Safe Implementation of Embedded Software for a Portable Device Supporting Drug Administration

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Dehydration is a frequent condition in the elderly and can lead to serious health complications if not compensated timely. Early diagnosis can be problematic, as medical examinations in the hospital would be needed. Fully wearable low-cost multisensing dev ...

Acute leukemia has a high mortality rate of approximately 50%, and current methods are not effective in predicting disease progression and relapse. To improve our understanding of hematopoiesis and develop new markers for predicting disease relapse in dead ...

Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used to treat retinoblastoma, all have been repurposed from drugs developed for other conditions. In order to find drugs or drug combinations better suited to the improv ...

Vimentin is a main type 3 intermediate filament protein. It seems that abnormal expression of vimentin is contributed to the appearance of the aggressive feature of cancer cells. So that it has been reported that malignancy and epithelial-mesenchymal trans ...

Systems and methods for monitoring penile tumescence are provided that overcome the drawbacks of previously known systems by providing a wearable formed of a flexible and elastic tube having a plurality of sensors disposed on or embedded within it, the wea ...

This article presents a design-for-test methodology for embedded memories. The methodology relies on a fully random fault model of post-fabrication errors, which results in a low-overhead test strategy. The methodology's effectiveness is demonstrated on an ...

Resistance remains the major clinical challenge for the therapy of Philadelphia chromosome-positive (Ph+) leukemia. With the exception of ponatinib, all approved tyrosine kinase inhibitors (TKIs) are unable to inhibit the common "gatekeeper" mutation T315I ...

Recent advances in Model Predictive Control (MPC) algorithms and methodologies, combined with the surge of computational power of available embedded platforms, allows the use of real-time optimization-based control of fast mechatronic systems. This paper p ...

Chronic lymphocytic leukemia (CLL) is a B cell malignancy and represents the most common leukemia in adults within the Western world. This disease mainly affects the elderly, with a median age of diagnosis over 70. The disease course is highly variable amo ...

This book defines and explores the problem of placing the instances of dynamic data types on the components of the heterogeneous memory organization of an embedded system, with the final goal of reducing energy consumption and improving performance. It is ...

We use quantitative phase digital holographic microscopy (QP-DHM) to image and quantify the beating movement of cardiomyocytes, derived from induced pluripotent stem cells (iPSCs), in control and drug-treated conditions. The development of an analysis algo ...

A series of three formulations were prepared in view of experimental and theoretical investigation of their drug release potential. The morphology of the film formulations, in terms of distribution of drug into the polymeric matrix and the nature of the dr ...

Embedded systems are deployed in security critical environments and have become a prominent target for remote attacks. Microcontroller-based systems (MCUS) are particularly vulnerable due to a combination of limited resources and low level programming whic ...

The BCR-ABL1 fusion protein is the cause of chronic myeloid leukemia (CML) and of a significant fraction of adult-onset B cell acute lymphoblastic leukemia (B-ALL) cases. Using mouse models and patient-derived samples, we identified an essential role for γ ...

Smart health monitoring devices, known as Wireless Body Sensor Nodes (WBSN) are transforming today's health-care landscape, shifting it from traditional hospital-based methods toward more personalized approaches. Their demand is ever-increasing in the mode ...

The capability to process high-resolution videos in real-time is becoming more important in a wide variety of applications such as autonomous vehicles, virtual reality or intelligent surveillance systems. The high-accuracy and complex video processing algo ...

to follow up patients who inject themselves insulin with injection pen is a quite complex task. Due to the repetition of injections, and the numerous influent parameter the patient can easily made an injection mistake and it is difficult for health-takers ...

Improved sensitivity and continuous monitoring of therapeutic compounds are two of the most highlighted concerns for the treatment of malignant diseases, such as cancer. We demonstrated ultrasensitive screening of etoposide, a therapeutic compound widely-u ...

The efficacy of the standardized four-drug regimen (comprising isoniazid, rifampin, pyrazinamide, and ethambutol) for the treatment of tuberculosis (TB) is menaced by the emergence of multidrug-resistant (MDR) and extensively drugresistant (XDR) strains of ...

When studying the drug effectiveness towards a target model, one should distinguish the effects of the drug itself and of all the other factors that could influence the screening outcome. This comprehensive knowledge is crucial, especially when model organ ...

Safe Implementation of Embedded Software for a Portable Device Supporting Drug Administration

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Design and in vitro Characterization of a Wearable Multisensing System for Hydration Monitoring

Novel quantitative bioengineered tools to track human bone marrow niche cellular constituents in health and disease

The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma

Caspase-9-mediated cleavage of vimentin attenuates the aggressiveness of leukemic NB4 cells

Tumescense monitoring system for diagnosing erectile dysfunction and methods of use

Design for Test With Unreliable Memories by Restoring the Beauty of Randomness

Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and BCR-ABL1(T315I-E255K)

Optimal Thrust Vector Control of an Electric Small-Scale Rocket Prototype

Notch Signaling - a Booster of Chronic Lymphocytic Leukemia During Initiation and Disease Progression

Heterogeneous Memory Organizations in Embedded Systems. Placement of Dynamic Data Objects

Marker-Free Automatic Quantification of Drug-Treated Cardiomyocytes with Digital Holographic Imaging

Experimental And Theoretical Insight Into Formulations Based On Poly(Vinyl Alcohol Boric Acid) And Diclofenac Sodium Salt

mu RAI: Securing Embedded Systems with Return Address Integrity

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

Hardware/Software Co-Design and Reliability Analysis of Ultra-Low Power Biomedical Devices

A Real-Time Multi-Camera Depth Estimation ASIC with Custom On-Chip Embedded DRAM

Modeling of a capacitive sensor dedicated to drug injection

Graphene nanowalls for high-performance chemotherapeutic drug sensing and anti-fouling properties

Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169)

A design of experiment approach for efficient multi-parametric drug testing using a Caenorhabditis elegans model