Publications by Hatice Altug | EPFL Graph Search

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We propose a disruptive point-of-care (PoC) imaging platform based on lens-free interference phase-contrast imaging for rapid detection of biomarker such as for sepsis and potentially other diseases (e.g. cancer). It enables simultaneous analysis of potent ...

Tailoring nanoscale light concentration and electromagnetic near-field enhancement over a broad spectral range is crucial for many photonics applications such as infrared spectroscopy, photodetection, and light harvesting. So far, broadband light enhanceme ...

A method of investigating a sample (1) having an absorption within an infrared spectral range of interest, comprises the steps of creating measuring light (2) with a light source device (10), wherein the measuring light (2) includes wavelengths covering th ...

Mid-infrared spectrum is powerful for biosensing application, as it encompasses the molecular vibrations that uniquely identify the biochemicals. Here, we will present our contributions using metal, graphene and dielectric based Mid-IR nanophotonics. ...

Metasurfaces have emerged as a breakthrough platform for manipulating light at the nanoscale and enabling on-demand optical functionalities for next-generation biosensing, imaging, and light-generating photonic devices. However, translating this technology ...

The implementation of multiplexed point-of-care biosensors is a top priority to address the current epidemic problems originated by widespread pathogenic infections, like those caused by viruses or bacteria. A rapid and accurate detection, identification, ...

Existing clinical methods for bacteria detection lack speed, sensitivity, and, importantly, point-of-care (PoC) applicability. Thus, finding ways to push the sensitivity of clinical PoC biosensing technologies is crucial. Here we report a portable PoC devi ...

This Review discusses the progresses in label-free nanophotonic biosensors based on photonic or dielectric surfaces and metasurfaces and highlights the challenges and benefits of their applications in the fields of public health, well-being and biosafety. ...

We introduce an infrared metasurface sensor based on plasmonic surface-enhanced infrared absorption spectroscopy combined with immunoassay, which detects alpha-synuclein, an early structural biomarker protein for neurodegenerative diseases with clinical sp ...

The precision and versatility of CRISPR-based techniques, combined with the advantages of nucleic acid-based nanotechnology, hold great promise in transforming the landscape of molecular diagnostics. While significant progress has been made, current CRISPR ...

Mid-infrared absorption spectroscopy is a powerful tool for optically probing the molecular structure of biological samples. However, using conventional approaches, IR measurements on small quantities of molecules are extremely challenging due to sensitivi ...

Many photonic and electronic molecular properties, as well as chemical and biochemical reactivities are controlled by fast intramolecular vibrational energy redistribution (IVR). This fundamental ultrafast process limits coherence time in applications from ...

Low-loss nanostructured dielectric metasurfaces have emerged as a breakthrough platform for ultrathin optics and cutting-edge photonic applications, including beam shaping, focusing, and holography. However, the static nature of their constituent materials ...

Infrared spectroscopy resolves the structure of molecules by detecting their characteristic vibrational fingerprints. Subwavelength light confinement and nanophotonic enhancement have extended the scope of this technique for monolayer studies. However, cur ...

Chirality (C) is a fundamental property of objects, in terms of symmetry. It is extremely important to sense and distinguish chiral molecules in the fields of biochemistry, science, and medicine. Vibrational circular dichroism (VCD) spectroscopy, obtained ...

Based on the ASHRAE Standard 140-2014, this study takes the simulation results of DeST and other simulation software to comprehensively test the accuracy and validity of DeST in calculating building thermal loads and space cooling and heating equipment per ...

Plasmonic nanoantennas offer new applications in mid-infrared (mid-IR) absorption spectroscopy with ultrasensitive detection of structural signatures of biomolecules, such as proteins, due to their strong resonant near-fields. The amide I fingerprint of a ...

Nanoplasmonic structures can tightly confine light onto a material's surface to probe biomolecular interactions not easily accessed by other sensing techniques. New and exciting developments in nanofabrication processes, nano-optical trapping, graphene dev ...

Advances in organoid models, as ex vivo mini-organs, and the development of screening imaging technologies have continuously driven each other forward. A complete understanding of organoids requires detailed insights into the intertwined intraorganoid and ...

Insights into the fascinating molecular world of biological processes are crucial for understanding diseases, developing diagnostics, and effective therapeutics. These processes are complex as they involve interactions between four major classes of biomole ...

Hatice Altug

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Label-free, scalable and point-of-care imaging platform for rapid analysis of biomarker

Self-Similar Multiresonant Nanoantenna Arrays for Sensing from Near- to Mid-Infrared

Method and spectrometer apparatus for investigating an infrared absorption of a sample

Plasmonic and Dielectric Metasurfaces for Molecular Specific Mid-IR Biosensors

Wafer‐Scale Functional Metasurfaces for Mid‐Infrared Photonics and Biosensing

Towards a point-of-care nanoplasmonic biosensor for rapid and multiplexed detection of pathogenic infections

Label-free Bacteria Quantification in Blood Plasma by a Bioprinted Microarray Based Interferometric Point-of-Care Device

Advances and applications of nanophotonic biosensors

Deep learning augmented nanoplasmonic infrared sensor for structural protein biomarker-based detection of neurodegenerative diseases

Challenges and perspectives of CRISPR-based technology for diagnostic applications

Engineering mid-infrared nanoantennas for surface enhanced infrared absorption spectroscopy

Antenna-coupled infrared nanospectroscopy of intramolecular vibrational interaction

All-Dielectric Programmable Huygens' Metasurfaces

Angle-multiplexed all-dielectric metasurfaces for broadband molecular fingerprint retrieval

Dielectric Tetramer Nanoresonators Supporting Strong Superchiral Fields for Vibrational Circular Dichroism Spectroscopy

Comparison and Verification of Simulation Results of DeST Based on ASHRAE-140 Standard

Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection

Performance metrics and enabling technologies for nanoplasmonic biosensors

Spatiotemporal Interrogation of Single Spheroids Using Multiplexed Nanoplasmonic-fluorescence Imaging

Infrared Metasurface Augmented by Deep Learning for Monitoring Dynamics between All Major Classes of Biomolecules