Publications de Alexandre Terrier

Publications associées (111)

A flow sensing model for mesenchymal stromal cells using morphogen dynamics

Dominique Pioletti, Alexandre Terrier, Miguel Gortchacow

The differentiation of mesenchymal stromal cells has been shown to be af- fected by many parameters such as morphogens, flow rate, medium viscosity, and shear stress when exposed to fluid flow. The mechanism by which these cells sense their environment is ...

Elsevier2013

A musculoskeletal shoulder model based on pseudo-inverse and null-space optimization

Dominique Pioletti, Denis Gillet, Alexandre Terrier, Alain Farron, Philippe Müllhaupt

The goal of the present work was assess the feasibility of using a pseudo-inverse and null-space optimization approach in the modeling of the shoulder biomechanics. The method was applied to a simplified musculoskeletal shoulder model. The mechanical syste ...

Elsevier2010

Micromotion-induced peri-prosthetic fluid flow around a cementless femoral stem

Dominique Pioletti, Alexandre Terrier, Valérie Hélène Emilie Malfroy Camine

Micromotion-induced interstitial fluid flow at the bone-implant interface has been proposed to play an important role in aseptic loosening of cementless implants. High fluid velocities are thought to promote aseptic loosening through activation of osteocla ...

Taylor & Francis2017

Prediction of bone density around orthopedic implants delivering bisphosphonate

Dominique Pioletti, Alexandre Terrier, Vincent Stadelmann

The fixation of an orthopedic implant depends strongly upon its initial stability. Peri-implant bone may resorb shortly after the surgery. This resorbtion is directly followed by new bone formation and implants fixation strengthening, the so-called seconda ...

2009

A framework for forward-dynamics simulation of the human shoulder

Dominique Pioletti, Alexandre Terrier, Philippe Müllhaupt, Alain Farron, Ehsan Sarshari

A vast majority of the available biomechanical models of the human shoulder has been developed based on inverse dynamics, e.g. [1,2]. This imposes a number of limitations on their application. For instance, the glenohumeral joint is approximated as an idea ...

2016

Cement stress predictions after anatomic total shoulder arthroplasty are correlated with preoperative glenoid bone quality

Alexandre Terrier, Alain Farron, Raphaël Rodolphe Obrist

Hypothesis: We hypothesized that biomechanical parameters typically associated with glenoid implant failure after anatomic total shoulder arthroplasty (aTSA) would be correlated with preoperative glenoid bone quality. Methods: We developed an objective aut ...

Elsevier2017

Three-dimensional evaluation of the transverse rotator cuff muscle's resultant force angle in relation to scapulohumeral subluxation and glenoid vault morphology in nonpathological shoulders

Alexandre Terrier, Alain Farron, Patrick Goetti, Pezhman Eghbalishamsabadi, Matthieu Boubat

Background: Static posterior subluxation of the humeral head (SPSH) results in glenohumeral osteoarthritis. Treatment strategies for SPSH with or without resulting osteoarthritis remain challenging. There is growing interest in evaluating the rotator cuff ...

Mosby-Elsevier2024

Muscle co-contraction in an upper limb musculoskeletal model: EMG-assisted vs. standard load-sharing

Dominique Pioletti, Alexandre Terrier, Alain Farron, Philippe Müllhaupt, Ehsan Sarshari, Matteo Mancuso

Estimation of muscle forces in over-actuated musculoskeletal models involves optimal distributions of net joint moments among muscles by a standard load-sharing scheme (SLS). Given that co-contractions of antagonistic muscles are counterproductive in the n ...

2021

Predicting Transdermal Fentanyl Delivery Using Mechanistic Simulations for Tailored Therapy

Alexandre Terrier

Transdermal drug delivery is a key technology for administering drugs. However, most devices are "one-size-fits-all", even though drug diffusion through the skin varies significantly from person-to-person. For next-generation devices, personalization for o ...

FRONTIERS MEDIA SA2020

Influence of smoking on the healing of conservatively treated displaced midshaft clavicle fractures a systematic review and meta-analysis

Alexandre Terrier

Aims Tobacco, in addition to being one of the greatest public health threats facing our world, is believed to have deleterious effects on bone metabolism and especially on bone healing. It has been described in the literature that patients who smoke are ap ...

