrical breakdown in MEMS devices with micrometer scale gaps

Philippe Renaud, Herbert Shea

We present an experimental study of the DC breakdown voltage of MEMS interdigitated aluminum electrodes with gaps ranging from 10 to 500 μm. Unlike most research on MEMS electrodes that was done at atmospheric pressure, our work has focused on the effect o ...

2008

Implantable and wearable measurement system for smart knee prosthesis

Kamiar Aminian, Philippe Renaud, Arash Arami, David Forchelet

In this work we present the implantable and wearable measurement system developed for smart knee prostheses monitoring. The kinematic measurement system contains three anisotropic magnetoresistive sensors embedded into the polyethylene part of the prosthes ...

IEEE2014

Materials for neural interfaces

Philippe Renaud

The treatment of disorders of the nervous system poses a major clinical challenge. Development of neuromodulation (i.e., interfacing electronics to nervous tissue to modulate its function) has provided patients with neuronal-related deficits a new tool to ...

2012