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Stanisa Raspopovic

Cette personne a quitté l’EPFL

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Publications associées (33)

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Enhancing functional abilities and cognitive integration of the lower limb prosthesis

Silvestro Micera, Stanisa Raspopovic, Giacomo Valle, Francesco Maria Petrini

Lower limb amputation (LLA) destroys the sensory communication between the brain and the external world during standing and walking. Current prostheses do not restore sensory feedback to amputees, who, relying on very limited haptic information from the st ...

2019

Framework for the Development of Neuroprostheses: From Basic Understanding by Sciatic and Median Nerves Models to Bionic Legs and Hands

Stanisa Raspopovic, Giacomo Valle, Francesco Maria Petrini

Neuroprostheses based on electrical stimulation are becoming a therapeutic reality, dramatically improving the life of disabled people. They are based on neural interfaces that are designed to create an intimate contact with neural cells. These devices spe ...

Ieee-Inst Electrical Electronics Engineers Inc2017

Comparison of linear frequency and amplitude modulation for intraneural sensory feedback in bidirectional hand prostheses

Silvestro Micera, Francesco Maria Petrini, Ivo Strauss, Stanisa Raspopovic, Giacomo Valle, Pablo Garcia del Valle, Edoardo D'Anna, Valeria Granata

Recent studies have shown that direct nerve stimulation can be used to provide sensory feedback to hand amputees. The intensity of the elicited sensations can be modulated using the amplitude or frequency of the injected stimuli. However, a comprehensive c ...

Nature Research2018

Sensory feedback restoration in leg amputees improves walking speed, metabolic cost and phantom pain

Silvestro Micera, Stanisa Raspopovic, Giacomo Valle, Francesco Maria Petrini

Conventional leg prostheses do not convey sensory information about motion or interaction with the ground to aboveknee amputees, thereby reducing confidence and walking speed in the users that is associated with high mental and physical fatigue(1-4). The l ...

2019

Long-term usability and bio-integration of polyimide-based intraneural stimulating electrodes

Silvestro Micera, Grégoire Courtine, Marco Capogrosso, Stanisa Raspopovic, Alessandra Piersigilli, Quentin Barraud, Nawal Noëlle Kinany, Jacopo Rigosa, Sophie Marie Marthe Wurth, Jérôme Gandar, Natalia Pavlova

Stimulation of peripheral nerves has transiently restored lost sensation and has the potential to alleviate motor deficits. However, incomplete characterization of the long-term usability and bio-integration of intra-neural implants has restricted their us ...

Elsevier Sci Ltd2017

Six-Month Assessment of a Hand Prosthesis with Intraneural Tactile Feedback

Silvestro Micera, Ivo Strauss, Stanisa Raspopovic, Giacomo Valle, Francesco Maria Petrini, Edoardo D'Anna

Objective Hand amputation is a highly disabling event, which significantly affects quality of life. An effective hand replacement can be achieved if the user, in addition to motor functions, is provided with the sensations that are naturally perceived whil ...

2019

Neural signal recording and processing in somatic neuroprosthetic applications. A review

Silvestro Micera, Stanisa Raspopovic

Neurointerfaces have acquired major relevance as both rehabilitative and therapeutic tools for patients with spinal cord injury, limb amputations and other neural disorders. Bidirectional neural interfaces are a key component for the functional control of ...

ELSEVIER2020

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Silvestro Micera, Marco Capogrosso, Stanisa Raspopovic, Francesco Maria Petrini, Jacopo Rigosa

Background:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the process-ing of descending efferent neural signals recorded using peripheral neural interfaces ...

2019

Characterization of multi-channel intraneural stimulation in transradial amputees

Silvestro Micera, Stanisa Raspopovic, Fiorenzo Artoni, Ivo Strauss, Giacomo Valle, Francesco Maria Petrini, Pablo Garcia del Valle, Edoardo D'Anna

Although peripheral nerve stimulation using intraneural electrodes has been shown to be an effective and reliable solution to restore sensory feedback after hand loss, there have been no reports on the characterization of multi-channel stimulation. A deepe ...

