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Sandro Carrara

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Related publications (297)

Gold nanoparticles mediated label-free capacitance detection of cardiac troponin I

It has been already proved that electrical capacitance increases at the electrode surface due to binding of highly charged antigens on the biointerface. In this paper, this capacitance change was used to demonstrate a novel detection for cardiac troponin I ...

2012

Carbon Nanotubes With Different Orientations for Electrochemical Biodevices

Giovanni De Micheli, Sandro Carrara, Irene Taurino

Carbon nanotubes (CNTs) improve the sensitivity of electrochemical biosensors. An optimized CNT/trasducer inte- gration is required to realize accurate devices. The nanotube orientation on the sensor electrode is a key parameter. The role of the sidewalls ...

Institute of Electrical and Electronics Engineers2012

A Self-Contained System With CNTs-Based Biosensors for Cell Culture Monitoring

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Jacopo Olivo

Biosensors have been applied to disparate fields, especially for endogenous compounds such as glucose and lactate. The main areas of application are certainly related to medical and diagnostic purposes. However, metabolic monitoring can be also of interest ...

2012

Electrochemical Detection of Anti-Breast-Cancer Agents in Human Serum by Cytochrome P450-Coated Carbon Nanotubes

Giovanni De Micheli, Sandro Carrara, Camilla Baj-Rossi

We report on the electrochemical detection of anti-cancer drugs in human serum with sensitivity values in the range of 8–925 nA/µM. Multi-walled carbon nanotubes were functionalized with three different cytochrome P450 isoforms (CYP1A2, CYP2B6, and CYP3A4) ...

2012

Fully Integrated Biochip Platforms for Advanced Healthcare

Catherine Dehollain, Giovanni De Micheli, Andrea Cavallini, Sandro Carrara, Jacopo Olivo, Irene Taurino, Camilla Baj-Rossi, Seyedeh Sara Ghoreishizadeh, Wayne Burleson

Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring ...

Mdpi Ag2012

Design, fabrication, and test of a sensor array for perspective biosensing in chronic pathologies

Giovanni De Micheli, Andrea Cavallini, Sandro Carrara, Camilla Baj-Rossi, Seyedeh Sara Ghoreishizadeh

Biosensing for chronic pathologies requires the simultaneous monitoring of different parameters such as drug concentrations, inflammation status, temperature and pH. In this paper we discuss the design, fabrication and test of a sensor array hosting five b ...

2012

Targeting of multiple metabolites in neural cells monitored by using protein-based carbon nanotubes

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Giovanna Del Vecchio

Microdevices dedicated to monitor metabolite levels have recently enabled many applications in the field of cell analysis, to monitor cell growth and development of numerous cell lines. By combining the traditional technology used for electrochemical biose ...

2011

Biochips for Regenerative Medicine: Real-time Stem Cell Continuous Monitoring as Inferred by High-Throughput Gene Analysis

Giovanni De Micheli, Sandro Carrara, Giovanna Del Vecchio

Regenerative medicine is a novel clinical branch aiming at the cure of diseases by replacement of damaged tissues. The crucial use of stem cells makes this area rich of challenges, given the poorly understood mechanisms of differentiation. One highly neede ...

2011

Comparison of Three Methods of Biocompatible Multi-Walled Carbon Nanotubes Confinement for the Development of Implantable Amperometric Adenosine-5′-Triphosphate Biosensors

Giovanni De Micheli, Andrea Cavallini, Sandro Carrara

An amperometric biosensor for adenosine 5 -triphosphate (ATP) was developed applying a competitive assay of two glucose converting enzymes: glucose oxidase (GOD) and hexokinase (HEX). Competition between GOD and HEX for glucose in presence of ATP, lead to ...

American Scientific Publishers2011

Energy Harvesting and Remote Powering for Implantable Biosensors

Giovanni De Micheli, Sandro Carrara, Jacopo Olivo

The paper reviews some popular techniques to harvest energy for implantable biosensors. For each technique, the advantages and drawbacks are discussed. Emphasis is placed to the inductive links, able to deliver power wirelessly through the biological tissu ...

