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Heinrich Hofmann

Cette personne a quitté l’EPFL

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Publications associées (116)

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Dielectric properties of silver nanoparticles coated with silica shells of different thicknesses

Heinrich Hofmann, Jose Enrico Quijano Quinsaat

Core/shell nanoparticles having metallic silver nanoparticle cores of similar to 38 nm in diameter and silica shells of different thicknesses ranging from similar to 3.6-20 nm were prepared. For the silica coating, a slightly modified Stober method was use ...

RSC Publishing2013

A fast and reproducible method to quantify magnetic nanoparticle biodistribution

Heinrich Hofmann, Lionel André Maurizi, Usawadee Sakulkhu

The quantification of nanoparticles, particularly superparamagnetic iron oxide nanoparticles (SPIONs), both in vitro and in vivo has become highly important in recent years. Some methods, such as induced coupled plasma (ICP) spectroscopy and UV-visible che ...

Royal Society of Chemistry2014

Transparent and Robust Silica Coatings with Dual Range Porosity for Enzyme-Based Optical Biosensing

Heinrich Hofmann, Bernard Wenger, Oswaldo Anguiano

Hierarchically porous transparent silica coatings combine large specific surface area with enhanced pore accessibility for optical biosensing. This paper describes a versatile approach to fabricate optically transparent silica coatings with multiscale poro ...

Wiley-Blackwell2017

Beyond Unpredictability: The Importance of Reproducibility in Understanding the Protein Corona of Nanoparticles

Heinrich Hofmann, Diego Chiappe, Sandra Caroline Galmarini, Lionel André Maurizi, Nadia Rachel Von Moos

While it is well established that the surface of a nanoparticle plays a pivotal role for the protein corona, the vast number of proteins present in biological media render general conclusions about affinities between nanoparticle surfaces and proteins nont ...

AMER CHEMICAL SOC2018

Factors influencing safety and efficacy of intravenous iron-carbohydrate nanomedicines: From production to clinical practice

Heinrich Hofmann

Iron deficiency is an important subclinical disease affecting over one billion people worldwide. A growing body of clinical records supports the use of intravenous iron-carbohydrate complexes for patients where iron replenishment is necessary and oral iron ...

2020

Magnetic nanoparticle-induced hyperthermia with appropriate payloads: Paul Ehrlich's "magic (nano)bullet" for cancer theranostics?

Heinrich Hofmann

Effective multimodal cancer management requires the optimal integration of diagnostic and therapeutic modalities. Radiation therapy, chemotherapy and immunotherapy, alone or in combination, are integral parts of various cancer treatment protocols. Hyperthe ...

Elsevier2016

Fabrication and Characterisation of Cathode Support-tubes for Micro-tubular SOFC Application

Jan Van Herle, Heinrich Hofmann, Paul Bowen, Stefan Diethelm, John Espen Rossen

Tubes of diameter

2009

Superparamagnetic iron oxide binding and uptake as imaged by magnetic resonance is mediated by the integrin receptor Mac-1 (CD11b/CD18): Implications on imaging of atherosclerotic plaques

Heinrich Hofmann, Alke Fink, Benedikt Steitz

Introduction: Superparamagnetic iron oxide nanoparticles (SPIONs) have been successfully used for magnetic resonance imaging (MRI) of atherosclerotic plaques. Endocytosis into monocytes/macrophages has been proposed as the mechanism for SPION uptake, but a ...

Elsevier2007

Amino-polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles are Suitable for Monitoring of Human Mesenchymal Stromal Cells In Vivo

Heinrich Hofmann, Lionel André Maurizi

Mesenchymal stromal cells (MSCs) are promising candidates in regenerative cell-therapies. However, optimizing their number and route of delivery remains a critical issue, which can be addressed by monitoring the MSCs' bio-distribution in vivo using super-p ...

Wiley-Blackwell2014

Fixed bed reactor for solid phase surface derivatization of superparamagnetic nanoparticles

Heinrich Hofmann, Alke Fink, Benedikt Steitz, Andrija Finka

The functionalization of nanoparticles is conditio sine qua non in studies of specific interaction with a biological target. Often, their biological functionality is achieved by covalent binding of bioactive molecules on a preexisting single surface coatin ...

