Protocol for live imaging of intracellular nanoscale structures using atomic force microscopy with nanoneedle probes

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Atomic force microscopy (AFM) is the only technique that allows label-free imaging of nanoscale biomolecular dynamics, playing a crucial role in solving biological questions that cannot be addressed by other major bioimaging tools (fluorescence or electron ...

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Over the last decade, nanoneedle-based systems have demonstrated to be extremely useful in cell biology. They can be used as nanotools for drug delivery, biosensing or biomolecular recognition inside cells; or they can be employed to select and sort in par ...

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Protocol for live imaging of intracellular nanoscale structures using atomic force microscopy with nanoneedle probes

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