Home

Person

Tobias Kober

About
Privacy
Disclaimer

Graph Chatbot

Related publications (151)

Fast and high-resolution myelin water imaging: Accelerating multi-echo GRASE with CAIPIRINHA

Jean-Philippe Thiran, Reto Meuli, Tobias Kober, Alessandro Daducci, Tom Hilbert, Gian Franco Piredda, Erick Jorge Canales Rodriguez, Marco Pizzolato

Purpose Although several MRI methods have been explored to achievein vivomyelin quantification, imaging the whole brain in clinically acceptable times and sufficiently high resolution remains challenging. To address this problem, this work investigates the ...

Wiley2021

Probing myelin content of the human brain with MRI: A review

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Gian Franco Piredda

Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured by myelin-insulating sheaths surrounding axons. Human cognition, sensation, and motor functions rely on the integrity of these layers, and demyelinating diseases o ...

WILEY2021

Magnetization-prepared 2 Rapid Gradient-Echo MRI for B-1 Insensitive 3D T1 Mapping of Hip Cartilage: An Experimental and Clinical Validation

Tobias Kober

Background: Often used for T1 mapping of hip cartilage, three-dimensional (3D) dual-flip-angle (DFA) techniques are highly sensitive to flip angle variations related to B-1 inhomogeneities. The authors hypothesized that 3D magnetization-prepared 2 rapid gr ...

RADIOLOGICAL SOC NORTH AMERICA2021

Dynamic distortion correction for functional MRI using FID navigators

Tobias Kober

Purpose To develop a method for slice-wise dynamic distortion correction for EPI using rapid spatiotemporal B(0)field measurements from FID navigators (FIDnavs) and to evaluate the efficacy of this new approach relative to an established data-driven techni ...

WILEY2021

Fluid and White Matter Suppression Imaging and Voxel-Based Morphometric Analysis in Conventional Magnetic Resonance Imaging-Negative Epilepsy

Tobias Kober

Purpose: Delineation of subtle lesions in magnetic resonance imaging (MRI)-negative patients is of great importance in preoperative epilepsy evaluation. The aim of our study was to explore the diagnostic value of the novel fluid and white matter suppressio ...

FRONTIERS MEDIA SA2021

Synthetic T-2-weighted images of the lumbar spine derived from an accelerated T-2 mapping sequence: Comparison to conventional T(2)w turbo spin echo

Tobias Kober, Tom Hilbert

Objectives: To evaluate the diagnostic usefulness of synthetic T2-weighted images of the lumbar spine derived from ten-fold undersampled k-space data using GRAPPATINI, a combination of a model-based approach for rapid T2 and M0 quantification (MARTINI) ext ...

ELSEVIER SCIENCE INC2021

Periventricular gradients of T-1 z-scores correlate with disability in early multiple sclerosis

Bénédicte Marie Maréchal, Tobias Kober, Tom Hilbert

SAGE PUBLICATIONS LTD2021

Automated assessment of paramagnetic rim lesions in multiple sclerosis patients with 3T and 7T MP2RAGE

Jean-Philippe Thiran, Meritxell Bach Cuadra, Bénédicte Marie Maréchal, Tobias Kober, Cristina Granziera, Francesco La Rosa

Paramagnetic rim lesions (PRL) in multiple sclerosis are chronic inflammatory lesions depicted in susceptibility-based MRI where high PRL lesion burden has been associated with a more aggressive disease course. As their visual detection is subjective and t ...

ISMRM2021

T-1 relaxometry abnormalities in white matter tracts predict functional systems scores in MS

Jean-Philippe Thiran, Bénédicte Marie Maréchal, Tobias Kober, Tom Hilbert

SAGE PUBLICATIONS LTD2021

Quantitative comparison of subcortical and ventricular volumetry derived from MPRAGE and MP2RAGE images using different brain morphometry software

Bénédicte Marie Maréchal, Tobias Kober

Objective In brain volume assessment with MR imaging, it is of interest to know the effects of the pulse sequence and software used, to determine whether they provide equivalent data. The aim of this study was to compare cross-sectional volumes of subcorti ...

