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A data-driven polynomial approach to reproduce the scar tissue outgrowth around neural implants

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Publications associées (38)

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Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

Stéphanie Lacour

Fibrotic scarring secondary to the foreign body reaction (FBR) generates a physical barrier obstructing the functional interaction of implantable medical devices with the host tissue. The mechanistic basis of the FBR is poorly understood, restricting the c ...

National Academy of Sciences2022

Closed-Loop Neural Interfaces with Embedded Machine Learning

Mahsa Shoaran, Bingzhao Zhu, Uisub Shin

Neural interfaces capable of multi-site electrical recording, on-site signal classification, and closed-loop therapy are critical for the diagnosis and treatment of neurological disorders. However, deploying machine learning algorithms on low-power neural ...

IEEE2020

New particle formation event detection with Mask R-CNN

Lubna Dada

Atmospheric new particle formation (NPF) is an important source of climate-relevant aerosol particles which has been observed at many locations globally. To study this phenomenon, the first step is to identify whether an NPF event occurs or not on a given ...

Copernicus Publications2022

Hand Control With Invasive Feedback Is Not Impaired by Increased Cognitive Load

Silvestro Micera, Ivo Strauss, Giacomo Valle, Francesco Maria Petrini, Edoardo D'Anna

Recent experiments have shown that neural stimulation can successfully restore sensory feedback in upper-limb amputees improving their ability to control the prosthesis. However, the potential advantages of invasive sensory feedback with respect to non-inv ...

2020

Spatiotemporal stimulation strategies in neuroprostheses to improve locomotion after spinal cord injury

Jérôme Gandar

Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of neurological disorders including paralysis. Current rehabilitation strategies to restore locomotion are poorly effective in people with severe SCI. Epidural ...

EPFL2019

Material surface detection on various body parts: a preliminary study for temperature substitution for upper arm amputees

Silvestro Micera, Solaiman Shokur

Experiments have shown that healthy subjects can detect materials solely relying on the material's thermal properties at their fingertip. We are interested in developing a non-invasive temperature display for sensory substitution for patients with arm ampu ...

IEEE2021

Gel-Free Wearable Electroencephalography (EEG) with Soft Graphene Textiles

Ata Jedari Golparvar

Attaching rigid wearables to ones skin may be socially challenging to be accustomed since their wearers may feel vulnerable with compromising their privacy, especially if the device is for tracking neurological or medical conditions. The development of fle ...

IEEE2021

Wireless Power Transfer and Data Communication for Implantable Autonomous Monitoring and Detection of Epilepsy In Vivo

Kerim Türe

The impact of technological advancement became significant and still has an essential role to play in the diagnosis and treatment of diseases. Nowadays, personalized medicine and therapy are on the rise as a consequence of the developed and cheaper medical ...

EPFL2019

Nonlinear Frequency Conversion in the Hybrid Silicon Nitride - Lithium Niobate Integrated Platform

Tobias Kippenberg, Junqiu Liu, Rui Ning Wang, Mikhail Churaev, Viacheslav Snigirev, Terence Albert Emile Blésin

We demonstrate optical frequency comb generation in hybrid high-Q optical microresonators fabricated using direct wafer bonding of photonic Damascene silicon nitride wafer with thin-film lithium niobate-on-insulator (LNOI). The devices enable direct phase ...

IEEE2021

Microchannel-based technologies for nerve interfacing

Sandra Gribi

Biomedical technologies in neuroprosthetics are made to restore or replace functions from the nervous system, as well as alleviate pathological conditions. Peripheral nerve interfaces use neuromodulatory techniques to inhibit pain or depression, prevent ep ...

EPFL2019

Soft multimodal neural interfaces for unravelling sensory neurological circuits

Frédéric Pierre Gérald Michoud

Diseases or injuries affecting the nervous system can dramatically disrupt the quality of life. Despite extensive efforts towards treating dysfunctional nervous systems, the pharmacological and electrical approaches generally involved lack the temporal and ...

EPFL2019

An Off-the-Shelf Tissue Engineered Cartilage Composed of Optimally Sized Pellets of Cartilage Progenitor/Stem Cells

Dominique Pioletti

Articular cartilage focal lesion remains an intractable challenge in sports medicine, and autologous chondrocytes' implantation (ACI) is one of the most commonly utilized treatment modality for this ailment. However, the current ACI technique requires two ...

AMER CHEMICAL SOC2021

Auditory Brainstem Implants: Recent Progress and Future Perspectives

Stéphanie Lacour, Nicolas Vachicouras

The auditory brainstem implant (ABI) was first developed nearly 40 years ago and provides auditory rehabilitation to patients who are deaf and ineligible for cochlear implant surgery due to abnormalities of the cochlea and cochlear nerve. The aims of the f ...

2019

A Software Tool for the Real-Time in Vivo Evaluation of Neural Electrodes' Selectivity

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss

High neural selectivity is an important indicator of how well a neural electrode will perform in a clinical setup. Among other factors, neural selectivity of an electrode strongly depends on its implant location. Today, the neural selectivity is evaluated ...

IEEE2021

Soft materials and technologies for neural interfaces

Michael Shur

Implantable neural interfaces are an emerging concept which is revolutionizing various domains of medicine and rehabilitation. However, the long-term efficiency and reliability of these devices is often limited, mainly attributed to the fundamental differe ...

EPFL2021

A system for planning and/or providing neuromodulation

Grégoire Courtine, Marco Capogrosso, Fabien Bertrand Paul Wagner, Vincent Delattre, Karen Minassian

The present invention relates to a system for planning and/or providing neuromodulation (10), especially neurostimulation, comprising: - first data input module (26) for stimulation related basic data, - a stimulation related basic data storage module (28) ...

2019

A system for planning and/or providing neuromodulation

Grégoire Courtine, Marco Capogrosso, Fabien Bertrand Paul Wagner, Vincent Delattre, Karen Minassian

The present invention relates to a system for planning and/or providing neuromodulation (10), especially neurostimulation, comprising - a stimulation related basic data storage module (28) for storing the stimulation related basic data, - a stimulation rel ...

2019

High-Resolution Multi-Spectral Imaging With Diffractive Lenses and Learned Reconstruction

Oguzhan Fatih Kar

Spectral imaging is a fundamental diagnostic technique with widespread application. Conventional spectral imaging approaches have intrinsic limitations on spatial and spectral resolutions due to the physical components they rely on. To overcome these physi ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021