Publications by Hatice Altug | EPFL Graph Search

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We present optofluidic label-free biosensors leveraging high quality-factor resonances emanated from bound-states-in-the-continuum and novel data processing. The sensors are based on imaging and offer solutions to remove sophisticated spectroscopy instrume ...

Recent studies investigated the hydrolysis of Magnesium (Mg) thin films, highlighting their potential use in biodegradable devices. Quantitatively monitoring the degradation rate and morphological changes of Mg through optical methods and light-delivery de ...

Metasurfaces provide an ideal platform for optical sensing because they produce strong light-field confinement and enhancement over extended regions that allow us to identify deep-subwavelength layers of organic and inorganic molecules. However, the requir ...

The Activin-A precursor dimer can be cleaved by furin, but how this proteolytic maturation is regulated in vivo and how it facilitates access to signaling receptors is unclear. Here, analysis in a syngeneic melanoma grafting model shows that without furin ...

y Sepsis is a condition characterized by a severe stage of blood-infection often leading to tissue damage, organ failure and finally death. Fast diagnosis and identification of the sepsis stage (sepsis, severe sepsis or septic shock) is critical for the pa ...

Organoid tumor models have emerged as a powerful tool in the fields of biology and medicine as such 3D structures grown from tumor cells recapitulate better tumor characteristics, making these tumoroids unique for personalized cancer research. Assessment o ...

The screening and analysis of T cells functional avidity for specific tumor-associated antigens is crucial for the development of personalized immunotherapies against cancer. The affinity and kinetics of a T cell receptor (TCR) binding to the peptide-major ...

Modern devices require the tuning of the size, shape and spatial arrangement of nano-objects and their assemblies with nanometre-scale precision, over large-area and sometimes soft substrates. Such stringent requirements are beyond the reach of conventiona ...

In this paper, we both experimentally and numerically introduce a dual-resonant metamaterial based on subwavelength Jerusalem cross-shaped apertures. We numerically investigate the physical origin of the dual-resonant behavior, originating from the constit ...

Continuous monitoring of acute inflammation can become a very important next step for guiding therapeutic interventions in severely ill patients. This Perspective discusses the current medical need for patients with acute inflammatory diseases and the pote ...

Chiral metasurfaces provide invaluable tools for controlling structured light required for biosensing, photochemistry, holography, and quantum photonics. Here we suggest and realize a universal strategy for engineering chiral response of resonant metasurfa ...

Recently, bowtie-shaped apertures have received significant attention due to their extraordinary ability to generate dramatic field enhancement and light confinement in nanometer scale. In this article, we investigate both experimentally and theoretically ...

We design high-Q metasurfaces with resonant wavelengths in mid-IR varying continuously along the sample. We demonstrate tunable rainbow generation of high harmonics as we vary the pump wavelength and the coordinate along the metasurface. ...

The present invention relates to an infrared absorption spectroscopy apparatus including an infrared transparent substrate comprising a first and second surface, an array of plasmonic nano-antennas arranged on the first surface of the infrared transparent ...

Molecular spectroscopy provides unique information on the internal structure of biological materials by detecting the characteristic vibrational signatures of their constituent chemical bonds at infrared frequencies. Nanophotonic antennas and metasurfaces ...

Proteins secreted by cells play significant roles in mediating many physiological, developmental, and pathological processes due to their functions in intra/intercellular communication and signaling. Conventional end-point methods are insufficient for unde ...

Plasmonic nanohole arrays have received significant attention, as they have highly advantageous optical properties for ultrasensitive and label-free biosensing applications. Currently, most of these subwavelength periodic apertures are mainly implemented o ...

In an effort to address the requirements of next-generation healthcare systems, including personalized medicine, point-of-care diagnostics, and global health surveillance, I will introduce imaging-based portable nanoplasmonic biosensors integrated with mic ...

Interaction between localized plasmons in isolated proximal nanostructures is a well-studied phenomenon. Here we explore plasmon-plasmon interactions in connected extended systems. Such systems can now be easily produced experimentally using graphene. Howe ...

Hatice Altug

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Imaging-based Optofluidic Biosensors Enabled by All-dielectric metasurfaces

Magnesium Optrodes for Real-Time Optical Monitoring of Water Transport in Ultrathin Encapsulations for Bioelectronics

Plasmonic biosensor enabled by resonant quantum tunnelling

Stepwise release of Activin-A from its inhibitory prodomain is modulated by cysteines and requires furin coexpression to promote melanoma growth

Early sepsis diagnosis via protein and miRNA biomarkers using a novel point-of-care photonic biosensor

Nanoplasmonic Single-Tumoroid Microarray for Real-Time Secretion Analysis

Two-Dimensional Label-Free Affinity Analysis of Tumor-Specific CD8 T Cells with a Biomimetic Plasmonic Sensor

Self-assembly of nanostructured glass metasurfaces via templated fluid instabilities

Dual-band plasmonic resonator based on Jerusalem cross-shaped nanoapertures

Continuous Biosensing to Monitor Acute Systemic Inflammation, a Diagnostic Need for Therapeutic Guidance

Programmable Huygens' metasurfaces for active optical phase control

Chirality encoding in resonant metasurfaces governed by lattice symmetries

Theoretical and experimental analysis of subwavelength bowtie-shaped antennas

Rainbow dielectric metasurfaces for tunable resonant generation of high harmonics

Infrared absorption spectroscopy

Metasurface‐based molecular biosensing aided by artificial intelligence

Real-time monitoring of single-cell secretion with a high-throughput nanoplasmonic microarray

Plasmonic Nanohole Arrays on a Robust Hybrid Substrate for Highly Sensitive Label-Free Biosensing

Integrated Nanophotonic Biosensors for Point-of Care Diagnostics and Bioanalytical Applications

Plasmon coupling in extended structures: Graphene superlattice nanoribbon arrays