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Sandro Carrara

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Related publications (297)

Memristive Biosensors Under Varying Humidity Conditions

Yusuf Leblebici, Giovanni De Micheli, Davide Sacchetto, Sandro Carrara, Camilla Baj-Rossi, Francesca Puppo, Akshat Dave

We attempt to examine the potential of silicon nanowire memristors in the field of nanobiosensing. The mem- ristive devices are crystalline Silicon (Si) Nanowires (NWs) with Nickel Silicide (NiSi) terminals. The nanowires are fabricated on a Silicon-on-Ins ...

Institute of Electrical and Electronics Engineers2014

High Sensitive Detection in Tumor Extracts with SiNW-FET in-Air Biosensors

Giovanni De Micheli, Sandro Carrara, Francesca Puppo

We have already demonstrated that high quality SiNW-FETs can be used to sense very low concentration range (fM) of pathogenic factors in controlled PBS. In this work we show, for the first time, Silicon Nanowire Field Effect Transistors (SiNW-FET) as biose ...

IEEE2014

Novel Readout Circuit for Memristive Biosensors in Cancer Detection

Giovanni De Micheli, Sandro Carrara, Francesca Puppo, Ali Zaher

We present a novel circuit for the automated and quick characterization of an array of experimental memristive nanowires that are functionalized as biosensors. Successfully functionalized nanowires will express the concentration of target molecules by hyst ...

IEEE2014

Quantitative Estimation of Biological Cell Surface Receptors by Segmenting Conventional Fluorescence Microscopy Images

Paolo Silacci, Guy Vergères, Giovanni De Micheli, Julien Michel Ghaye, Sandro Carrara, Chiara Succa, Danilo Demarchi

State-of-the-art techniques for measuring and monitoring gene level expression rely on messenger RNA (mRNA) extraction and quantification, usually based on the concept of reverse transcription polymerase chain reaction. In this paper, we take adva ...

Ieee2014

Memristive sensors for pH measure in dry conditions

Massimiliano Di Ventra, Giovanni De Micheli, Sandro Carrara, Francesca Puppo

A large progress in pH sensing with nanowire based ion-sensitive field-effect transistors (ISFETs) has been demonstrated over the years. The electrochemical reactions occurring at the wire surface-to-electrolyte interface play a key role in the detection o ...

Elsevier Science Bv2014

Sub-mW Reconfigurable Interface IC for Electrochemical Sensing

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Camilla Baj-Rossi, Seyedeh Sara Ghoreishizadeh

The IronIC project has the aim of developing a fully implantable and remotely powered platform for the real- time monitoring of human metabolites. In this paper we present a mixed-signal interface IC for the electrochemical sensing data acquisition chain. ...

IEEE2014

Full Fabrication and Packaging of an Implantable Multi-panel Device for Monitoring of Metabolites in Small Animals

Catherine Dehollain, Giovanni De Micheli, Sandro Carrara, Enver Gürhan Kilinç, Camilla Baj-Rossi, Seyedeh Sara Ghoreishizadeh, Daniele Casarino

In this work, we show the realization of a fully-implantable device for monitoring free-moving small animals. The device integrates a microfabricated sensing platform, a coil for power and data transmission and two custom designed integrated circuits. The ...

Ieee-Inst Electrical Electronics Engineers Inc2014

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor

Giovanni De Micheli, Andrea Cavallini, Sandro Carrara, Camilla Baj-Rossi

This paper reports the characterization of an electrochemical biosensor for the continuous monitoring of Naproxen based on cytochrome P450. The electrochemical biosensor is based on the drop-casting of multi-walled carbon-nanotubes (MWCNTs) and microsomal ...

Elsevier2014

Characterization of Standard CMOS Compatible Photodiodes and Pixels for Lab-on-Chip Devices

Yusuf Leblebici, Giovanni De Micheli, Gözen Köklü, Sandro Carrara

High quality CMOS image sensors are of great importance for LoC - Lab-on-Chip devices based on optical measurements. The main target in these devices is to minimize the cost and area while achieving a good resolution. The performance parameters of image se ...