SPRINGER2021

Free induction decay navigator motion metrics for prediction of diagnostic image quality in pediatric MRI

Tobias Kober

Purpose To investigate the ability of free induction decay navigator (FIDnav)-based motion monitoring to predict diagnostic utility and reduce the time and cost associated with acquiring diagnostically useful images in a pediatric patient cohort. ...

WILEY2021

Compressed sensing with signal averaging for improved sensitivity and motion artifact reduction in fluorine-19 MRI

Jérôme Yerly, Ruud van Heeswijk, Elena Najdenovska, Tobias Kober, Tom Hilbert

Fluorine-19 (F-19) MRI of injected perfluorocarbon emulsions (PFCs) allows for the non-invasive quantification of inflammation and cell tracking, but suffers from a low signal-to-noise ratio and extended scan time. To address this limitation, we tested the ...

WILEY2020

RimNet: A deep 3D multimodal MRI architecture for paramagnetic rim lesion assessment in multiple sclerosis

Meritxell Bach Cuadra, Tobias Kober, Hamza Kebiri, Cristina Granziera, Po-Jui Lu, Francesco La Rosa

Objectives In multiple sclerosis (MS), the presence of a paramagnetic rim at the edge of non-gadolinium-enhancing lesions indicates perilesional chronic inflammation. Patients featuring a higher paramagnetic rim lesion burden tend to have more aggressive d ...

2020

MRI-based brain volumetry and retinal optical coherence tomography as the biomarkers of outcome in acute methanol poisoning

Bénédicte Marie Maréchal, Tobias Kober

Background: Basal ganglia lesions are typical findings on magnetic resonance imaging (MRI) of the brain in survivors of acute methanol poisoning. However, no data are available on the association between the magnitude of damaged brain regions, serum concen ...

ELSEVIER2020

NovelT2Mapping for Evaluating Cervical Cancer Features by Providing QuantitativeT2Maps and Synthetic Morphologic Images: A Preliminary Study

Tobias Kober, Tom Hilbert, Yong Zhang, Meng Yang, Jie Liu

Background The application value of T(2)mapping in evaluating cervical cancer (CC) features remains unclear. Purpose To investigate the role of T(2)values in evaluating CC classification, grade, and lymphovascular space invasion (LVSI) in comparison to app ...

WILEY2020

Accelerated MP2RAGE imaging using Cartesian phyllotaxis readout and compressed sensing reconstruction

Jean-Philippe Thiran, Reto Meuli, Tobias Kober, Tom Hilbert

Purpose MP2RAGE T-1-weighted imaging has been shown to be beneficial for various applications, mainly because of its good grey-white matter contrast, its B-1-robustness and ability to derive T(1)maps. Even using parallel imaging, the method requires long a ...

WILEY2020

Rapid measurement and correction of spatiotemporal B-0 field changes using FID navigators and a multi-channel reference image

Tobias Kober

Purpose To measure spatiotemporal B-0 field changes in real time using FID navigators (FIDnavs) and to demonstrate the efficacy of retrospectively correcting high-resolution T2*-weighted images using a novel FIDnav framework. Methods A forward model of the ...

Wiley2020

Test-retest variability of brain morphometry analysis: an investigation of sequence and coil effects

Bénédicte Marie Maréchal, Tobias Kober

Background: Precise and reliable brain morphometry analysis is critical for clinical and research purposes. The magnetization-prepared rapid gradient echo (MPRAGE), multi-echo MPRAGE (MEMPRAGE) and magnetization-prepared 2 rapid acquisition gradient echo ( ...

AME PUBL CO2020

Magnetization transfer in magnetic resonance fingerprinting

Tobias Kober, Tom Hilbert

Purpose To study the effects of magnetization transfer (MT, in which a semi-solid spin pool interacts with the free pool), in the context of magnetic resonance fingerprinting (MRF). Methods Simulations and phantom experiments were performed to study the im ...

WILEY2020

Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity

Bénédicte Marie Maréchal, Tobias Kober, Mario Joao Fartaria de Oliveira, Ricardo Alberto Corredor Jerez

Neurofilament light chain (NfL) has been demonstrated to correlate with multiple sclerosis disease severity as well as treatment response. Nevertheless, additional serum biomarkers are still needed to better differentiate disease activity from disease prog ...

Nature Research2020

Page 4 of 8