2007

Improved dynamic response assessment for intra-articular injected iron oxide nanoparticles

Heinrich Hofmann, Alke Fink

The emerging importance of nanoparticle technology, including iron oxide nanoparticles for monitoring development, progression, and treatment of inflammatory diseases such as arthritis, drives development of imaging techniques. Studies require an imaging p ...

Wiley-Blackwell2012

Engineered nanomaterials: toward effective safety management in research laboratories

Heinrich Hofmann, Thierry Meyer, Alke Fink, Amela Groso

Background: It is still unknown which types of nanomaterials and associated doses represent an actual danger to humans and environment. Meanwhile, there is consensus on applying the precautionary principle to these novel materials until more information is ...

BioMed Central2016

Precipitation of Nanostructured Copper Oxalate: Substructure and Growth Mechanism

Heinrich Hofmann, Paul Bowen, Jacques Lemaître, Lucica Soare

The possibility of controlling materials properties by tailoring their substructure at the nanometer scale is a current topic of great interest. To do so, a fundamental understanding of the growth mechanism is of key importance and an analytical challenge ...

2006

Drug loading of porous coating

Heinrich Hofmann, Laurent-Dominique Piveteau

Porous coating for the controlled release of drugs, said coating comprising a porous structure with pores adapted to act as reservoirs or as passages for a drug, in such a way that said drug can move from the external environment to/from or through said po ...

2006

Analysis of Quantized Electrical Characteristics of Microscale TiO2 Ink-Jet Printed Memristor

Heinrich Hofmann, Marijana Mionic Ebersold

We demonstrate the ink-jet printed fabrication technique for TiO2-based memristor, followed by detailed analysis of electrical characteristics and development of a new model that considers observed phenomena of quantized conductance steps. The existence of ...

Institute of Electrical and Electronics Engineers2015

SU-8 nanocomposite coatings with improved tribological performance for MEMS

Philippe Renaud, Heinrich Hofmann, Arnaud Bertsch, Stefano Mischler, Sébastien Jiguet

The increasing interests in micro-electro-mechanical systems (MEMS) has raised the requirement for photoresist materials with improved friction and wear properties for mechanically loaded 3D shaped microstructures. In this work, SU8 photoresist layers rein ...

2006

Superparamagnetic iron oxide nanoparticle coupled tissue soldering

Heinrich Hofmann, Alke Fink, Benedikt Steitz

The invention relates to superparamagnetic iron oxide nanoparticles for use in sutureless thermal mediated tissue fusion. The nanoparticles are dispersed in a biocompatible solder material and heated by application of an alternating electromagnetic field. ...

2007

Effects of PVA coated nanoparticles on human immune cells

Heinrich Hofmann, Lionel André Maurizi

Nanotechnology provides new opportunities in human medicine, mainly for diagnostic and therapeutic purposes. The autoimmune disease rheumatoid arthritis (RA) is often diagnosed after irreversible joint structural damage has occurred. There is an urgent nee ...

Dove Medical Press Ltd2015

Nanostructured Ceramic Coatings for Drug Delivery

Heinrich Hofmann, Laurent-Dominique Piveteau

Drug eluting stents (DES) have been successfully implemented in clinical practice in the treatment against coronary artery disease. Compared to the implantation of bare metal stents, restenosis rates decreased significantly after stenting of DES into coron ...

Materials Research Society, 506 Keystone Drive, Warrendale, Pa 15086-7573 Usa2009

Study and characterization of soft magnetic materials for beam intensity monitors at CERN

Heinrich Hofmann, Silvia Aguilera Murciano

At CERN, the circulating beam current measurement is provided by two types of transformers, the DC Current Transformer (DCCT) and the Fast Beam Current Transformer (FBCT). Each transformer is built based on toroidal cores made from a magnetic material. Dep ...

Iop Publishing Ltd2017