BRITISH EDITORIAL SOC BONE & JOINT SURGERY2023

Causal associations between scapular morphology and shoulder condition estimated with Bayesian statistics

Dominique Pioletti, Alexandre Terrier, Philippe Büchler

Background and Objective: While there is a reported correlation between shoulder condition and scapular morphology, the precise impact of typical anatomical variables remains a subject of ongoing debate. This study aimed to evaluate this causal association ...

2025

Is preoperative glenoid bone mineral density associated with aseptic glenoid implant loosening in anatomic total shoulder arthroplasty?

Alexandre Terrier, Raphaël Rodolphe Obrist

BackgroundAseptic loosening of glenoid implants is the primary revision cause in anatomic total shoulder arthroplasty (aTSA). While supported by biomechanical studies, the impact of glenoid bone quality, more specifically bone mineral density (BMD), on ase ...

2021

Comparison of polyethylene wear in anatomical and reversed shoulder prostheses

Dominique Pioletti, Alexandre Terrier, Alain Farron, Francesco Merlini

Wear of polyethylene is associated with aseptic loosening of orthopaedic implants and has been observed in hip and knee prostheses and anatomical implants for the shoulder. The reversed shoulder prostheses have not been assessed as yet. We investigated the ...

2009

Automated CT bone segmentation using statistical shape modelling and local template matching

Alexandre Terrier, Alain Farron, Philippe Büchler

Accurate CT bone segmentation is essential to develop chair-side manufacturing of implants based on additive manufacturing. We herewith present an automated method able to accurately segment challenging bone regions, while simultaneously providing anatomic ...

2019

Osteoclastogenesis can be mechanically-induced in the peri-implant bone

Dominique Pioletti, Alexandre Terrier, Vincent Stadelmann

Total joint replacements are highly successful in relieving pain and restoring movement of damaged joints. However, the lifespan of the implants is limited. The implant’s long-term stability depends largely on the preservation of periprosthetic bone. Debri ...

2009

Predrilled locking compression plate is more accurate than tension band wiring in restoring articular geometry of the ulnar greater sigmoid notch after olecranon Chevron osteotomy

Alexandre Terrier, Patrick Goetti, Frédéric Vauclair

Introduction: The olecranon Chevron osteotomy (OCO) is commonly used to approach complex intraarticular fractures of the distal humerus. Predrilled tension band wiring (TBW) has historically been used to fix OCO. However, clinical outcomes are burdened by ...

ELSEVIER SCI LTD2020

Identification of elastic properties of human patellae using micro-finite element analysis

Dominique Pioletti, Alexandre Terrier, Adeliya Latypova

Current homogenized finite element (hFE) models of the patella lack a validated material law and mostly overlook trabecular anisotropy. The objective of this study was to identify the elastic constants of patellar trabecular bone. Using mu CT scans of 20 f ...

Elsevier2016

Translation of biomechanical concepts in bone tissue engineering: from animal study to revision knee arthroplasty

Dominique Pioletti, Alexandre Terrier, Brigitte Jolles-Haeberli, Alireza Roshan Ghias

Bone defects in revision knee arthroplasty (RKA) are often located in load-bearing regions. The goal of this study was to determine if a physiologic load could be used as an in situ osteogenic signal to the scaffolds filling the bone defects. In order to a ...

Taylor & Francis2014

Comparison of the ALPS and PHILOS plating systems in proximal humeral fracture fixation - a retrospective study

Alexandre Terrier, Frédéric Vauclair, Antoine Dewarrat

BackgroundOpen reduction and plate osteosynthesis are considered as a successful technique for the treatment of proximal humerus fracture (PHF) despite high complication rates. The objective of our study was to review the clinical outcome and complications ...

BMC2023

3D strain map of axially loaded mouse tibia: a numerical analysis validated by experimental measurements

Dominique Pioletti, Alexandre Terrier, Vincent Stadelmann, Francesco Merlini

A combined experimental/numerical study was performed to calculate the 3D octahedral shear strain map in a mouse tibia loaded axially. This study is motivated by the fact that the bone remodelling analysis, in this in vivo mouse model should be performed a ...

2009