Pierre Vogel

Mission BIOGRAPHYRESEARCH TOPICS (more than 400 publications in referred journals) Asymmetric Synthesis of Natural Products and Analogs of Biological Interest (anti-cancer, antiviral agents, antibiotics). Actual targets: Spongistatins (anti-cancer), Aptotolidin (anti-cancer), oxopolyene RK-397 (antibiotic), Ryfamycins (antibiotics, antifungals, Erythronolides (antibiotics).Glycomimetics as New Tools for Biology and Medicine (glycomics, cell/cell communication, cell/pathogen communication: glycosidase and glycosyltransferase inhibitors, non-hydrolysable sugar epitopes). New inhibitors of α-mannosidases and α-glucosidases as potential anti-cancer and anti-HIV agents. Artificial vaccines against cancer, synthesis of C-linked disaccharides analogs of the T-epitopes.New Scaffolds for Biomolecules, for New Materials (polyfunctional systems for combinatorial chemistry, multicomponent synthesis).New Organic Chemistry of Sulfur Dioxide (new C-C bond forming reactions, synthesis of polyketides and polypropionates, new reagents, new organic catalysts for hole-catalysed reactions). BIOGRAPHIE Professional positions: P. Vogel was born in Cully (Switzerland) Oct. 23, 1944. In 1969, he did his Ph.D under supervision of Prof. H. Prinzbach at the Institute of Organic Chemistry, University of Lausanne. He spent two years at Yale University, New Haven, Connecticut, USA with Prof. Martin Saunders, Prof. J. A. Berson, K. A. Wiberg and P.v.R. Schleyer (Princeton Universtiy). He worked then as a Research chemist at Syntex S.A., in Mexico with Prof. P.Crabbé before the return to the University of Lausanne in 1973. As of 1977 he became Professor of organic chemistry at the University of Lausanne. In 1991 he was Vice-Chairman of the Institute of organic Chemistry, University of Lausanne until 2001. He was also part-time grad.school teacher at the Universities of Rouen and Caen from 1991 to 1993 and Part-time professor at Ecole Polytechnique de Palaiseau from 1993-2000. Since 2001 he is Professor of organic chemistry at the EPFL. Degrees and distincions 1969 Ph.D, University of Lausanne 1976 Swiss Chemical Society Award, Werner Medal 1984-1989 IOCD adviser 1988-1989 Associate Professor of Organic Chemistry at Ecole Normale Supérieure, Paris 1989-2000 Member of the Swiss National Council of Research 1991-1992 Associate Professor of Organic Chemistry, University of Paris VI 1992 Pacific Coast Lecturer (USA) 1992-1993 Associate Professor at the Université de Montpellier, France 1993 Associate Professor, Université Paris Sud, Orsay 1994 (spring) Associate Professor, ESPCI, Paris 1997 President of the european COST D2 management committee 2002-2003 Novartis Lecturer 2004-2005 Boehringer Ingelheim Distinguished LecturerSenior co-workers Dr. Sandrine Gerber-LemaireDr. Mariz TurksDr. Robert Lysek Teaching & PhD Past EPFL PhD Students Hervé Mosimann, Marc-Etienne Schwenter, Patrick Gerber, Sophie Megevand, Raynald Demange, Kai Torsten Meilert, Frédéric Carrel, Florence Popowycz, Laure Bouchez, Xiaogen Huang, Loay Awad, Eliazar Rodriguez Garcia, Peter Steunenberg, Dean Markovic, Maris Turks, Cotinica Craita, Freddy Fonquerne, Srinivas Reddy Dubbaka, Sylvain Favre, Claudia Bello, Chandra Mouleeswara Rao Volla, Sylvain Claude Laclef, Annabelle Gillig, Christopher Flowers, Claudia Jana Exner, Maria Kolympadi