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Philippe Renaud

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Related publications (301)

Temperature gradient stimulation for cell division in C. Elegans Embryos on chip

Philippe Renaud, Pierre Gönczy, Christian Adamczyk, Alexandra Bezler, Sophie Baranek Delasoie

This paper reports on a new microfluidic device for temperature stimulation of cell in in-vitro culture. Micro- electrodes in a meander shape are embedded into the microfluidic channels to generate either a temperature gradient through the culture chamber ...

2010

Continuous-flow electrical lysis device with integrated control by dielectrophoretic cell sorting

Philippe Renaud, Nicolas Demierre, Thomas Michael Braschler, Niccolo Piacentini

We present a device capable of electrical cell lysis and evaluation of lysis efficiency in continuous flow using dielectrophoretic cell sorting. We use a combination of AC electrical fields and so-called liquid electrodes to avoid bubble creation at the el ...

Royal Society of Chemistry2010

Method for fabricating micromirror for barcode reader, involves forming holes having diameter less than width of arms on both side of micromirror and wafer and on edges of region separating wafer and micromirror by etching arms

Philippe Renaud, Faouzi Khechana, Nicolas Abelé

A method for fabricating a micromirror in a wafer, including the steps of: depositing and etching layers forming two arms; etching the wafer such that in the back face only a thin portion of the wafer remains in the region of formation of the micromirror a ...

2010

Multiple-frequency Impedance Measurements in Continuous Flow for the Evaluation of Electrical Lysis of Yeast Cells

Philippe Renaud, Niccolo Piacentini, Willyan Hasenkamp Carreira

his paper reports on an electrical lysis device with integrated cell counting and evaluation of the lysis efficiency by multiplefrequency impedance measurements. Conventional techniques use chemical reagents to lyse cells, causing unwanted interference wit ...

Elsevier2010

Novel radiation hard microfabricated scintillation detectors with high spatial resolution

Philippe Renaud, Alessandro Mapelli, Sébastien Jiguet, Noelia Vico Triviño

A novel liquid scintillation detector with high spatial resolution is being developed with standard microfabrication techniques. It consists of a dense array of scintillating waveguides obtained by filling microfluidic channels with an organic liquid scint ...

Elsevier2010

Implantable probe for stimulating neurological target e.g. neurons and subthalamic nucleus, has several microelectrode elements arranged at distal end of elongated probe shaft, and electrical contact arranged proximally along shaft

Philippe Renaud, André Mercanzini

Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged alon ...

2010

Scintillation particle detection based on microfluidics

Philippe Renaud, Alessandro Mapelli, Sébastien Jiguet, Noelia Vico Triviño

A novel type of particle detector based on scintillation, with precise spatial resolution and high radiation hardness, is being studied. It consists of a single microfluidic channel filled with a liquid scintillator and is designed to define an array of sc ...

Elsevier2010

Optimization of microfluidic single cell trapping for long-term on-chip culture

Matthias Lütolf, Philippe Renaud, Jonas Marcel Lätt, Stefan Kobel, Ana Valero

The poor efficiency of microfluidic single cell trapping is currently restricting the full potential of state-of-the-art single cell analyses. Using fluid dynamics simulations in combination with particle image velocimetry to systematically optimize trap a ...

Royal Society of Chemistry2010

A miniaturized continuous dielectrophoretic cell sorter and its applications

Philippe Renaud, Nicolas Demierre, Thomas Michael Braschler, Ana Valero

There is great interest in highly sensitive separation methods capable of quickly isolating a particular cell type within a single manipulation step prior to their analysis. We present a cell sorting device based on the opposition of dielectrophoretic forc ...

American Institute of Physics2010

Neurite guidance through 3D hydrogel layers in a microfluidic environment

Philippe Renaud, Anja Kunze, Robert Meissner

Neuronal cell culture models in vitro are often restricted to 2D surfaces. Engineering the complexity of the neuronal microenvironment in microfluidic systems can help to generate more tissue like cultures. We have developed a new neuronal cell culturing s ...

2010

Explosion of energy demand for air cooling in summer: perspectives and solutions (EEDACS)

Claude-Alain Roulet, Philippe Renaud, Darren Robinson, Frédéric Haldi

The Swiss Federal Office of Energy has published directives in order to limit the increase of electrical energy consumption to a maximum of 5% in 2010 in comparison with 2000. To reach this goal, clear measures have to be taken regarding the installation a ...

EPFL2009

Conducting polymer microactuators operating in air

Valérie Devaud, Philippe Renaud

We report for the first time on microsized conducting polymer actuators, which operate in air and in liquids. These actuators are potentially useful for a wide range of applications from biotechnology to microrobots. Furthermore, the actuators are fabricat ...

2009

B-Alkylcatecholborane-Mediated Tandem Radical Conjugated Addition-Aldol Cyclization

Philippe Renaud, Kurt Schenk

A one-pot procedure involving radical conjugate addition of B-alkylcatecholboranes to enones followed by intramolecular aldol reaction is reported. Application to the stereoselective synthesis of monocyclic and bicyclic products with up to four contiguous ...

2009

Diastereoselectivity Control of the Radical Carboazidation of Substituted Methylenecyclohexanes

Philippe Renaud, Kurt Schenk

[Graphics] ...

2009

Microfluidic system based on thermoexpandable polymer for on chip blood coagulation testing

François Bianchi, Philippe Renaud, Lynda Metref, Raphaël Goetschmann

This paper describes a simple system for the actuation of a biological fluid through micro-channels with a thermoactivated polymer actuator. This system is of interest for the development of single-use diagnostic test-strips since the actuation of the samp ...

2009

High-Fidelity Printing Strategies for Printing 3D Vascular Hydrogel Structures

Matthias Lütolf, Philippe Renaud, Jürgen Brugger, Thomas Michael Braschler, Kristopher Pataky

Vascularization arguably poses the most significant hurdle for the success of most biomaterials-based tissue engineering therapies. In this work, we report two printing strategies that permit the 3D Inkjet printing of fluorescent alginate hydro gels into o ...

Soc Imaging Science & Technology, 7003 Kilworth Lane, Springfield, Va 22151 Usa2009

Oxidation of Catecholboron Enolates with TEMPO

Philippe Renaud, Kurt Schenk

Wiley-VCH Verlag GmbH2009

Biochip with E. coli bacteria for detection of arsenic in drinking water

Philippe Renaud, Harald Van Lintel, Joël Theytaz, Jan Roelof van der Meer, Thomas Michael Braschler

Arsenic and other pollutants are often present in trace amounts in drinking water in a number of countries. In aqueous solutions the sensitivity of arsenic- responsive bacterial bioreporters is far better than the performance of chemical field test kits. H ...

Elsevier2009

Efficient high-thoughput microfluidic trapping of single cells

Matthias Lütolf, Philippe Renaud, Ana Valero

2009

Direct measurement of diffusing proteins in nanochannels using fluorescence correlation spectroscopy

Philippe Renaud, Arnaud Bertsch, Theo Lasser, Nicolas Durand, Raphaël Goetschmann

Transport of proteins in liquid-filled nanometer-sized apertures with charged surfaces based on both diffusion and convective flow is investigated with the use of fluorescence correlation spectroscopy. The measured fluctuations of fluorescence allow the ev ...

Elsevier2009

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