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Heinrich Hofmann

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Publications associées (116)

Page 4 sur 6

Pièce en céramique pigmentée

Heinrich Hofmann, Alke Fink

NOVELTY - The component partially or wholly comprises pigmented ceramic. The pigment comprises nanoparticles of metal of group IB in periodic table, alkaline metals or their alloy, coated with a layer of silica such as crystalline silica. The crystalline s ...

2006

Conductive SU8 Photoresist for Microfabrication

Philippe Renaud, Heinrich Hofmann, Arnaud Bertsch, Sébastien Jiguet

A conductive composite photoresist has been developed for the direct photopatterning of electrodes. It is based on a dispersion of silver nanoparticles in SU8, a non-conductive, negative-tone photoresist. Manufactured structures have an electrical conducti ...

2005

Characterization of PEI-coated superparamagnetic iron oxide nanoparticles for transfection: Size distribution, colloidal properties and DNA interaction

Heinrich Hofmann, Alke Fink, Benedikt Steitz

Superparamagnetic iron oxide nanoparticles (SPIONs) were coated with polyethylenimine. Here, we briefly describe the synthesis as well as DNA:PEI:SPION complexes and the characterization of the compounds according to their particle size, zeta-potential, mo ...

2007

Controlling structural and magnetic properties of IONPs by aqueous synthesis for improved hyperthermia

Heinrich Hofmann, Alla Arakcheeva, Marijana Mionic Ebersold, Débora Bonvin

Iron oxide nanoparticles (IONPs) were synthesized by a novel aqueous synthesis route which combines co-precipitation (CP) and hydrothermal (HT) treatment, termed CP + HT, and compared with IONPs obtained by the standard CP method. Properties of both types ...

2017

In-situ electrical addressing of one-dimensional gold nanoparticle assemblies

Heinrich Hofmann, Frédéric Juillerat

Substrates with 1-dimensional nanosize grooves were prepared using extreme-ultraviolet interference lithography (EUV-IL), wherein gold nanoparticles were self-assembled to form 1-dimensional structures. To measure the electrical properties of gold nanopart ...

2008

Superparamagnetic iron oxide nanoparticles (SPIONs): from synthesis to in vivo studies - A summary of the synthesis, characterization, in vitro and in vivo investigations of SPIONs with particular focus on surface and colloidal properties

Heinrich Hofmann, Alke Fink

In this work, we present a short summary of the synthesis and characterization of superparamagnetic iron oxide nanoparticles and their behavior in vitro and in vivo. Therefore, we have used various characterization techniques to deduce the physical particl ...

2007

Protein Corona: Impact of Lymph Versus Blood in a Complex In Vitro Environment

Heinrich Hofmann, Duncan Thomas Lindsay Alexander, Marc Moniatte, Marijana Mionic Ebersold, Débora Bonvin, Ulrich Aschauer, Diego Chiappe

In biological environments, the surface of nanoparticles (NPs) are modified by protein corona (PC) that determines their biological behavior. Unfortunately, in vitro tests still give different PC than in vivo tests causing in vitro-in vivo discrepancy; hen ...

Wiley-Blackwell2017

Evaluation of uptake and transport of ultrasmall superparamagnetic iron oxide nanoparticles by human brain-derived endothelial cells

Heinrich Hofmann

Aim: Ultrasmall superparamagnetic iron oxide nanoparticles (USPIO-NPs) are under development for imaging and drug delivery; however, their interaction with human blood brain barrier models is not known. Materials & Methods: The uptake, reactive oxygen spec ...

2012

Transfer studies of polystyrene nanoparticles in the ex vivo human placenta perfusion model: key sources of artifacts

Heinrich Hofmann, Lionel André Maurizi

Nanotechnology is a rapidly expanding and highly promising new technology with many different fields of application. Consequently, the investigation of engineered nanoparticles in biological systems is steadily increasing. Questions about the safety of suc ...

Elsevier2015

MULTIFUNCTIONALIZED SPIONs FOR NUCLEAR TARGETING: CELL UPTAKE AND GENE EXPRESSION

Heinrich Hofmann, Alke Fink

Superparamagnetic iron oxide nanoparticles (SPIONs) are used in many biological applications, which necessitate intracellular targeting. Here, we investigate intracellular localization and gene expression in HeLa cells after treatment with functionalized S ...

