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Philippe Renaud

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Publications associées (301)

Ion beam etching redeposition for 3D multimaterial nanostructure manufacturing

Philippe Renaud, Arnaud Bertsch, Benoît Xavier Emmanuel Desbiolles

A novel fabrication method based on the local sputtering of photoresist sidewalls during ion beam etching is presented. This method allows for the manufacture of three-dimensional multimaterial nanostructures at the wafer scale in only four process steps. ...

2019

Micropipette calibration by differential pressure measurements

Philippe Renaud, David Vincent Bonzon

The pipetting of small volumes, typically ranging between a few and one thousand microliters (mu l), is widely used in many laboratories and essentially relies on air displacement to aspirate and dispense the liquid contained in a small plastic tip. ...

IOP PUBLISHING LTD2019

Dielectrophoresis‐assisted creation of cell aggregates under flow conditions using planar electrodes

Philippe Renaud, Harald Van Lintel, Soufian Lasli, Jonathan Bastien Cottet

We present a microfluidic platform allowing dielectrophoresis-assisted formation of cell aggregates of controlled size and composition under flow conditions. When specific ex- perimental conditions are met, negative dielectrophoresis allows efficient conce ...

2019

Particle suitable for the manufacture of an implantable soft tissue engineering material

Philippe Renaud, Thomas Michael Braschler, Amélie Barbara Hildegarde Béduer

The particle (1) is suitable for the manufacture of an implantable soft tissue engineering material and comprises: a three-dimensionally warped and branched sheet (2) where (i) the three-dimensionally warped and branched sheet (2) is made from a biocompati ...

2019

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF

Philippe Renaud, Kristin Schirmer, Carolin Drieschner, Hannah Inka Schug

An in vitro model of the fish intestine is of interest for research and application in diverse fields such as fish physiology, aquaculture and chemical risk assessment. The recently developed epithelial barrier model of the fish intestine relies on the RTg ...

Springer2019

Efficacy of pulsed electromagnetic fields and electromagnetic fields tuned to the ion cyclotron resonance frequency of Ca2+ on chondrogenic differentiation

Philippe Renaud, Harald Van Lintel, Hanie Kavand

Previous studies provide strong evidence for the therapeutic effect of electromagnetic fields (EMFs) on different tissues including cartilage. Diverse exposure parameters applied in scientific reports and the unknown interacting mechanism of EMF with biolo ...

WILEY2019

Analysis of patient-specific stimulation with segmented leads in the subthalamic nucleus

Philippe Renaud, André Mercanzini, Thuy Anh Khoa Nguyen

Objective Segmented deep brain stimulation leads in the subthalamic nucleus have shown to increase therapeutic window using directional stimulation. However, it is not fully understood how these segmented leads with reduced electrode size modify the volume ...

PUBLIC LIBRARY SCIENCE2019

Steerable device and system

Philippe Renaud, Marc Jasper Boers, Guillaume Cédric Yves Petitpierre

A steerable device for use as e.g. a guidewire for insertion into a subject's body is disclosed. The device features a single side deflection of a bendable portion located at its distal end by application of a longitudinally-directed force either on an inn ...

2019

Cell-Imprint Surface Modification by Contact Photolithography-Based Approaches: Direct-Cell Photolithography and Optical Soft Lithography Using PDMS Cell Imprints

Philippe Renaud, Harald Van Lintel, Shahin Bonakdar, Hanie Kavand

New cell-imprint surface modification techniques based on direct-cell photolithography and optical soft lithography using poly(dimethylsiloxane) (PDMS) cell imprints are presented for enhanced cell-based studies. The core concept of engineering materials f ...

AMER CHEMICAL SOC2019

Intracellular Recording of Cardiomyocyte Action Potentials with Nanopatterned Volcano-Shaped Microelectrode Arrays

Philippe Renaud, Arnaud Bertsch, Benoît Xavier Emmanuel Desbiolles

Micronanotechnology-based multielectrode ar- rays have led to remarkable progress in the field of transmembrane voltage recording of excitable cells. However, providing long-term optoporation- or electroporation-free intracellular access remains a consider ...

