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Hatice Altug

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Related publications (119)

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Antenna-coupled infrared nanospectroscopy of intramolecular vibrational interaction

Hatice Altug, Aurélian Michel John-Herpin

Many photonic and electronic molecular properties, as well as chemical and biochemical reactivities are controlled by fast intramolecular vibrational energy redistribution (IVR). This fundamental ultrafast process limits coherence time in applications from ...

National Academy of Sciences2023

Nanoparticle-Enhanced Plasmonic Biosensor for Digital Biomarker Detection in a Microarray

Hatice Altug, Filiz Yesilköy, Alexander Belushkin

Nanoplasmonic devices have become a paradigm for biomolecular detection enabled by enhanced light–matter interactions in the fields from biological and pharmaceutical research to medical diagnostics and global health. In this work, we present a bright-fiel ...

2018

Integrated angular tracking and plasmonic membrane surfaces for a point of a care refractive index sensor

Hatice Altug

We present an optical system which integrates a plasmonic sensing surface and an angular tracking system to enable a compact refractive index measurement. A refractive index change at the surface of the sensing membrane causes a change in the angle at whic ...

Spie-Int Soc Optical Engineering2016

Plasmonic nanohole arrays on Si-Ge heterostructures: An approach for integrated biosensors

Hatice Altug, Liza Carol Andrea Dunbar, Dordaneh Etezadi

Nanohole array surface plasmon resonance (SPR) sensors offer a promising platform for high-throughput label-free biosensing. Integrating nanohole arrays with group-IV semiconductor photodetectors could enable low-cost and disposable biosensors compatible t ...

Spie-Int Soc Optical Engineering2016

All-Dielectric Programmable Huygens' Metasurfaces

Hatice Altug, Andreas Tittl, Aleksandrs Leitis

Low-loss nanostructured dielectric metasurfaces have emerged as a breakthrough platform for ultrathin optics and cutting-edge photonic applications, including beam shaping, focusing, and holography. However, the static nature of their constituent materials ...

2020

Angle-multiplexed all-dielectric metasurfaces for broadband molecular fingerprint retrieval

Hatice Altug, Andreas Tittl, Aleksandrs Leitis

Infrared spectroscopy resolves the structure of molecules by detecting their characteristic vibrational fingerprints. Subwavelength light confinement and nanophotonic enhancement have extended the scope of this technique for monolayer studies. However, cur ...

2019

Dielectric Tetramer Nanoresonators Supporting Strong Superchiral Fields for Vibrational Circular Dichroism Spectroscopy

Longfang Ye, Hatice Altug, Yasaman Jahani, Felix Ulrich Brikh, Ming-Lun Tseng

Chirality (C) is a fundamental property of objects, in terms of symmetry. It is extremely important to sense and distinguish chiral molecules in the fields of biochemistry, science, and medicine. Vibrational circular dichroism (VCD) spectroscopy, obtained ...

Amer Chemical Soc2023

Comparison and Verification of Simulation Results of DeST Based on ASHRAE-140 Standard

Hatice Altug, Andreas Tittl, Aleksandrs Leitis

Based on the ASHRAE Standard 140-2014, this study takes the simulation results of DeST and other simulation software to comprehensively test the accuracy and validity of DeST in calculating building thermal loads and space cooling and heating equipment per ...

IEEE2021

Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection

Hilal Lashuel, Giovanni Dietler, Hatice Altug, Francesco Simone Ruggeri, Dordaneh Etezadi, John Blaine Warner IV

Plasmonic nanoantennas offer new applications in mid-infrared (mid-IR) absorption spectroscopy with ultrasensitive detection of structural signatures of biomolecules, such as proteins, due to their strong resonant near-fields. The amide I fingerprint of a ...

Springer Nature2017

Multi-resonant compact nanoaperture with accessible large nearfields

Hatice Altug, Dordaneh Etezadi

We present a compact and multi-resonant aperture system supporting large local electromagnetic fields, which is highly advantageous for applications demanding high signal-to-noise ratio. The system is composed of subwavelength H-shaped apertures with exten ...

2015

Performance metrics and enabling technologies for nanoplasmonic biosensors

Hatice Altug

Nanoplasmonic structures can tightly confine light onto a material's surface to probe biomolecular interactions not easily accessed by other sensing techniques. New and exciting developments in nanofabrication processes, nano-optical trapping, graphene dev ...

