Aging and matrix viscoelasticity affect multiscale tendon properties and tendon derived cell behavior

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To explore the governing mechanism underlying the tensile fatigue behavior of Ultra-high Performance Fiber Reinforced Cementitious Composites (UHPFRC), this study tested eight specimens using four advanced non-destructive measurement techniques. First, mag ...

In geological reservoirs, pore fluid chemistry can affect rock strength by inducing mineral dissolution, precipitation, and alteration, among other processes. Increasing pressure and temperature can shift deformation from localized to ductile, decreasing p ...

Skin-like bioelectronics offer a transformative technological frontier, catering to continuous and real-time yet highly imperceptible and socially discreet digital healthcare. The key technological breakthrough enabling these innovations stems from advance ...

The precise control of transcription factor (TF) concentrations is crucial for While TF concentration gradients are well-characterized in model organisms like Drosophila and Caenorhabditis elegans, their quantitative relationship with genomic occupancy in ...

Articular cartilage focal lesion remains an intractable challenge in sports medicine, and autologous chondrocytes' implantation (ACI) is one of the most commonly utilized treatment modality for this ailment. However, the current ACI technique requires two ...

Tissues morphogenesis and homeostasis involve the spatiotemporal regulation of mechanics at multiple scales. Characterization of mechanical properties of biological systems as well as investigating the effects of mechanical forces on biological function ar ...

The misfolding and self-assembly of proteins into fibrils is a hallmark of several neurodegenerative and systemic diseases. These disease-associated proteins have the propensity to form fibrils with a cross-Î² sheet structure, called amyloids. Amyloids can ...

Estrogens and progesterone control breast development and carcinogenesis via their cognate receptors expressed in a subset of luminal cells in the mammary epithelium. How they control the extracellular matrix, important to breast physiology and tumorigenes ...

Titanium-based Metal Matrix Composites (MMCs) manufactured by additive manufacturing offer tremendous lightweighting opportunities. However, processing the high reinforcement contents needed to substantially improve elastic modulus while conserving signifi ...

In this work, the macrotexture of dense Zn produced by laser powder bed fusion (LPBF) was studied and the mechanical properties for different tensile bar orientations were measured. The compressive strength of LPBF Zn scaffolds with five different unit cel ...

Naïve epiblast cells in the embryo and pluripotent stem cells in vitro undergo developmental progression to a formative state competent for lineage specification. During this transition, transcription factors and chromatin are rewired to encode new functio ...

Ovarian hormones control mammary gland development and impinge on breast carcinogenesis acting via their cognate receptors in the luminal epithelium. The extracellular matrix has a key role in physiology and disease but how the two are linked is poorly und ...

Wind turbine rotor blades are usually fabricated using composite materials and epoxy adhesive to bond the elements together. Due to their large size, the thickness of the adhesive layer varies from 1 to up to 30 mm depending on the position. The failure of ...

Transmission electron microscopy (TEM) offers an ample range of complementary techniques which are able to provide essential information about the physical, chemical and structural properties of materials at the atomic scale, and hence makes a vast impact ...

Glandular epithelia, including mammary gland (MG) and prostate, are composed of luminal and basal cells. During embryonic development, glandular epithelia arise from multipotent stem cells (SCs) that are replaced after birth by unipotent basal and unipoten ...

Chronic and acute tendon injuries are frequent afflictions, for which treatment is often long and unsatisfactory. When facing extended injuries, matrices and scaffolds with sufficient biomechanical properties are required for surgical repair and could addi ...

The construction industry has recently increased the adoption of additive manufacturing (AM, also known as 3D-printing) technologies. This review paper presents the state of the art of ground-based AM systems in construction, focusing comprehensively on de ...

Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid biosynthesis and adipogenesis by controlling the expression of several enzymes required for cholesterol, fatty acid, triacylglycerol and phospholi ...

Collagen-rich tissues in the cornea exhibit unique and highly organized extracellular matrix ultrastructures, which contribute to its high load-bearing capacity and light transmittance. Corneal collagen fibrils are controlled during development by small le ...

Adult hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow (BM) hematopoietic niche, which regulates HSPC quiescence, self-renewal, and commitment in a demand-adapted manner. Although the complex BM niche is responsible for adult hemat ...

Aging and matrix viscoelasticity affect multiscale tendon properties and tendon derived cell behavior

Chattez avec Graph Search

Deciphering tensile fatigue behavior of UHPFRC using magnetoscopy, DIC and acoustic emission

Fluid Chemistry Effect on Localized and Ductile Deformation of a Porous Sandstone

Highly Self-Adhesive and Biodegradable Silk Bioelectronics for All-In-One Imperceptible Long-Term Electrophysiological Biosignals Monitoring

The Regulation of Transcription Factors Binding Site Occupancies by Their Concentrations

An Off-the-Shelf Tissue Engineered Cartilage Composed of Optimally Sized Pellets of Cartilage Progenitor/Stem Cells

Wireless soft microscale actuators and robotic devices to study mechanobiology

Gold nanoparticles as a new tool in amyloid studies

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Tensile Properties of Ex-Situ Ti-TiC Metal Matrix Composites Manufactured by Laser Powder Bed Fusion

Mechanical properties and cytocompatibility of dense and porous Zn produced by laser powder bed fusion for biodegradable implant applications

ERK signalling eliminates Nanog and maintains Oct4 to drive the formative pluripotency transition

Adamts18 Function in Mammary Gland Development

Improved Material Formulations for Thick Adhesive Joints in Wind Turbine Blades

Understanding semiconductor nanostructures via advanced electron microscopy and spectroscopy

Collagen signaling and matrix stiffness regulate multipotency in glandular epithelial stem cells in mice

Efficient decellularization of equine tendon with preserved biomechanical properties and cytocompatibility for human tendon surgery indications

The rise of aerial additive manufacturing in construction: a review of material advancements

Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism

Cyclodextrin Modulated Type I Collagen Self-Assembly to Engineer Biomimetic Cornea Implants

Inducible CXCL12/CXCR4–dependent extramedullary hematopoietic niches in the adrenal gland