Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Lecture

Supramolecular Chemistry: Self-Assembly of Heterobimetallic Systems

In course

CH-424: Supramolecular chemistry

The course provides an introduction to supramolecular chemistry. In addition, current trends are discussed using recent publications in this area. ...

Description

This lecture explores the self-assembly of heterobimetallic systems, focusing on the formation of robust bis(guanidinium)/dicarboxylate heteroduplexes in water. The presentation covers the importance of synthetic H-bond systems for materials fabrication, such as supramolecular polymers and hydrogels. Strategies for developing H-bond-mediated duplex systems with high binding affinities in water are discussed, emphasizing the role of H-bond-assisted ionic pairs. The lecture delves into the analysis methods, including ITC and UV-VIS titration, to assess the binding interactions between the monomers. The goal is to create a high Kass duplex system in water, showcasing the potential for applications in materials science.

This video is available exclusively on Mediaspace for a restricted audience. Please log in to MediaSpace to access it if you have the necessary permissions.

Watch on Mediaspace

Instructor

Kay Severin

Kay Severin was born in Germany in 1967. He obtained his Ph.D. in 1995 with a thesis in the group of Prof. W. Beck, University of Munich. Subsequently, he joined the group of Prof. M. R. Ghadiri as a postdoctoral fellow. In 1997, he started independent research projects ("Habilitation") at the Department of Chemistry, University of Munich. In 2001, he became assistant professor at the Institute of Chemical Sciences and Engineering at the Swiss Federal Institute of Technology, Lausanne (EPFL). Since 2009, he is full professor at the same institute. Awards: Bayerischer Habilitations Förderpreis (1997), ADUC award of the year (2001), Heinz Maier-Leibnitz award of the DFG (2001), award of the Karl-Ziegler foundation (2001), Arnold Sommerfeld award of the Bavarian Academy of Science (2001), Werner Prize of The Swiss Chemical Society (2003), Otto Roelen Medal of the DECHEMA (2005), award for chemistry of the Academy of Sciences, Göttingen (2007), Dalton Transactions European Lectureship (2008).

Official source

Ontological neighbourhood

Chemical engineering

Nanotechnology: Topics in nanotechnology

Related concepts (32)

Self-assembly

Self-assembly is a process in which a disordered system of pre-existing components forms an organized structure or pattern as a consequence of specific, local interactions among the components themselves, without external direction. When the constitutive components are molecules, the process is termed molecular self-assembly. Self-assembly can be classified as either static or dynamic. In static self-assembly, the ordered state forms as a system approaches equilibrium, reducing its free energy.

Supramolecular chemistry

Supramolecular chemistry refers to the branch of chemistry concerning chemical systems composed of a discrete number of molecules. The strength of the forces responsible for spatial organization of the system range from weak intermolecular forces, electrostatic charge, or hydrogen bonding to strong covalent bonding, provided that the electronic coupling strength remains small relative to the energy parameters of the component.

Supramolecular assembly

In chemistry, a supramolecular assembly is a complex of molecules held together by noncovalent bonds. While a supramolecular assembly can be simply composed of two molecules (e.g., a DNA double helix or an inclusion compound), or a defined number of stoichiometrically interacting molecules within a quaternary complex, it is more often used to denote larger complexes composed of indefinite numbers of molecules that form sphere-, rod-, or sheet-like species.

Self-assembly of nanoparticles

Nanoparticles are classified as having at least one of three dimensions be in the range of 1-100 nm. The small size of nanoparticles allows them to have unique characteristics which may not be possible on the macro-scale. Self-assembly is the spontaneous organization of smaller subunits to form larger, well-organized patterns. For nanoparticles, this spontaneous assembly is a consequence of interactions between the particles aimed at achieving a thermodynamic equilibrium and reducing the system’s free energy.

Molecular self-assembly

In chemistry and materials science, molecular self-assembly is the process by which molecules adopt a defined arrangement without guidance or management from an outside source. There are two types of self-assembly: intermolecular and intramolecular. Commonly, the term molecular self-assembly refers to the former, while the latter is more commonly called folding. Molecular self-assembly is a key concept in supramolecular chemistry. This is because assembly of molecules in such systems is directed through non-covalent interactions (e.

Related lectures (43)

Chemical Bonding: Lewis Structures and Molecular Shapes

Explores chemical bonding, Lewis structures, molecular shapes, and molecular polarity.

Polymer Structure in Solution

Explores polymer structure in solution, covering bonding, forces, and properties.

Chemical Bonds: Types and Properties

Explores various chemical bond types and interactions between atoms through electrons, emphasizing the significance of understanding these bond characteristics.

Biomolecular Condensates: Forces and Structures

Explores forces and structures of biomolecular condensates, including direct and indirect forces, compartmentalization, and phase separation of Intrinsically Disordered Proteins.

DPD Simulation: Parameters and Applications