Nature Research2018

Quantifying the Limits of Detection of Surface-Enhanced Infrared Spectroscopy with Grating Order-Coupled Nanogap Antennas

Hatice Altug, Andreas Tittl, Aurélian Michel John-Herpin

Infrared spectroscopy is widely used for biomolecular studies, but struggles when investigating minute quantities of analytes due to the mismatch between vibrational cross sections and IR wavelengths. It is therefore beneficial to enhance absorption signal ...

2018

Spatiotemporal Interrogation of Single Spheroids Using Multiplexed Nanoplasmonic-fluorescence Imaging

Matthias Lütolf, Hatice Altug, Yen-Cheng Liu, Luis Francisco Lorenzo Martin, Saeid Ansaryan, Yung-Cheng Chiang, Jiayi Tan

Advances in organoid models, as ex vivo mini-organs, and the development of screening imaging technologies have continuously driven each other forward. A complete understanding of organoids requires detailed insights into the intertwined intraorganoid and ...

WILEY-V C H VERLAG GMBH2025

Infrared Metasurface Augmented by Deep Learning for Monitoring Dynamics between All Major Classes of Biomolecules

Hatice Altug, Aurélian Michel John-Herpin, Deepthy Kavungal

Insights into the fascinating molecular world of biological processes are crucial for understanding diseases, developing diagnostics, and effective therapeutics. These processes are complex as they involve interactions between four major classes of biomole ...

Wiley-V C H Verlag Gmbh2021

Imaging-based Optofluidic Biosensors Enabled by All-dielectric metasurfaces

Michele De Palma, Hatice Altug, Chiara Cianciaruso, Yasaman Jahani, Eduardo Romero Arvelo

We present optofluidic label-free biosensors leveraging high quality-factor resonances emanated from bound-states-in-the-continuum and novel data processing. The sensors are based on imaging and offer solutions to remove sophisticated spectroscopy instrume ...

IEEE2021

High-Contrast Infrared Absorption Spectroscopy via Mass-Produced Coaxial Zero-Mode Resonators with Sub-10 nm Gaps

Hatice Altug, Aurélian Michel John-Herpin

We present a wafer-scale array of resonant coaxial nanoapertures as a practical platform for surface-enhanced infrared absorption spectroscopy (SEIRA). Coaxial nanoapertures with sub-10 nm gaps are fabricated via photolithography, atomic layer deposition o ...

American Chemical Society (ACS)2018

Magnesium Optrodes for Real-Time Optical Monitoring of Water Transport in Ultrathin Encapsulations for Bioelectronics

Yves Leterrier, Stéphanie Lacour, Hatice Altug, Massimo Mariello, Deepthy Kavungal, Mélanie Nelly Rouèche, Marion Bianca Cleusix

Recent studies investigated the hydrolysis of Magnesium (Mg) thin films, highlighting their potential use in biodegradable devices. Quantitatively monitoring the degradation rate and morphological changes of Mg through optical methods and light-delivery de ...

2024

Plasmonic biosensor enabled by resonant quantum tunnelling

Hatice Altug, Ivan Sinev, Mikhail Masharin

Metasurfaces provide an ideal platform for optical sensing because they produce strong light-field confinement and enhancement over extended regions that allow us to identify deep-subwavelength layers of organic and inorganic molecules. However, the requir ...

Nature Publishing Group2025

Stepwise release of Activin-A from its inhibitory prodomain is modulated by cysteines and requires furin coexpression to promote melanoma growth

Hatice Altug, Daniel Constam, Benjamin Marcel Daniel Rothé, Saeid Ansaryan, Katarina Pinjusic, Manon Bulliard, Pierpaolo Ginefra, Céline Emmanuelle Schmuziger

The Activin-A precursor dimer can be cleaved by furin, but how this proteolytic maturation is regulated in vivo and how it facilitates access to signaling receptors is unclear. Here, analysis in a syngeneic melanoma grafting model shows that without furin ...

2024

Bioinspired Three-Component System to Prepare Full-Color Functional Biomimetic Pigments

Yuhe Shen, Hatice Altug

Nature provides a great source of inspiration for the development of sustainable materials with excellent properties, among which melanin with optical, electronic, and radiation protection properties are considered to be promising coloring materials. Howev ...

AMER CHEMICAL SOC2024