Publication

Method and system for determining intracellular mediators' activity

Philippe Renaud, Horst Arthur Vogel, Thamani Dahoun, Margaux Catherine Marie Duchamp, Marc Brugarolas Campillos
2022
Patents

Abstract

A method for determining the presence of a molecule coupled to the cytoplasmic side of a cellular membrane is disclosed. The method is implemented in a microfluidic setting and is particularly suitable for determining the presence and/or the activity of a G protein or an arrestin protein in a cell.

Official source

https://infoscience.epfl.ch/entities/publication/8619c919-953d-43eb-8a72-0d1e682b6213

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Method and system for determining intracellular mediators' activity

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Computational drug development for membrane protein targets

From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

Investigating the intra-molecular and inter-molecular effects of post-translational modifications on intrinsically disordered protein regions and structured protein regions