Lipid Receptor S1P(1) Activation Scheme Concluded from Microsecond All-Atom Molecular Dynamics Simulations

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Lipid Receptor S1P(1) Activation Scheme Concluded from Microsecond All-Atom Molecular Dynamics Simulations

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From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

Computational drug development for membrane protein targets

Investigating the intra-molecular and inter-molecular effects of post-translational modifications on intrinsically disordered protein regions and structured protein regions

Structural heterogeneity of the ion and lipid channel TMEM16F

Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development

Antibodies expand the scope of angiotensin receptor pharmacology

Characterization of the gut-bone marrow axis through bile acid signaling

Predicting protein interactions using geometric deep learning on protein surfaces

Variants of the gain domain of adhesion g protein-coupled receptors

Rules and mechanisms governing G protein coupling selectivity of GPCRs

Unlocking Hidden Potential: Exploring the Complexities of Signaling in Immune Cell Activation to Optimize CAR Therapy

Exploring the interplay of molecular pattern and valency for selective interactions at the bio-interface

Development of a novel Chimeric Antigen Receptor (CAR) for its use in Natural Killer (NK) cells for cancer treatment and beyond

Microfluidic device combining hydrodynamic and dielectrophoretic trapping for the controlled contact between single micro-sized objects and application to adhesion assays

A Geometric Transformer for Structural Biology: Development and Applications of the Protein Structure Transformer

Screening for drivers of SARS-CoV-2 uptake

Quantifying single-cell diacylglycerol signaling kinetics after uncaging

Protein target highlights in CASP15: Analysis of models by structure providers

De novo designed proteins: a study in engineering novel folds and functions

Computer-implemented design of peptide:receptor signaling complexes for enhanced chemotaxis