Publications associées à Ultrasensitive Label-Free Detection of Protein–Membrane Interaction Exemplified by Toxin-Liposome Insertion

Publications associées (11)

Tracking spatiotemporal localisation and interactions of the innate immune sensor STING

Innate immunity, the very first line of defence of our cells, relies on the detection of universal pathogen- or danger-associated signals to launch an inflammatory response. A crucial part of our innate immune system is based on the recognition of out-of-c ...

EPFL2023

A general method for the development of multicolor biosensors with large dynamic ranges

Kai Johnsson

Fluorescent biosensors enable the study of cell physiology with spatiotemporal resolution; yet, most biosensors suffer from relatively low dynamic ranges. Here, we introduce a family of designed Forster resonance energy transfer (FRET) pairs with near-quan ...

NATURE PORTFOLIO2023

Hypervalent Iodine-Mediated Late-Stage Peptide and Protein Functionalization

Jérôme Waser, Elija Grinhagena, Emmanuelle Madeline Dominique Allouche

Hypervalent iodine compounds are powerful reagents for the development of novel transformations. As they exhibit low toxicity, high functional group tolerance, and stability in biocompatible media, they have been used for the functionalization of biomolecu ...

Wiley-VCH Verlag GmbH2022

Integration of polymeric membrane/dielectric sphere assemblies in microfluidic chips for enhanced-contrast imaging with low-magnification systems

Martinus Adela Maria Gijs, Daniel Migliozzi, Vittorio Viri

Current microscopy systems for the imaging of microorganisms are expensive because of their optimized design toward resolution maximization and aberration correction. In situations where such an optimization is not needed, for instance to merely detect the ...

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS2021

Membrane expression of the estrogen receptor ER alpha is required for intercellular communications in the mammary epithelium

Cathrin Brisken, Stéphanie Cagnet

17 beta-Estradiol induces the postnatal development of mammary gland and influences breast carcinogenesis by binding to the estrogen receptor ER alpha. ER alpha acts as a transcription factor but also elicits rapid signaling through a fraction of ER alpha ...

2020

Fabrication and Packaging of a Fully Implantable Biosensor Array

Giovanni De Micheli, Sandro Carrara, Catherine Dehollain, Camilla Baj-Rossi, Seyedeh Sara Ghoreishizadeh, Enver Gürhan Kilinç

In this work, we showed the realization of a fully- implantable device that integrates a microfabricated sensing platform, a coil for power and data transmission and integrated circuits. We described a device intended to test the biocompati- bility of the ...

2013

Direct Visualization of Single Ions in the Stern Layer of Calcite

Jean-François Molinari, Francesco Stellacci, Kislon Voitchovsky, Peter Spijker, Maria Ricci

Calcite is among the most abundant minerals on earth and plays a central role in many environmental and geochemical processes. Here we used amplitude modulation atomic force microscopy (AFM) operated in a particular regime to visualize single ions close to ...

American Chemical Society2013

Secondary Structure Assignment of Amyloid-β Peptide Using Chemical Shifts

Ursula Röthlisberger

The distinct conformational dependence of chemical shifts caused by R-helices and β-sheets renders NMR chemical shift analysis a powerful tool for the structural determination of proteins. However, the time scale of NMR experiments can make a secondary str ...

2011

Surface Nanopatterning by Polymer Self-Assembly: from Applied Research to Industrial Applications

Jeffrey Alan Hubbell

Complementary methods have been developed for surface nanostructuring using molecular self-assembly, reactive ion etching and replication techniques. First, controlled surface nanostructures with tunable lateral dimensions from tens of nanometer to tens of ...

2009

Polyelectrolyte complex formation at defined interfaces and structure formation in solution studied by analytical ultracentrifugation

Laurent Bourdillon

The interactions and structural formation of polyelectrolytes in solution and environmental stimuli-responsive water-soluble polymers are subjects of intense academic research, development, and application. An increasing number of novel materials are being ...

EPFL2006

Stencil lithography : an ancient technique for advanced micro- and nano-patterning

Marc Antonius Friedrich van den Boogaart

This work describes the advancements made in micro and nano patterning via stencil lithography. Stencil lithography is a resist-less and direct pattern technique where a controlled amount of material is deposited through apertures on to a substrate in a va ...

EPFL2006