Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

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A novel automated method based on sequential injection analysis (SIA), a non-segmented flow injection technique, was developed to evaluate glutathione S-transferase P1-1 (GST P1-1) activity in the presence of organometallic complexes with putative anticanc ...

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A review. The systematic development of the RAPTA family of organometallic ruthenium(II) anticancer drugs contg. a monodentate 1,3,5-triaza-7-phosphatricyclo-[3.3.1.1]decane ligand and a h6-arene ligand is described. ...

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A review. This review describes a concept aimed at rational and maximal structure proliferation. To this end, simple arom. or heterocyclic starting materials, often bulk chems., are converted into all regioisomerically possible polar organometallic interme ...

This paper is aimed at introducing the organometallic chemist to the fascinating area of organometallic pharmaceuticals. It commences by identifying the properties of organometallic (transition metal) compounds that lend themselves to medical applications. ...

Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

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Impact of substrate clogging on vertical connectivity

Automated approach for the evaluation of glutathione-S-transferase P1-1 inhibition by organometallic anticancer compounds

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Challenges for biophysical modeling of microstructure

Synthetic Studies toward Amanita Phalloides Toxins

Energy efficiency as an example of cross-discipline collaboration in chemical engineering

An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode

Opening the lid on piano-stool complexes: An account of ruthenium(II)-arene complexes with medicinal applications

DprE1-from the Discovery to the Promising Tuberculosis Drug Target

Scientific diasporas, transnationalism and home-country development: evidence from a study of skilled Moldovans abroad

The alignment between institutions and technology in network industries

Visualizing Biochemical Activities in Living Cells through Chemistry

Direct Alkynylation of Indole and Pyrrole Heterocycles

Recent knowledge and innovations related to hexofuranosides: structure, synthesis and applications

Development of organometallic ruthenium(II) anticancer (RAPTA) drugs

Transition metal complexes for inhibiting resistance in the treatment of cancer and metastasis

The 2 * 3 toolbox of organometallic methods for regiochemically exhaustive functionalization

Development of organometallic (organo-transition metal) pharmaceuticals