Springer Nature2019

Stability of flexible thin-film metallization stimulation electrodes: analysis of explants after first-in-human study and improvement ofin vivoperformance

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

Objective.Micro-fabricated neural interfaces based on polyimide (PI) are achieving increasing importance in translational research. The ability to produce well-defined micro-structures with properties that include chemical inertness, mechanical flexibility ...

2020

Sensitivity to temporal parameters of intraneural tactile sensory feedback

Silvestro Micera, Stanisa Raspopovic, Ivo Strauss, Giacomo Valle, Francesco Maria Petrini, Edoardo D'Anna

Background Recent studies have shown that neural stimulation can be used to provide artificial sensory feedback to amputees eliciting sensations referred on the amputated hand. The temporal properties of the neural stimulation modulate aspects of evoked se ...

BioMed Central2020

Decoding of grasping tasks from intraneural recordings in trans-radial amputee

Silvestro Micera, Stanisa Raspopovic, Ivo Strauss, Giacomo Valle, Francesco Maria Petrini

Objective. A major challenge in neuroprosthetics is the restoration of sensory-motor hand functions in upper-limb amputees. Neuroprostheses based on the direct re-connection of the peripheral nerves may be an interesting approach for re-establishing the na ...

2020

A Software Tool for the Real-Time in Vivo Evaluation of Neural Electrodes' Selectivity

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss

High neural selectivity is an important indicator of how well a neural electrode will perform in a clinical setup. Among other factors, neural selectivity of an electrode strongly depends on its implant location. Today, the neural selectivity is evaluated ...

IEEE2021

Sensory-Motor Neurostimulation to Enhance Exosuit Performance

Silvestro Micera, Stanisa Raspopovic, Giacomo Valle, Andrea Crema

Exosuits typically provide limited mechanical support and rely on a user's residual functional ability. However, people with neurological impairments often suffer from both motor and sensory deficits that limit the assistance an exosuit can provide. To ove ...

IEEE2023

Closed-loop neuromodulation of spinal sensorimotor circuits controls refined locomotion after complete spinal cord injury

Silvestro Micera, Grégoire Courtine, Stanisa Raspopovic, Eduardo Martin Moraud, Nikolaus Wenger, Marco Bonizzato, Pavel Musienko, John Francis Di Giovanna

Neuromodulation of spinal sensorimotor circuits improves motor control in animal models and humans with spinal cord injury. With common neuromodulation devices, electrical stimulation parameters are tuned manually and remain constant during movement. We de ...

American Association for the Advancement of Science2014

Corrigendum: A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use (vol 3, 619280, 2021)

Silvestro Micera, Ivo Strauss, Stanisa Raspopovic, Giacomo Valle, Francesco Maria Petrini, Edoardo D'Anna

2022

Intrafascicular electrode implant

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

An implantable device for intrafascicular stimulation and/or sensing of a peripheral nerve, including a blocking element adapted for wrapping a nerve, comprising an access point and an exit point, and an electrode adapted to traverse the blocking element v ...

2018

Bringing sensation to prosthetic hands-chronic assessment of implanted thin-film electrodes in humans

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Direct stimulation of peripheral nerves with implantable electrodes successfully provided sensory feedback to amputees while using hand prostheses. Longevity of the electrodes is key to success, which we have improved for the polyimide-based transverse int ...

2023

Real-Time Neural Signals Decoding onto Off-the-Shelf DSP Processors for Neuroprosthetic Applications

Silvestro Micera, Stanisa Raspopovic

The control of upper limb neuroprostheses through the peripheral nervous system (PNS) can allow restoring motor functions in amputees. At present, the important aspect of the realtime implementation of neural decoding algorithms on embedded systems has bee ...

Ieee-Inst Electrical Electronics Engineers Inc2016

A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Edoardo D'Anna

2021