World Scientific Publ Co Pte Ltd2014

Superparamagnetic Nanoparticles as a Powerful Systems Biology. Characterization Tool in the Physiological Context

Jeffrey Alan Hubbell, Heinrich Hofmann, Alke Fink, Marc Moniatte, Benedikt Steitz, Andrija Finka

Recently, functionalized superparamagnetic iron oxide nanoparticles (SPIONs) have been utilized for protein separation and therapeutic delivery of DNA and drugs. The development of new methods and tools for the targeting and identification of specific biom ...

Wiley-Blackwell2008

Fabrication of large-area ordered arrays of nanoparticles on patterned substrates

Heinrich Hofmann, Paul Bowen, Frédéric Juillerat

Many potential applications in nanotechnology require virtually defect-free arrays of nanometre-scale particles over large areas. Guided self-assembly of colloidal particles on patterned templates has been shown to produce ordered arrays of colloidal parti ...

2005

Formation and Drying of Colloidal Crystals Using Nanosized Silica Particles

Heinrich Hofmann, Paul Bowen, Frédéric Juillerat

Much interest has been generated in the fabrication of colloidal crystals from suspensions because of the promise of photonic band gap applications. However, since the case of small, nonsedimenting colloidal particles indeed remains rather rarely treated, ...

2006

Cathode-supported micro-tubular SOFCs based on Nd1.95NiO4 + δ: Fabrication and characterisation of dip-coated electrolyte layers

Heinrich Hofmann, Jan Van Herle, Paul Bowen, Josef Andreas Schuler, Ulrich Aschauer, Henning Lübbe

Fabrication conditions to obtain dense electrolyte double layers on a porous micro-tubular cathode substrate were investigated. Porous tubes of a nickelate material, Nd1.95NiO4 + δ, were fabricated by cold-isostatic pressing (CIP) and sintering. Thin ﬁlms ...

2009

Critical raw materials: A perspective from the materials science community

Heinrich Hofmann

Functional materials are crucial to meet today's societal challenges and needs, such as the transition towards low carbon energy production to reduce climate change, renewable energies and green economy, clean mobility and improved communication. In order ...

ELSEVIER SCIENCE BV2018

Syntheses of cross-linked polymeric superparamagnetic beads with tunable properties

Heinrich Hofmann, Lionel André Maurizi, Usawadee Sakulkhu, Vanessa Mai Dao

A novel, rapid and reproducible method to synthesize functionalized magnetic beads with an original shape is presented. By coating Fe2O3 nanoparticles with PVA, it was possible to tune the size, the number of iron oxide nanoparticles encapsulated and the o ...

RSC Publishing2014

Hydrophobization of silver nanoparticles through surface-initiated atom transfer radical polymerization

Heinrich Hofmann, Frank Nüesch, Jose Enrico Quijano Quinsaat

This work describes the synthesis of poly(methyl methacrylate) (PMMA)-coated Ag@SiO2 core-shell particles by conducting a Surface-Initiated Atom Transfer Radical Polymerization (SI-ATRP). Silver nanoparticles (AgNPs) were first prepared by the polyol synth ...

RSC Publishing2016

Methodology description for detection of cellular uptake of PVA coated superparamagnetic iron oxide nanoparticles (SPION) in synovial cells of sheep

Heinrich Hofmann, Alke Fink, Mathieu Chastellain

The detection of superparamagnetic iron oxide nanoparticles (SPION) in synoviocytes is reported. Synoviocytes were incubated for 2, 12, 24 and 48 h with 1.5 mg/ml of PVA coated SPION under the influence of magnets (12 h). Particles were well tolerated by t ...

2005

Development of biocompatible functionalized superparamagnetic iron oxide nanoparticles for human cancer cell uptake and intracellular delivery

Heinrich Hofmann, Alessio Ferrari, Alke Fink, Mathieu Chastellain

2005

Particle Size Distribution Measurements of Manganese-Doped ZnS Nanoparticles

Heinrich Hofmann, Alke Fink

We performed particle size and particle size distribution measurements for L-cysteine-stabilized ZnS/Mn nanoparticles in the size region below 10 nm. For this we applied transmission electron microscopy (TEM), analytical ultracentrifugation (AUC), dynamic ...

2009