Course

BIO-471: Cancer biology I

Summary

The course covers in detail molecular mechanisms of cancer development with emphasis on cell cycle control, genome stability, oncogenes, tumor suppressor genes, signaling pathways involved in cancer, genomic cancer analysis and rational cancer therapies.

Lectures

Instructor

Elisa Oricchio

Expertise Cancer geneticsMouse modelsTherapyStem cellsLymphoma Teaching & PhD PhD Students Vamsi Krishna Polavarapu, Asli Ece Kasapoglu, Konstantina Georgakopoulou, Eleni Balli Past EPFL PhD Students Maria Christine Donaldson, Elena Battistello, Daniel Pereira Duarte, Frédérica Schyrr, Ruxandra-Andreea Lambuta, Aaron Simone Petruzzella, Jixing Zhong, Justine Epiney Courses Cancer biology I BIO-471 The course covers in detail molecular mechanisms of cancer development with emphasis on cell

Official source

https://edu.epfl.ch/coursebook/en/cancer-biology-i-BIO-471

Moodle Page

http://go.epfl.ch/BIO-471

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Summary

Lectures

Instructor

Elisa Oricchio

Official source

https://edu.epfl.ch/coursebook/en/cancer-biology-i-BIO-471

Moodle Page

http://go.epfl.ch/BIO-471

About this result

Lectures in this course (30)

Cancer Biology: Hallmarks and Mechanisms

Covers the hallmarks of cancer, oncogenes, tumor suppressor genes, metastasis, and genetic alterations driving tumorigenesis.

BRCA2 Mutations: Mechanisms and Implications

Explores BRCA2 mutations, DNA repair mechanisms, and therapeutic implications for BRCA mutant cancers.

DNA Repair Mechanisms

Explores DNA repair mechanisms, DNA damage response, and synthetic lethality in cancer.

Cell Cycle Regulation: R-point and Telomere Maintenance

Explores the deregulation of the R-point transition in cancer and the mechanisms of telomere maintenance, along with protein-protein interactions.

RPA Regulation: ATR-ATRIP Complex and DNA Damage

Explores the regulation of the ATR-ATRIP complex by RPA in response to DNA damage, including Chk1 phosphorylation and ssDNA binding.

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