American Chemical Society (ACS)2019

MyDEP: A New Computational Tool For Dielectric Modeling Of Particles And Cells

Philippe Renaud, Jonathan Bastien Cottet

Before performing experiments in the lab with dielectrophoresis (DEP), it is useful to predict the particle and cell responses to the electric field. This requires knowledge of particles or cells properties, which can be obtained from the literature, and i ...

2018

Impedance-based real-time position sensor for lab-on-a-chip devices

Philippe Renaud, Harald Van Lintel, Jonathan Bastien Cottet

This paper presents the theoretical and experimental development of an integrated position sensor for lab-on-a-chip devices. The interest for single cell analysis is growing. However, this requires monitoring and controlling cell displacements in real time ...

2018

Label-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells

Philippe Renaud, Sandro Carrara, Tugba Kilic, Ana Teresa De Sousa Valinhas

Nanoscale extracellular vesicles (EVs) including exosomes (50–150 nm membrane particles) have emerged as promising cancer biomarkers due to the carried genetic information about the parental cells. However the sensitive detection of these vesicles remains ...

Nature Research2018

Separation of blood microsamples by exploiting sedimentation at the microscale

Philippe Renaud, David Forchelet

Microsample analysis is highly bene cial in blood-based testing where cutting-edge bioanalytical technologies enable the analysis of volumes down to a few tens of microliters. Despite the availability of analytical methods, the di culty in obtaining high-q ...

Nature Research2018

Microfluidics: A New Layer of Control for Extrusion-Based 3D Printing

Philippe Renaud, Arnaud Bertsch, Ludovic Serex

Advances in 3D printing have enabled the use of this technology in a growing number of fields, and have started to spark the interest of biologists. Having the particularity of being cell friendly and allowing multimaterial deposition, extrusion-based 3D p ...

2018

Pore Size Manipulation in 3D Printed Cryogels Enables Selective Cell Seeding

Philippe Renaud, Arnaud Bertsch, Ariane Rochat, Thomas Michael Braschler, Ludovic Serex, Amélie Barbara Hildegarde Béduer, Aleksandra Filippova

Cryogels are macroporous materials that display remarkable properties, such as high pore interconnection, large surface to volume ratio, and high mechanical stability, making them good candidates for 3D cell culture. However, shaping cryogels remains chall ...

Wiley2018

Additive manufacturing of hierarchical injectable scaffolds for tissue engineering

Philippe Renaud, Thomas Michael Braschler, Niccolo Piacentini

We present a 3D-printing technology allowing free-form fabrication of centimetre-scale injectable structures for minimally invasive delivery. They result from the combination of 3D printing onto a cryogenic substrate and optimisation of carboxymethylcellul ...

2018

Organs-on-chip monitoring: sensors and other strategies

Philippe Renaud, Sandro Carrara, Fatemeh Navaee, Francesca Stradolini, Tugba Kilic

As a paradigm shifting player of tissue engineering, organs-on-chips (OOCs) are considered to hold great potential for future “clinical trials on chip” as well as a step forward to design personalized medicine. Despite all ethical concerns raised by commun ...

2018

Tip connector for fluidic and electrical connection

Philippe Renaud, Yann Barrandon, David Vincent Bonzon, Georges Muller, Jean-Baptiste Bureau, David Forchelet, Nicolas Uffer

A connector for providing both a fluidic and electrical connection is disclosed, said connector having a proximal end, a distal end and an elongated body in between, characterized in that the elongated body has an inner cavity spanning throughout its lengt ...

2018

Cryogel 3d scaffolds and methods for producing thereof

Philippe Renaud, Thomas Michael Braschler, Amélie Barbara Hildegarde Béduer

A method of producing a cryogel-based multicompartment 3D scaffold is herein disclosed. The method comprises the steps of: a) providing a first frozen polymeric layer on a refrigerated support kept at subzero temperature; b) providing subsequent polymeric ...

2018

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