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Kathryn Hess Bellwald

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Publications associées (55)

Two-Tier Mapper, an unbiased topology-based clustering method for enhanced global gene expression analysis

Kathryn Hess Bellwald, Cathrin Brisken, Jacques Rougemont, Rachel Marcone

Motivation: Unbiased clustering methods are needed to analyze growing numbers of complex data sets. Currently available clustering methods often depend on parameters that are set by the user, they lack stability, and are not applicable to small data sets. ...

2019

Topological Analysis Enables Prediction Of Functional And Social Outcomes In Early Psychosis

Kathryn Hess Bellwald, Mehdi Gholam, Martina Scolamiero, Kim Do

OXFORD UNIV PRESS2019

Topological exploration of artificial neuronal network dynamics

Kathryn Hess Bellwald, Gard Spreemann

One of the paramount challenges in neuroscience is to understand the dynamics of individual neurons and how they give rise to network dynamics when interconnected. Historically, researchers have resorted to graph theory, statistics, and statistical mechani ...

2019

The unfolding argument: Why IIT and other causal structure theories cannot explain consciousness

Kathryn Hess Bellwald, Michael Herzog, Adrien Christophe Doerig, Aaron Schurger

How can we explain consciousness? This question has become a vibrant topic of neuroscience research in recent decades. A large body of empirical results has been accumulated, and many theories have been proposed. Certain theories suggest that consciousness ...

2019

The Homotopy Theory Of Coalgebras Over Simplicial Comonads

Kathryn Hess Bellwald, Magdalena Kedziorek

We apply the Acyclicity Theorem of Hess, Kedziorek, Riehl, and Shipley (recently corrected by Garner, Kedziorek, and Riehl) to establishing the existence of model category structure on categories of coalgebras over comonads arising from simplicial adjuncti ...

INT PRESS BOSTON, INC2019

Configuration Spaces Of Products

Kathryn Hess Bellwald

We show that the configuration spaces of a product of parallelizable manifolds may be recovered from those of the factors as the Boardman-Vogt tensor product of right modules over the operads of little cubes of the appropriate dimension. We also discuss an ...

2019

Objective Morphological Classification of Neocortical Pyramidal Cells

Kathryn Hess Bellwald, Henry Markram, Rodrigo de Campos Perin, Srikanth Ramaswamy, Julie Meystre, Yun Wang, Ying Shi, Marwan Muhammad Ahmed Abdellah, Lida Kanari

A consensus on the number of morphologically different types of pyramidal cells (PCs) in the neocortex has not yet been reached, despite over a century of anatomical studies, due to the lack of agreement on the subjective classifications of neuron types, w ...

Oxford University Press (OUP)2019

A Topological Representation of Branching Neuronal Morphologies

Kathryn Hess Bellwald, Henry Markram, Ran Levi, Martina Scolamiero

2018

High-Throughput Screening Approach for Nanoporous Materials Genome Using Topological Data Analysis: Application to Zeolites

Kathryn Hess Bellwald, Seyedmohamad Moosavi, Berend Smit, Pawel Tadeusz Dlotko, Yongjin Lee, Senja Dominique Barthel

2018

Homotopic Hopf-Galois extensions revisited

Kathryn Hess Bellwald

2018

Homotopical Morita theory for corings

Kathryn Hess Bellwald

2018

Generating and identifying functional subnetworks within structural networks

Kathryn Hess Bellwald, Henry Markram, Michael Reimann, Ran Levi, Max Christian Nolte

In one aspect, a method includes generating a functional subgraph of a network from a structural graph of the network. The structural graph comprises a set of vertices and structural connections between the vertices. Generating the functional subgraph incl ...

2018

Quantifying similarity of pore-geometry in nanoporous materials

Kathryn Hess Bellwald, Berend Smit, Pawel Tadeusz Dlotko, Yongjin Lee, Senja Dominique Barthel

In most applications of nanoporous materials the pore structure is as important as the chemical composition as a determinant of performance. For example, one can alter performance in applications like carbon capture or methane storage by orders of magnitud ...

Nature Publishing Group2017

A necessary and sufficient condition for induced model structures

Kathryn Hess Bellwald, Magdalena Kedziorek

A common technique for producing a new model category structure is to lift the fibrations and weak equivalences of an existing model structure along a right adjoint. Formally dual but technically much harder is to lift the cofibrations and weak equivalence ...

Wiley2017

Cliques of Neurons Bound into Cavities Provide a Missing Link between Structure and Function

Kathryn Hess Bellwald, Henry Markram, Rodrigo de Campos Perin, Michael Reimann, Giuseppe Chindemi, Ran Levi, Max Christian Nolte, Pawel Tadeusz Dlotko, Katharine Felicity Turner, Martina Scolamiero

The lack of a formal link between neural network structure and its emergent function has hampered our understanding of how the brain processes information. We have now come closer to describing such a link by taking the direction of synaptic transmission i ...

Frontiers Media Sa2017

Topological Analyses Of Metabolomic Data To Identify Markers Of Early Psychosis And Disease Biotypes

Kathryn Hess Bellwald, Martina Scolamiero, Kim Do

Oxford Univ Press2017

Waldhausen K-theory of spaces via comodules

Kathryn Hess Bellwald

Let X be a simplicial set. We construct a novel adjunction be- tween the categories RX of retractive spaces over X and ComodX+ of X+- comodules, then apply recent work on left-induced model category structures [5], [16] to establish the existence of a left ...

Academic Press Inc Elsevier Science2016

The Hochschild complex of a twisting cochain

Kathryn Hess Bellwald

Given any twisting cochain t:C→A , where C is a connected, coaugmented chain coalgebra and A is an augmented chain algebra over an arbitrary commutative ring R, we construct a twisted extension of chain complexes Full-size image (1 K) of which both the wel ...

Elsevier2016

Left-induced model structures and diagram categories

Kathryn Hess Bellwald, Varvara Karpova, Magdalena Kedziorek

We prove existence results à la Jeff Smith for left-induced model category structures, of which the injective model structure on a diagram category is an important example. We further develop the notions of fibrant generation and Postnikov presentation fro ...

2015

Progesterone and Overlooked Endocrine Pathways in Breast Cancer Pathogenesis

Kathryn Hess Bellwald, Cathrin Brisken, Rachel Marcone

Worldwide, breast cancer incidence has been increasing for decades. Exposure to reproductive hormones, as occurs with recurrent menstrual cycles, affects breast cancer risk, and can promote disease progression. Exogenous hormones and endocrine disruptors h ...

2015

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