Lecture

Complexation Chemistry

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Description

This lecture covers the thermodynamics framework of complexation chemistry, including ligands, hard and soft acid and base principle, inner- and outer-sphere complexes, adsorption, and competition among ligands. It explains the formation of metal-ligand complexes, the general equations for complex formation, and the variety of ligands such as soluble inorganic, particle surface, organic, and synthetic ligands. The lecture also discusses the HSAB principle, metal ion hydration spheres, Irwing-Williams series, increasing softness and toxicity of metal ions, and the role of surface ligands in adsorption and immobilization. The key takeaway is that complexation governs the fate of metal ions in the environment and living organisms, influenced by the HSAB principle and explaining toxicity and residence time through complexation reactions.

Official source

Ontological neighbourhood

Chemistry

Inorganic chemistry: Coordination chemistry

Related concepts (32)

Ligand

In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex. The bonding with the metal generally involves formal donation of one or more of the ligand's electron pairs, often through Lewis bases. The nature of metal–ligand bonding can range from covalent to ionic. Furthermore, the metal–ligand bond order can range from one to three. Ligands are viewed as Lewis bases, although rare cases are known to involve Lewis acidic "ligands".

Bridging ligand

In coordination chemistry, a bridging ligand is a ligand that connects two or more atoms, usually metal ions. The ligand may be atomic or polyatomic. Virtually all complex organic compounds can serve as bridging ligands, so the term is usually restricted to small ligands such as pseudohalides or to ligands that are specifically designed to link two metals. In naming a complex wherein a single atom bridges two metals, the bridging ligand is preceded by the Greek letter mu, μ, with a subscript number denoting the number of metals bound to the bridging ligand.

Inorganic chemistry

Inorganic chemistry deals with synthesis and behavior of inorganic and organometallic compounds. This field covers chemical compounds that are not carbon-based, which are the subjects of organic chemistry. The distinction between the two disciplines is far from absolute, as there is much overlap in the subdiscipline of organometallic chemistry. It has applications in every aspect of the chemical industry, including catalysis, materials science, pigments, surfactants, coatings, medications, fuels, and agriculture.

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from Latin ligare, which means 'to bind'. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results in a change of conformational isomerism (conformation) of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion, or protein which binds to the DNA double helix.

Thermodynamics

Thermodynamics is a branch of physics that deals with heat, work, and temperature, and their relation to energy, entropy, and the physical properties of matter and radiation. The behavior of these quantities is governed by the four laws of thermodynamics which convey a quantitative description using measurable macroscopic physical quantities, but may be explained in terms of microscopic constituents by statistical mechanics.

Related lectures (64)

Complexation Chemistry: Principles and Applications

Explores complexation chemistry principles, metal-ligand interactions, toxicity mechanisms, and environmental implications.

Preparation & Stabilities of Complexes

Covers the preparation and stabilities of complexes, including redox reactions, substitution, and catalytic reactions.

Homogeneous Catalysis Basics

Introduces the basics of homogeneous catalysis, focusing on reaction mechanisms and catalyst design.

Coordination Chemistry: Ligands and Geometries

Covers coordination numbers, common ligands, and preferred geometries in coordination chemistry, emphasizing the spatial distribution between ligands and the role of d⁸ electron configurations.

Isomers and Chirality: Understanding Coordination Complexes