2013

An event-detection high dynamic range CMOS image sensor

Yusuf Leblebici, Giovanni De Micheli, Gözen Köklü, Sandro Carrara

A novel CMOS image sensor is proposed to overcome the analog design limitations in Active Pixel Sensors - APS and large area overcome in Digital Pixel Sensors - DPS for use in bio-medical applications. The design includes a pixel level event generation mec ...

2013

Lab-on-a-chip implants: a mini laboratory under the skin

Giovanni De Micheli, Cristina Boero, Sandro Carrara

2013

Applications of Multi-Terminal Memristive Devices: A Review

Yusuf Leblebici, Giovanni De Micheli, Michail Zervas, Davide Sacchetto, Sandro Carrara, Pierre-Emmanuel Julien Marc Gaillardon

Memristive devices have the potential for a complete renewal of the electron devices landscape, including memory, logic and sensing applications. This is especially true when considering that the memristive functionality is not limited to two-terminal devi ...

Ieee-Inst Electrical Electronics Engineers Inc2013

A Linear Approach to Multi-Panel Sensing in Personalized Therapy for Cancer Treatment

Giovanni De Micheli, Sandro Carrara, Camilla Baj-Rossi

In this paper, a new approach for evaluating the performance of a multi-panel biosensor using linear algebra is presented. With a system-level mathematical analysis based on graphs and linear algebra, we formulate a new approach for contributions decouplin ...

Institute of Electrical and Electronics Engineers2013

Comparative Performance of Different Nanostructured Electrochemical Sensors on Insulin Detection

Giovanni De Micheli, Sandro Carrara, Lucia Grassi

New advancements in the management of type I diabetic patients (T1DM) call for a new generation of monitoring systems based upon an array of metabolic biosensors including sensors for insulin detection. Blood insulin values are always less than 270 pM; the ...

2013

Remote System for Monitoring Animal Models With Single-Metabolite Bio-Nano-Sensors

Léandre Bolomey, Eric Meurville, Giovanni De Micheli, Cristina Boero, Andrea Cavallini, Sandro Carrara

A novel system for remote monitoring of metabolism in an animal model is proposed in this paper. The system is obtained by integrating bio-nano-sensors to detect single- metabolites, an electrochemical front-end made with off-the-shelf components, a radio ...

Institute of Electrical and Electronics Engineers2013

Image thresholding techniques for localization of sub-resolution fluorescent biomarkers

Paolo Silacci, Guy Vergères, Giovanni De Micheli, Julien Michel Ghaye, Sandro Carrara, Madhura Avinash Kamat

In this article, we explore adaptive global and local segmentation techniques for a lab-on-chip nutrition monitoring system (NutriChip). The experimental setup consists of Caco-2 intestinal cells that can be artificially stimulated to trigger an immune res ...

Wiley-Blackwell2013

A Configurable IC to Control, Readout and Calibrate an Array of Biosensors

Giovanni De Micheli, Sandro Carrara, Seyedeh Sara Ghoreishizadeh

We present a novel integrated circuit for a biosensing data acquisition chain. The circuit controls and reads out five bimolecular sensors as well as pH and temperature sensors for biosensor calibration. The IC supports both chronoamperometry (CA) a ...

2013

Guest Editorial-ISCAS 2012 Special Issue

Sandro Carrara

Ieee-Inst Electrical Electronics Engineers Inc2013

Electronic Implants: Power Delivery and Management

Giovanni De Micheli, Sandro Carrara, Jacopo Olivo, Seyedeh Sara Ghoreishizadeh

A power delivery system for implantable biosensors is presented. The system, embedded into a skin patch and located directly over the implantation area, is able to transfer up to 15 mW wirelessly through the body tissues by means of an inductive link. The ...

2013

Superior sensing performance of multi-walled carbon nanotube-based electrodes to detect unconjugated bilirubin

Giovanni De Micheli, Sandro Carrara, Irene Taurino

The direct electrochemical behaviour of bilirubin in the physio-pathological concentration range and at physio- logical pH was investigated by cyclic voltammetry. Nanostructured electrodes with a thin film of multi-walled carbon nanotubes exhibited a highe ...

Elsevier2013

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