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Philippe Renaud

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Publications associées (301)

Continuous sampling and analysis by on-chip liquid/solid chromatography

Philippe Renaud, Mario Schlund, Silvan Schnydrig

This paper describes a lab-on-a-chip device for continuous liquid/solid chromatography measurements. Chromatographic separations of phenolic test solutions as well as of vitamins are illustrating the ability and versatility of the system. The dependence of ...

2007

Controlled Release Drug Coatings on Flexible Neural Probes

Philippe Renaud, Arnaud Bertsch, Jeffrey Alan Hubbell, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun

We present the development, characterization and in vivo validation of a novel drug eluting coating that has been applied to flexible neural probes. The coating consists of drug eluting nanoparticles loaded with an anti-inflammatory drug embedded in a biod ...

2007

Contraction measurements of cardiomyocytes grown on silicon cantilevers

Philippe Renaud, Arnaud Bertsch, Mina Todorova, Philipp Stücklin

2007

Label-free detection of Babesia bovis infected red blood cells using impedance spectroscopy on microfabricated flow cytometer

Philippe Renaud, Nicolas Demierre, Thomas Michael Braschler

Impedance spectroscopy is a powerful tool for label-free analysis and characterisation of living cells. In this work, we achieved the detection of Babesia bovis infected red blood cells using impedance spectroscopy on a microfabricated flow cytometer. The ...

2007

The effect of biodegradable drug release coatings on the electrical characteristrics of neural electrodes

Philippe Renaud, Arnaud Bertsch, Marc Jasper Boers, Jeffrey Alan Hubbell, André Mercanzini

2007

Continuous separation of cells in a microfluidic device using lateral dielectrophoresis

Philippe Renaud, Nicolas Demierre, Thomas Michael Braschler

2007

Flexible polyimide microelectrode array for in vivo recordings and current source density analysis

Philippe Renaud, Karen Cheung

This work presents implantable, flexible polymer-based probes with embedded microelectrodes for acute and chronic neural recordings in vivo, as tested on rodents. Acute recordings using this array were done in mice under urethane anesthesia and compared to ...

Elsevier2007

Creating structures at the scale of cells on the fly: gentle single cell entrapment on chip

Philippe Renaud, Nicolas Demierre, Urban Seger, Olof Pontus Linderholm, Thomas Michael Braschler

2007

BioMEMS for medicine: On-chip cell characterization and implantable microelectrodes

Philippe Renaud, Karen Cheung

This paper surveys a few of the emerging bioMEMS technologies at EPFL for improved, inexpensive health care. The lab-on-a-chip systems use dielectrophoretic forces to direct cell movement within microfluidic networks and impedance spectroscopy for label-fr ...

2006

SU-8 nanocomposite photoresist with low stress properties for microfabrication applications

Heinrich Hofmann, Philippe Renaud, Arnaud Bertsch, Sébastien Jiguet

2006

On-chip extrusion of lipid vesicles and tubes through microsized apertures

Philippe Renaud

In this work we present the formation of micrometre-sized lipid vesicles and tubes with perfectly homogeneous diameter and extraordinary length. The method is a novel approach for unconventional fabrication of soft-matter microstructured devices based on t ...

2006

Two-dimensional impedance imaging of cell migration and epithelial stratification

Philippe Renaud, Jonas Vannod, Yann Barrandon, Olof Pontus Linderholm, Thomas Michael Braschler

We present a miniaturized impedance imaging system, developed for 2D imaging of cell and tissue culture. The system is based on 16 microelectrodes (5 µm × 4 mm). An equivalent circuit for four-point (tetrapolar) impedance spectra was developed and validate ...

2006

Analytical expression for electric filed between two facing strip electrodes in microchannels

Philippe Renaud, Urban Seger, Olof Pontus Linderholm

An analytical solution is presented for the electric field between two facing strip electrodes situated in a microchannel, as frequently used in impedance cytometry applications. The measured change in resistance as induced by a 5 mm bead moving through th ...

2006

Effect of filler behavior on nanocomposite SU8 photoresist for moving micro- parts

Stefano Mischler, Philippe Renaud, Arnaud Bertsch, Sébastien Jiguet

The use of low-stress SU8 nanocomposites as a functional material for micro- parts and coating applications is described in this paper. It was found that the nanoparticles lower the internal stress and decrease the wear rate and frictional coefficient of t ...

2006

SU-8 nanocomposite coatings with improved tribological performance for MEMS

Heinrich Hofmann, Stefano Mischler, Philippe Renaud, Arnaud Bertsch, Sébastien Jiguet

The increasing interests in micro-electro-mechanical systems (MEMS) has raised the requirement for photoresist materials with improved friction and wear properties for mechanically loaded 3D shaped microstructures. In this work, SU8 photoresist layers rein ...

2006

Fast 10-µs Microelectromechanical Optical Switch inside Planar Hollow Waveguide (PHW)

Philippe Renaud, Roland Guerre

A new concept for a 1 × 2 micromechanical optical switch with 10 μs of switching speed, 29 dB of ON/OFF ratio, and insertion loss of −7.22 dB for λ = 1550 nm and −4.96 dB for λ = 635 nm is presented. The idea is to insert a micromechanical switching mechan ...

IEEE Institute of Electrical and Electronics Engineers2006

Subretinal electrode implantation in the P23H rat for chronic stimulations

Philippe Renaud, Olof Pontus Linderholm

Background: In age related macular degeneration and inherited dystrophies, preservation of retinal ganglion cells has been demonstrated. This finding has led to the development of various models of subretinal or epiretinal implant in order to restore visio ...

2006

pH Controlled Diffusion of Proteins with Different pI Values across a Nanochannel on a Chip

Philippe Renaud, Arnaud Bertsch, Reto Bruno Schoch

Electrostatic interactions dominate the diffusion of proteins in a nanochannel, which was measured and modeled for pH values above and below the isoelectric points of three lectin proteins. Maximal diffusion coefficients were obtained when the proteins wer ...

American Chemical Society (ACS)2006

Device for dispensing microfluidic droplets, particularly for cytometry

Philippe Renaud

The invention relates to a device for dispensing droplets comprising a first channel (8, 10), known as the main channel, for circulating a first liquid flow, a second channel (12, 13) for circulating fluid, forming an intersection area (27) with the first ...

2005

Comment on AC frequency characteristics of coplanar impedance sensors as design parameters by Jongin Hong, Dae Sung Yoon, Sung Kwan Kim, Tae Song Kim, Sanghyo Kim, Eugene Y. Pak and Kwangsoo No, Lab Chip, 2005, 5, 270

Philippe Renaud, Olof Pontus Linderholm

In their article, ‘‘AC frequency characteristics of coplanar impedance sensors as design parameters’’, Hong et al.1 present an analytical model for the calculation of the resistance between two electrodes in a microchannel. However, their measurements fit ...

2005

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