Concept

Ligand (biochemistry)

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Related lectures (32)

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Receptor-Ligand Interaction: Quantification and Mechanisms

Explores methods to quantify receptor-ligand interactions, ligand-gated ion channels, and the Hill equation.

Protein Folding: Forces and Mechanisms

Explores protein folding forces, including van der Waals interactions, hydrogen bonds, and salt bridges, and their impact on stability.

Pharmacodynamics: Quantitative Description of Ligand-Receptor Binding

Delves into the quantitative aspects of ligand-receptor binding and receptor occupancy.

Nuclear Receptors: Core Signaling

Explores nuclear receptors' core signaling and the impact of endocrine disruptors on the endocrine system, including the inhibitory effects of compounds like eugenol on the estrogen receptor.

Design Optimization in ChemBio

Explores the design optimization of sensors and bioluminescent proteins for drug monitoring and metabolite visualization.

Oxidative Addition and Reductive Elimination

Explores oxidative addition, reductive elimination, insertion reactions, and factors influencing these reactions in organometallic chemistry.

Complexation Chemistry

Covers the thermodynamics of complexation chemistry, explaining metal-ligand complexes and the role of ligands in the environment.

Receptor Tyrosine Kinases: Signalling and Regulation

Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.

Protein-Ligand Interactions

Explores protein-ligand interactions, covering binding affinity, energetics, and various experimental techniques used to study them.

Targeting: Biomaterials and Therapeutics

Delves into passive and active targeting mechanisms in biomaterials for therapeutic delivery to diseased cells, emphasizing the use of liposomes.

Receptor-Ligand Interaction

Explores receptor-ligand interactions, covering binding, dissociation, equilibrium, and quantification methods.

Surface Sensors: Binding Kinetics and Langmuir Isotherm

Explores surface sensors, binding kinetics, Langmuir isotherm, and analyte concentration strategies.

Complexation Chemistry: Principles and Applications

Explores complexation chemistry principles, metal-ligand interactions, toxicity mechanisms, and environmental implications.

Homogeneous Catalysis Basics

Introduces the basics of homogeneous catalysis, focusing on reaction mechanisms and catalyst design.

Cellular Signalling: Introduction & Mechanisms

Covers cellular signalling, including long-distance communication, receptor mechanisms, and the impact of small numbers in biology.

Supramolecular Chemistry: Self-Assembly of Heterobimetallic Systems

Explores the self-assembly of heterobimetallic systems to create robust duplexes in water, emphasizing the importance of synthetic H-bond systems for materials fabrication.

Phosphine Dissociation Mechanisms

Delves into olefin coordination mechanisms, phosphine dissociation, ligand effects, and catalyst reactivity.

Endocytosis of Materials

Delves into the significance of size, shape, and charge in cellular endocytosis processes, emphasizing the design of materials for efficient cellular uptake.

Kinetics: Reaction Rates and Equilibrium

Explores reaction kinetics, rate laws, measurement techniques, and binding kinetics between ligands and proteins.