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Philippe Renaud

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Publications associées (301)

Focusing and continuous separation of cells in a microfluidic device using lateral dielectrophoresis

Philippe Renaud, Randoald Müller, Nicolas Demierre, Thomas Michael Braschler

We have fabricated a microfluidic device based on a novel geometrical arrangement of lateral metal electrodes and a patterned insulator. Our device combines the concept of insulator-based “electrodeless” dielectrophoresis with multiple frequencies to achie ...

2008

Cell culture imaging using microimpedance tomography

Philippe Renaud, Olof Pontus Linderholm

We present a novel, inexpensive, and fast microimpedance tomography system for two-dimensional imaging of cell and tissue cultures. The system is based on four-electrode measurements using 16 planar microelectrodes (5 mum x 4 mm) integrated into a culture ...

2008

In-Plane Silicon-On-Nothing Nanometer-Scale Resonant Suspended Gate MOSFET for In-IC Integration Perspectives

Philippe Renaud, Mihai Adrian Ionescu, Nicolas Abelé

A 14-MHz in-plane nanoelectromechanical resonator based on a resonant-suspended-gate (RSG) MOSFET principle and integrated in a front-end process is demonstrated. The devices are in-plane flexural vibration mode beams (L = 10 mum, w = 165 nm, and h = 400 n ...

Institute of Electrical and Electronics Engineers2008

A telemetric pressure sensor system for biomedical applications

Philippe Renaud

A new implantable pressure sensor for long-term monitoring of intracranial pressure is presented. The sensor is powered by telemetry and can be interrogated wirelessly. A capacitive pressure transducer, whose capacitance is converted to a frequency-encoded ...

2008

Dielectrophoretic sorting on a microfabricated flow cytometer: Label free separation of Babesia bovis infected erythrocytes

Philippe Renaud, Nicolas Demierre, Thomas Michael Braschler

Dielectrophoresis is a method that has demonstrated great potential in cell discrimination and isolation. In this study, the dielectrophoretic sorting of normal and Babesia bovis infected erythrocytes was performed using a microfabricated flow cytometer. S ...

2008

Demonstration of cortical recording using novel flexible polymer neural probes

Philippe Renaud, Arnaud Bertsch, Marc Jasper Boers, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun, Karen Cheung

We present the fabrication, characterization, use in cortical recording and histological results of a flexible implantable neural probe. The microfabricated device is implemented in polyimide and platinum providing mechanical flexibility, high quality elec ...

2008

Continuous separation of cells by balanced dielectrophoretic forces at multiple frequencies

Philippe Renaud, Nicolas Demierre, Thomas Michael Braschler

We present a particle-sorting device based on the opposition of dielectrophoretic forces. The forces are generated by an array of electrode chambers located in both sidewalls of a main flow channel. Particles with different dielectric response perceive dif ...

2008

Rapid Immunoassay Using Steady-State Dispersion Effects in Nanochannels

Philippe Renaud, Nicolas Durand, Ana Valero

We present a novel method for on-chip competitive dispersion immunoassay (DISIA) which aims at measuring the specificity between fluorescently-labeled antibodies (Ab*) and label-free antigens (Ag). We have fabricated a nanofluidic device that allows fast d ...

2008

A virtual valve for smooth contamination-free flow switching

Philippe Renaud, Mario Schlund, Harald Van Lintel, Nicolas Demierre, Joël Theytaz, Raphaël Tornay, Thomas Michael Braschler, Anja Kunze, Grazia Loche

We present a channel geometry that allows for clean switching between different inlets of a microchip without any contamination of the inlets or the downstream flow. We drive this virtual valve with a pneumatic pressure setup that minimizes disturbance of ...

2007

Characterization and optimization of liquid electrodes for lateral dielectrophoresis

Philippe Renaud, Harald Van Lintel, Nicolas Demierre, Urban Seger, Olof Pontus Linderholm, Thomas Michael Braschler

Using the concept of insulator-based "electrodeless" dielectrophoresis, we present a novel geometry for shaping electric fields to achieve lateral deviation of particles in liquid flows. The field is generated by lateral planar metal electrodes and is guid ...

2007

Apparatus for manipulating, modifying and characterizing particles in a micro channel

Philippe Renaud, Nicolas Demierre, Urban Seger, Olof Pontus Linderholm, Thomas Michael Braschler

Microfluidic system comprising a space (0207) for containing a liquid and at least one lateral chamber (0201) in communication with said space, said lateral chamber containing a metal electrode (0204). The lateral chamber and the space are designed to be f ...

2007

Electrical detection and ejection of beads in a one-cell-per-drop microdispenser

Philippe Renaud, Raphaël Tornay

2007

A simple pneumatic setup for driving microfluidics

Philippe Renaud, Harald Van Lintel, Nicolas Demierre, Joël Theytaz, Lynda Metref, Thomas Michael Braschler

2007

Retinal Prosthesis : Testing Prototypes on a Dystrophic Rat Retina

Philippe Renaud, Olof Pontus Linderholm, Sri Harsha Kasi Raj

2007

Direct Measurement of Effective Diffusion Coefficients in Nanochannels Using Steady-State Dispersion Effects

Philippe Renaud, Arnaud Bertsch, Mina Todorova, Nicolas Durand

We present a method to measure effective diffusion coefficients of fluorescently labeled molecules inside a nanofluidic system. Molecules with small diffusion coefficients show a larger lateral dispersion than highly diffusive species, which is counterintu ...

American Institute of Physics2007

Combining multiple optical trapping with microflow manipulation for the rapid bioanalytics on microparticles in a chip

Guy Delacrétaz, René Salathé, Philippe Renaud, Johann Rohner, Fabrice Merenda, Gerben Boer

An array of four independent laser traps is combined with a polydimethylsiloxane microfluidic chip to form a very compact system allowing parallel processing of biological objects. Strong three dimensional trapping allows holding objects such as functional ...

American Institute of Physics2007

Microfluidic patterning of alginate hydrogels

Philippe Renaud

In this article the authors present techniques which allow the microfluidic design of alginate microgels with layer composition on a chip. The hydrogel is created by combining two laminar flows of the gel precursor solutions-a calcium solution and an algin ...

American Vacuum Society2007

Demonstration of cortical recording and reduced inflammatory response using flexible polymer neural probes

Philippe Renaud, Arnaud Bertsch, Marc Jasper Boers, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun, Karen Cheung

2007

Assessment on Enucleated Pig Eyes of a Minimally Invasive Contact Lens Sensor for IOP Monitoring

Matteo Leonardi, André Mermoud, Philippe Renaud, Arnaud Bertsch

2007

Bipolar resistivity profiling of 3D tissue culture

Philippe Renaud, Jonas Vannod, Yann Barrandon, Olof Pontus Linderholm

We describe a new low-cost technique for continuous monitoring of the thickness of biofilms and tissue cultures, and we demonstrate the advantage of using electrodes of different dimensions to probe different depths of a sample. We have used electric imped ...

Elsevier2007

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