Institute of Electrical and Electronics Engineers2011

Highly Sensitive Carbon Nanotube-Based Sensing for Lactate and Glucose Monitoring in Cell Culture

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Giovanna Del Vecchio

Monitoring of metabolic compounds in cell cultures can provide real-time information of cell line status. This is particularly important in those lines not fully known, as the case of embryonic and mesenchymal cells. On the other hand, such approach can pa ...

Institute of Electrical and Electronics Engineers2011

Long-term Biosensors for Metabolite Monitoring by using Carbon Nanotubes

Giovanni De Micheli, Cristina Boero, Sandro Carrara

The key-point for the development of an amperometric sensor is the immobilization of the enzyme. In the present work we use biosensors based on glucose oxidase (GOD) onto electrodes nanostructured with carbon nanotubes (CNT), to be employed in cell culture ...

2011

New Insight on Bio-sensing by Nano-fabricated Memristors

Yusuf Leblebici, Giovanni De Micheli, Davide Sacchetto, Sandro Carrara

We report here on a new insight for bio-sensing based on the memristive effect of functionalized Schottky-barrier memristive silicon nanowire in dry environment. The device concept is discussed. Electrical measurements confirm the bio-detection by the narr ...

2011

Biofuel Cells and Inductive Powering as Energy Harvesting Techniques for Implantable Sensors

Giovanni De Micheli, Sandro Carrara, Jacopo Olivo

In order to increase the power autonomy of implantable sensors, energy harvesters can aid and, in certain cases, substitute implantable batteries. The paper describes two promising techniques among the approaches presented in literature: biofuel cells and ...

2011

Comparing the enhanced sensing interfaces of differently oriented carbon nanotubes onto silicon for bio-chip applications

Giovanni De Micheli, Sandro Carrara, Irene Taurino

Carbon nanotubes improve the sensitivity of electrochemical biochips. An optimized integration of the nano/bio/CMOS interface is required to realize accurate and low-cost sensors for applications in personalized medicine. The nanotubes orientation on the c ...

2011

An Integrated Platform for Advanced Diagnostics

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Seyedeh Sara Ghoreishizadeh

The objective of this work is the systematic study of the use of electrochemical readout for advanced diagnosis and drug monitoring. Whereas to date various electrochemical principles have been studied and successfully tested, they typically operate on a s ...

2011

Nutrichip: an integrated microfluidic system for in vitro investigation of the immunemodulatory function of dairy products

Martinus Gijs, Paolo Silacci, Guy Vergères, Sandro Carrara, Flurina Schwander, Hamideh Jafarpoorchekab

We introduce the concept of the NutriChip, a miniaturized artificial human gastrointestinal tract (GIT) for investigating the potential of immuno-modulatory function of dairy food. More specifically, we are investigating the effect of digested milk on immu ...

2011

A Special Issue on Nanoengineered Silicon: Technology and Applications

Lucia Baldi Unser, Sandro Carrara

2011

VHDL-AMS Model of an Electrochemical Cell to Design VLSI Bio-Chips

Alain Vachoux, Yusuf Leblebici, Giovanni De Micheli, Sandro Carrara, Marialaura Beltrandi

This paper presents a new VHDL-AMS behavioral model of an electrochemical cell suitable for the design of VLSI bio-chips. Existing models are mainly equivalent circuit macromodels using electrical primitives, which hardly fit the actual behavior of biosens ...

2011

A new ethylene glycol-silane monolayer for highly-specific DNA detection on Silicon Chips

Edoardo Charbon, Giovanni De Micheli, Andrea Cavallini, Sandro Carrara

Monolayer thin films with ethylene-glycol function onto gold surfaces by using thiols have been extensively investigated. They have been proposed as precursors for applications to bio-detection, where their hydrophilic character improves both specificity a ...

Emerald2010

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