A data-driven polynomial approach to reproduce the scar tissue outgrowth around neural implants

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Fibrotic scarring secondary to the foreign body reaction (FBR) generates a physical barrier obstructing the functional interaction of implantable medical devices with the host tissue. The mechanistic basis of the FBR is poorly understood, restricting the c ...

Neural interfaces capable of multi-site electrical recording, on-site signal classification, and closed-loop therapy are critical for the diagnosis and treatment of neurological disorders. However, deploying machine learning algorithms on low-power neural ...

Atmospheric new particle formation (NPF) is an important source of climate-relevant aerosol particles which has been observed at many locations globally. To study this phenomenon, the first step is to identify whether an NPF event occurs or not on a given ...

Recent experiments have shown that neural stimulation can successfully restore sensory feedback in upper-limb amputees improving their ability to control the prosthesis. However, the potential advantages of invasive sensory feedback with respect to non-inv ...

Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of neurological disorders including paralysis. Current rehabilitation strategies to restore locomotion are poorly effective in people with severe SCI. Epidural ...

Experiments have shown that healthy subjects can detect materials solely relying on the material's thermal properties at their fingertip. We are interested in developing a non-invasive temperature display for sensory substitution for patients with arm ampu ...

Attaching rigid wearables to ones skin may be socially challenging to be accustomed since their wearers may feel vulnerable with compromising their privacy, especially if the device is for tracking neurological or medical conditions. The development of fle ...

The impact of technological advancement became significant and still has an essential role to play in the diagnosis and treatment of diseases. Nowadays, personalized medicine and therapy are on the rise as a consequence of the developed and cheaper medical ...

We demonstrate optical frequency comb generation in hybrid high-Q optical microresonators fabricated using direct wafer bonding of photonic Damascene silicon nitride wafer with thin-film lithium niobate-on-insulator (LNOI). The devices enable direct phase ...

Biomedical technologies in neuroprosthetics are made to restore or replace functions from the nervous system, as well as alleviate pathological conditions. Peripheral nerve interfaces use neuromodulatory techniques to inhibit pain or depression, prevent ep ...

Diseases or injuries affecting the nervous system can dramatically disrupt the quality of life. Despite extensive efforts towards treating dysfunctional nervous systems, the pharmacological and electrical approaches generally involved lack the temporal and ...

Articular cartilage focal lesion remains an intractable challenge in sports medicine, and autologous chondrocytes' implantation (ACI) is one of the most commonly utilized treatment modality for this ailment. However, the current ACI technique requires two ...

The auditory brainstem implant (ABI) was first developed nearly 40 years ago and provides auditory rehabilitation to patients who are deaf and ineligible for cochlear implant surgery due to abnormalities of the cochlea and cochlear nerve. The aims of the f ...

High neural selectivity is an important indicator of how well a neural electrode will perform in a clinical setup. Among other factors, neural selectivity of an electrode strongly depends on its implant location. Today, the neural selectivity is evaluated ...

Implantable neural interfaces are an emerging concept which is revolutionizing various domains of medicine and rehabilitation. However, the long-term efficiency and reliability of these devices is often limited, mainly attributed to the fundamental differe ...

The present invention relates to a system for planning and/or providing neuromodulation (10), especially neurostimulation, comprising: - first data input module (26) for stimulation related basic data, - a stimulation related basic data storage module (28) ...

The present invention relates to a system for planning and/or providing neuromodulation (10), especially neurostimulation, comprising - a stimulation related basic data storage module (28) for storing the stimulation related basic data, - a stimulation rel ...

Spectral imaging is a fundamental diagnostic technique with widespread application. Conventional spectral imaging approaches have intrinsic limitations on spatial and spectral resolutions due to the physical components they rely on. To overcome these physi ...

A data-driven polynomial approach to reproduce the scar tissue outgrowth around neural implants

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