Course

CH-317: Drug discovery and development

Summary

This course discusses the molecular basis of diseases and how drugs work. Concepts and processes employed in today's drug discovery and development are covered. The first part of the course focuses on small molecule drugs and the second one on biotherapeutics.

Lectures

Instructor

Christian Heinis

Teaching & PhD PhD Students Thomas Julien Denis Emel, Alessandro Scapozza, Nathan Moïse De Sadeleer, Florian Handel, Hugo André Clerc, Frédéric Brantschen, Grégoire Menoud, Ines Michrafy, Jonathan Schmitt, Laura Elena Massaad Past EPFL PhD Students Jeremy Touati, Shiyu Chen, Sophie Venet-Bonnot, Lisa Pollaro, Inmaculada Rentero Rebollo, Philippe Diderich, Charlotte Urech-Varenne, Silvia Bellotto, Davide Bertoldo, Alessandro Zorzi, Camille Villequey, Jonas Alfred Karl Wilbs, Grigory Karateev, Vanessa Carle

Official source

https://edu.epfl.ch/coursebook/en/drug-discovery-and-development-CH-317

Moodle Page

http://go.epfl.ch/CH-317

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Summary

Lectures

Instructor

Christian Heinis

Official source

https://edu.epfl.ch/coursebook/en/drug-discovery-and-development-CH-317

Moodle Page

http://go.epfl.ch/CH-317

About this result

Lectures in this course (13)

Peptide Therapeutics

Explores the development and advantages of peptide therapeutics, including conversion into peptidomimetics and solid phase peptide synthesis.

Cyclic Peptides and Macrocycles

Explores cyclic peptides and macrocycles, their applications in drug development, and the role of bicyclic peptides in targeting specific proteins.

DNA-Encoded Libraries

Explores DNA-encoded libraries for drug discovery, covering synthesis techniques, pros and cons, and diverse DEL methods.

PROTACs: Catalytic Protein Knockdown Strategy

Explores PROTACs, a catalytic protein knockdown strategy with potential in tumor treatment and drug development.

Introduction: small molecule drugs for cancer

Introduces small molecule drugs for cancer treatment, covering drug discovery, mechanisms of action, and historical development of anti-cancer agents.

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